2RCJ
 
 | | Solution structure of human Immunoglobulin M | | 分子名称: | IgA1 heavy chain, IgA1 light chain, J chain | | 著者 | Perkins, S.J, Nealis, A.S, Sutton, B.J, Feinstein, A. | | 登録日 | 2007-09-20 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation.
J.Mol.Biol., 221, 1991
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2ATY
 | | Complement receptor chimaeric conjugate CR2-Ig | | 分子名称: | Complement receptor chimeric conjugate CR2-Ig | | 著者 | Gilbert, H.E, Aslam, M, Guthridge, J.M, Holers, V.M, Perkins, S.J. | | 登録日 | 2005-08-26 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Extended Flexible Linker Structures in the Complement Chimaeric Conjugate CR2-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy.
J.Mol.Biol., 356, 2006
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1QOK
 | | MFE-23 AN ANTI-CARCINOEMBRYONIC ANTIGEN SINGLE-CHAIN FV ANTIBODY | | 分子名称: | MFE-23 RECOMBINANT ANTIBODY FRAGMENT | | 著者 | Boehm, M.K, Corper, A.L, Wan, T, Sohi, M.K, Sutton, B.J, Thornton, J.D, Keep, P.A, Chester, K.A, Begent, R.H.J, Perkins, S.J. | | 登録日 | 1999-11-11 | | 公開日 | 2000-11-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the Anti-Carcinoembryonic Antigen Single-Chain Fv Antibody Mfe-23 and a Model for Antigen Binding Based on Intermolecular Contacts
Biochem.J., 346, 2000
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2Q7Z
 | | Solution Structure of the 30 SCR domains of human Complement Receptor 1 | | 分子名称: | Complement receptor type 1 | | 著者 | Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J. | | 登録日 | 2007-06-08 | | 公開日 | 2007-10-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands
J.Mol.Biol., 375, 2008
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2QFG
 | | Solution Structure of the N-terminal SCR-1/5 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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6R2U
 | | Zinc-alpha2-Glycoprotein with a Fluorescent Dansyl C 11 Fatty Acid | | 分子名称: | 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, AZIDE ION, SULFATE ION, ... | | 著者 | Lau, A.M, Gor, J, Perkins, S.J, Coker, A.R, McDermott, L.C. | | 登録日 | 2019-03-18 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Crystal structure of zinc-alpha 2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding.
Biochem.J., 476, 2019
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3CHN
 | | Solution structure of human secretory IgA1 | | 分子名称: | Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component | | 著者 | Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J. | | 登録日 | 2008-03-10 | | 公開日 | 2008-12-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
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1IGA
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3CM9
 | | Solution Structure of Human SIgA2 | | 分子名称: | Immunoglobulin heavy chain, Immunoglobulin light chain, Secretory component | | 著者 | Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J. | | 登録日 | 2008-03-21 | | 公開日 | 2008-12-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The nonplanar secretory IgA2 and near planar secretory IgA1 solution structures rationalize their different mucosal immune responses.
J.Biol.Chem., 284, 2009
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2IC4
 | | Solution structure of the His402 allotype of the Factor H SCR6-SCR7-SCR8 fragment | | 分子名称: | Complement factor H | | 著者 | Fernando, A.N, Furtado, P.B, Gilbert, H.E, Clark, S.J, Day, A.J, Sim, R.B, Perkins, S.J. | | 登録日 | 2006-09-12 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin.
J.Mol.Biol., 368, 2007
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1E07
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2ESG
 | | Solution structure of the complex between immunoglobulin IgA1 and human serum albumin | | 分子名称: | Immunoglobulin A1 heavy chain, Immunoglobulin A1 light chain, Serum albumin | | 著者 | Almogren, A, Furtado, P.B, Sun, Z, Perkins, S.J, Kerr, M.A. | | 登録日 | 2005-10-26 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Purification, Properties and Extended Solution Structure of the Complex Formed between Human Immunoglobulin A1 and Human Serum Albumin by Scattering and Ultracentrifugation.
J.Mol.Biol., 356, 2006
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2OCW
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2GSX
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2QTJ
 | | Solution structure of human dimeric immunoglobulin A | | 分子名称: | Ig alpha-1 chain C region, Kappa light chain IgA1 | | 著者 | Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J. | | 登録日 | 2007-08-02 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy
J.Immunol., 180, 2008
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2QFH
 | | Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H. | | 分子名称: | Complement factor H | | 著者 | Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J. | | 登録日 | 2007-06-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | SOLUTION SCATTERING | | 主引用文献 | The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
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1NTJ
 | | Model of rat Crry determined by solution scattering, curve fitting and homology modelling | | 分子名称: | complement receptor related protein | | 著者 | Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J. | | 登録日 | 2003-01-30 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | The Extended Multidomain Solution Structures of the Complement Protein
Crry and its Chimeric Conjugate Crry-Ig by Scattering, Analytical
Ultracentrifugation and Constrained Modelling: Implications for Function and
Therapy
J.Mol.Biol., 329, 2003
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1NTL
 | | Model of mouse Crry-Ig determined by solution scattering, curve fitting and homology modelling | | 分子名称: | Complement component receptor 1-like protein,Ig gamma-1 chain C region secreted form | | 著者 | Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J. | | 登録日 | 2003-01-30 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | The extended multidomain solution structures of the complement protein Crry
and its chimaeric conjugate Crry-Ig by scattering, analytical ultracentrifugation
and constrained modelling: implications for function and therapy
J.Mol.Biol., 329, 2003
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5CKQ
 | | CUB1-EGF-CUB2 domains of rat MASP-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine protease 1, ... | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-15 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.704 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
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5CIS
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-13 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
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5CKM
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-15 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
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5CKN
 | | The CUB1-EGF-CUB2 domains of rat MBL-associated serine protease-2 (MASP-2) bound to Ca2+ | | 分子名称: | CALCIUM ION, Mannan-binding lectin serine peptidase 2 | | 著者 | Nan, R, Furze, C.M, Wright, D.W, Gor, J, Wallis, R, Perkins, S.J. | | 登録日 | 2015-07-15 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.
Structure, 25, 2017
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1R70
 | | Model of human IgA2 determined by solution scattering, curve fitting and homology modelling | | 分子名称: | Human IgA2(m1) Heavy Chain, Human IgA2(m1) Light Chain | | 著者 | Furtado, P.B, Whitty, P.W, Robertson, A, Eaton, J.T, Almogren, A, Kerr, M.A, Woof, J.M, Perkins, S.J. | | 登録日 | 2003-10-17 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | Solution Structure Determination of Monomeric Human IgA2 by X-ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Modelling: A Comparison with Monomeric Human IgA1.
J.Mol.Biol., 338, 2004
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1W0S
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1W0R
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