7PJH
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![BU of 7pjh by Molmil](/molmil-images/mine/7pjh) | Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8 | 分子名称: | Pre-mRNA-processing-splicing factor 8, Protein AAR2 homolog | 著者 | Preussner, M, Santos, K, Heroven, A.C, Alles, J, Heyd, F, Wahl, M.C, Weber, G. | 登録日 | 2021-08-24 | 公開日 | 2022-11-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8. Acta Crystallogr D Struct Biol, 78, 2022
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8C6J
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![BU of 8c6j by Molmil](/molmil-images/mine/8c6j) | Human spliceosomal PM5 C* complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | 著者 | Dybkov, O, Kastner, B, Luehrmann, R. | 登録日 | 2023-01-12 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023
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5DCA
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![BU of 5dca by Molmil](/molmil-images/mine/5dca) | Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain | 分子名称: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | 著者 | Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. | 登録日 | 2015-08-23 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes Dev., 29, 2015
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6TW2
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![BU of 6tw2 by Molmil](/molmil-images/mine/6tw2) | Re-refined crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor | 分子名称: | Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate | 著者 | Loll, B, Haltenhof, T, Heyd, F, Wahl, M.C. | 登録日 | 2020-01-12 | 公開日 | 2020-02-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Mol.Cell, 78, 2020
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6TEO
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![BU of 6teo by Molmil](/molmil-images/mine/6teo) | Crystal structure of a yeast Snu114-Prp8 complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | 著者 | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | 登録日 | 2019-11-12 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
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