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Choline Kinase alpha acts through a double-displacement kinetic mechanism involving enzyme isomerisation, as determined through enzyme and inhibitor kinetics and structural biology
分子名称:	(3R)-1-azabicyclo[2.2.2]oct-3-yl[bis(5-chlorothiophen-2-yl)]methanol, Choline kinase alpha, SULFATE ION
著者	Brown, K, Hudson, C, Charlton, P, Pollard, J.
登録日	2012-01-12
公開日	2013-04-17
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Kinetic and mechanistic characterisation of Choline Kinase-alpha. Biochim.Biophys.Acta, 1834, 2013

Cryo-EM structure of the human GS-GN complex in the inhibited state
分子名称:	Glycogen [starch] synthase, muscle, Isoform GN-1 of Glycogenin-1
著者	Marr, L, Zeqiraj, E.
登録日	2022-03-23
公開日	2022-06-22
実験手法	ELECTRON MICROSCOPY (2.62 Å)
主引用文献	Mechanism of glycogen synthase inactivation and interaction with glycogenin. Nat Commun, 13, 2022

Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Apo-structure.
分子名称:	1,2-ETHANEDIOL, beta-methylaspartase
著者	Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日	2001-11-12
公開日	2001-12-19
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J.Biol.Chem., 277, 2002

Crystal Structure of beta-methylaspartase from Clostridium tetanomorphum. Mg-complex.
分子名称:	1,2-ETHANEDIOL, MAGNESIUM ION, beta-methylaspartase
著者	Asuncion, M, Blankenfeldt, W, Barlow, J.N, Gani, D, Naismith, J.H.
登録日	2001-11-12
公開日	2001-12-19
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J.Biol.Chem., 277, 2002