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6OBJ
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BU of 6obj by Molmil
Structure of a DNA-bound dimer extracted from filamentous SgrAI endonuclease in its activated form
分子名称: DNA (26-MER), MAGNESIUM ION, SgraIR restriction enzyme
著者Polley, S, Lyumkis, D, Horton, N.C.
登録日2019-03-20
公開日2020-02-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease.
Structure, 27, 2019
5EBZ
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BU of 5ebz by Molmil
Crystal structure of human IKK1
分子名称: 2,3-di-O-sulfo-alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-6)-2,4-di-O-sulfo-alpha-D-glucopyranose, 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide, Inhibitor of nuclear factor kappa-B kinase subunit alpha, ...
著者Polley, S, Passos, D, Huang, D, Biswas, T, Verma, I, Lyumkis, D, Ghosh, G.
登録日2015-10-20
公開日2016-11-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
4E3C
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BU of 4e3c by Molmil
X-ray crystal structure of human IKK2 in an active conformation
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit beta
著者Polley, S, Huang, D.B, Hauenstein, A.V, Ghosh, G, Huxford, T.
登録日2012-03-09
公開日2013-06-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献X-ray crystal structure of human IKK2 in an active conformation
Plos.Biol., 2013
8Q5H
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BU of 8q5h by Molmil
Human KMN network (outer kinetochore)
分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ...
著者Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S.
登録日2023-08-09
公開日2024-02-14
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of the human KMN complex and implications for regulation of its assembly.
Nat.Struct.Mol.Biol., 31, 2024
5TQW
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BU of 5tqw by Molmil
CryoEM reconstruction of human IKK1, open conformation 1
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
5TQX
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BU of 5tqx by Molmil
CryoEM reconstruction of human IKK1, intermediate conformation 2
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
5TQY
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BU of 5tqy by Molmil
CryoEM reconstruction of human IKK1, closed conformation 3
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit alpha
著者Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O.
登録日2016-10-24
公開日2016-11-09
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
7E4W
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BU of 7e4w by Molmil
Human Transcriptional Co-activator PC4 (C-terminal Domain) in space group P1211
分子名称: Activated RNA polymerase II transcriptional coactivator p15
著者Dev, A, Pandey, B, Basu, G.
登録日2021-02-15
公開日2021-09-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules.
Biochem.Biophys.Res.Commun., 578, 2021

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件を2024-11-06に公開中

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