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6E0G
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Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
6E0F
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Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
4CBQ
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Crystal structure of the thioredoxin reductase from Entamoeba histolytica with auranofin Au(I) bound to Cys286
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, ...
著者Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M.
登録日2013-10-16
公開日2014-11-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.
J.Struct.Biol., 194, 2016
4CW9
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Entamoeba histolytica thiredoxin C34S mutant
分子名称: THIOREDOXIN
著者Parsonage, D, Kells, P.M, Vieira, D.F, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M.
登録日2014-04-01
公開日2015-05-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.
J.Struct.Biol., 194, 2016
1N8J
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BU of 1n8j by Molmil
Crystal Structure of AhpC with Active Site Cysteine mutated to Serine (C46S)
分子名称: Alkyl hydroperoxide reductase C22 protein
著者Wood, Z.A, Poole, L.B, Karplus, P.A.
登録日2002-11-20
公開日2003-04-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling
Science, 300, 2003
4CCQ
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Crystal structure of the thioredoxin reductase from Entamoeba histolytica with NADP
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M.
登録日2013-10-24
公開日2014-11-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.
J.Struct.Biol., 194, 2016
4CCR
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Crystal structure of the thioredoxin reductase apoenzyme from Entamoeba histolytica in the absence of the NADP cofactor
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, THIOREDOXIN REDUCTASE
著者Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M.
登録日2013-10-25
公開日2014-11-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.
J.Struct.Biol., 194, 2016
4MAB
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Resolving Cys to Ala variant of Salmonella Alkyl Hydroperoxide Reductase C in its substrate-ready conformation
分子名称: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, GLYCEROL, ...
著者Perkins, A, Nelson, K.J, Williams, J.R, Poole, L.B, Karplus, P.A.
登録日2013-08-15
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
Biochemistry, 52, 2013
1HYU
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CRYSTAL STRUCTURE OF INTACT AHPF
分子名称: ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Wood, Z.A, Poole, L.B, Karplus, P.A.
登録日2001-01-22
公開日2001-02-14
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of intact AhpF reveals a mirrored thioredoxin-like active site and implies large domain rotations during catalysis.
Biochemistry, 40, 2001
4GQF
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Aeropyrum pernix Peroxiredoxin Q Enzyme in the Locally Unfolded Conformation
分子名称: GLYCEROL, SULFATE ION, Thiol peroxidase
著者Perkins, A, Karplus, P.A, Gretes, M.C, Nelson, K.J, Poole, L.B.
登録日2012-08-22
公開日2012-10-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes.
Biochemistry, 51, 2012
4GQC
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Crystal Structure of Aeropyrum pernix Peroxiredoxin Q Enzyme in Fully-Folded and Locally-Unfolded Conformations
分子名称: DITHIANE DIOL, GLYCEROL, SULFATE ION, ...
著者Perkins, A, Karplus, P.A, Gretes, M.C, Nelson, K.J, Poole, L.B.
登録日2012-08-22
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes.
Biochemistry, 51, 2012
1XW4
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Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Sulfiredoxin
著者Murray, M.S, Jonsson, T.J, Johnson, L.C, Poole, L.B, Lowther, W.T.
登録日2004-10-29
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Biochemistry, 44, 2005
1XW3
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Crystal Structure of Human Sulfiredoxin (Srx)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, SULFIREDOXIN
著者Murray, M.S, Jonsson, T.J, Johnson, L.C, Poole, L.B, Lowther, W.T.
登録日2004-10-29
公開日2005-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Biochemistry, 44, 2005
1YF0
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BU of 1yf0 by Molmil
Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-29
公開日2005-08-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
1ZYN
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BU of 1zyn by Molmil
Oxidized structure of the N-terminal domain of Salmonella typhimurium AhpF
分子名称: Alkyl hydroperoxide reductase subunit F
著者Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A.
登録日2005-06-10
公開日2005-06-21
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF
Protein Sci., 14, 2005
1ZYP
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Synchrotron reduced form of the N-terminal domain of Salmonella typhimurium AhpF
分子名称: Alkyl hydroperoxide reductase subunit F
著者Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A.
登録日2005-06-10
公開日2005-06-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF
Protein Sci., 14, 2005
1YF1
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Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SODIUM ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-29
公開日2005-08-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
1YEX
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Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-28
公開日2005-08-16
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
1YEP
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BU of 1yep by Molmil
Structural and biochemical analysis of the link between enzymatic activity and olgomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-28
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
5IMV
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BU of 5imv by Molmil
Xanthomonas campestris Peroxiredoxin Q - Structure F6
分子名称: Bacterioferritin comigratory protein, FORMIC ACID, SODIUM ION
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-07
公開日2016-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016
5IOX
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BU of 5iox by Molmil
Xanthomonas campestris Peroxiredoxin Q - Structure LUss
分子名称: Bacterioferritin comigratory protein
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-09
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016
5IMD
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Xanthomonas campestris Peroxiredoxin Q - Structure F4
分子名称: Bacterioferritin comigratory protein, FORMIC ACID, OXYGEN ATOM, ...
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-06
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016
5IM9
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Xanthomonas campestris Peroxiredoxin Q - Structure F1
分子名称: Bacterioferritin comigratory protein, SODIUM ION
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-05
公開日2016-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016
5IMZ
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BU of 5imz by Molmil
Xanthomonas campestris Peroxiredoxin Q - Structure F7
分子名称: Bacterioferritin comigratory protein, CHLORIDE ION, FORMIC ACID, ...
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-07
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016
5IO2
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Xanthomonas campestris Peroxiredoxin Q - C48S mutant
分子名称: Bacterioferritin comigratory protein, PHOSPHATE ION, SODIUM ION
著者Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A.
登録日2016-03-08
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Peroxiredoxin Catalysis at Atomic Resolution.
Structure, 24, 2016

 

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