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3U30
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BU of 3u30 by Molmil
Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin
分子名称: Heavy chain Fab, Light chain Fab, linear di-ubiquitin
著者Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F.
登録日2011-10-04
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.428 Å)
主引用文献Engineering and structural characterization of a linear polyubiquitin-specific antibody.
J.Mol.Biol., 418, 2012
7MFR
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BU of 7mfr by Molmil
Crystal Structure of a Fab fragment bound to peptide GGM
分子名称: Antibody fragment - Heavy Chain of fab, Antibody fragment - Light Chain of fab, GLY-GLY-MET, ...
著者Sudhamsu, J.
登録日2021-04-10
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W.
Nat Commun, 12, 2021
3OJ4
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BU of 3oj4 by Molmil
Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex
分子名称: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, Ubiquitin-conjugating enzyme E2 D1, ...
著者Bosanac, I, Hymowitz, S.G.
登録日2010-08-20
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
Mol.Cell, 40, 2010
3OJ3
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BU of 3oj3 by Molmil
Crystal structure of the A20 ZnF4 and ubiquitin complex
分子名称: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, ZINC ION
著者Bosanac, I, Hymowitz, S.G.
登録日2010-08-20
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-KB Signaling
Mol.Cell, 40, 2010
3NOB
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BU of 3nob by Molmil
Structure of K11-linked di-ubiquitin
分子名称: SULFATE ION, Ubiquitin
著者Dong, K.C, Matsumoto, M.L, Hymowitz, S.G.
登録日2010-06-25
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献K11-Linked Polyubiquitination in Cell Cycle Control Revealed by a K11 Linkage-Specific Antibody.
Mol.Cell, 39, 2010
3PTF
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BU of 3ptf by Molmil
X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1
著者Bosanac, I, Hymowitz, S.G.
登録日2010-12-02
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.
J.Mol.Biol., 408, 2011
7R7R
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BU of 7r7r by Molmil
Structure of Human Anaplastic Lymphoma Kinase Domain in complex with ((2~{R})-2-[5-[6-amino-5-[(1~{R})-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-3-pyridyl]-4-methyl-thiazol-2-yl]propane-1,2-diol)
分子名称: (2R)-2-[5-(6-amino-5-{(1R)-1-[2-(1,3-dihydro-2H-1,2,3-triazol-2-yl)-5-fluorophenyl]ethoxy}pyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol, ALK tyrosine kinase receptor
著者McTigue, M.
登録日2021-06-25
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.935 Å)
主引用文献Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Nat Cancer, 3, 2022
7R7K
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BU of 7r7k by Molmil
Structure of Human Anaplastic Lymphoma Kinase Domain in complex with (4-[6-amino-5-[(1~{R})-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-3-pyridyl]isoindolin-1-one)
分子名称: 4-(6-amino-5-{(1R)-1-[5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl]ethoxy}pyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one, ALK tyrosine kinase receptor
著者McTigue, M.
登録日2021-06-24
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.831 Å)
主引用文献Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Nat Cancer, 3, 2022
4JLP
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BU of 4jlp by Molmil
Crystal structure of R150K aquifex adenylate kinase mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase
著者Cho, Y.-J, Phung, L, Kern, D.
登録日2013-03-12
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.433 Å)
主引用文献The energy landscape of adenylate kinase during catalysis.
Nat.Struct.Mol.Biol., 22, 2015
4JLO
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BU of 4jlo by Molmil
Crystal structure of Aquifex adenylate kinase R150K mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase
著者Cho, Y.-J, Phung, L, Kern, D.
登録日2013-03-12
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The energy landscape of adenylate kinase during catalysis.
Nat.Struct.Mol.Biol., 22, 2015

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件を2024-07-10に公開中

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