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5DD1
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BU of 5dd1 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
著者Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD0
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BU of 5dd0 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
著者Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
4QF1
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BU of 4qf1 by Molmil
Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2014-05-19
公開日2015-02-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
7UD6
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BU of 7ud6 by Molmil
Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)
分子名称: POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase
著者Ongpipattanakul, C, Nair, S.K.
登録日2022-03-18
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Designer installation of a substrate recruitment domain to tailor enzyme specificity.
Nat.Chem.Biol., 19, 2023
8CSA
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BU of 8csa by Molmil
Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
分子名称: Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2022-05-12
公開日2022-07-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
Science, 2021
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
分子名称: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
著者Manne, K, Nicely, N.I, Acharya, P.
登録日2020-07-13
公開日2020-12-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
6X2B
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BU of 6x2b by Molmil
SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X2C
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BU of 6x2c by Molmil
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
7M0J
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BU of 7m0j by Molmil
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer - asymmetric refinement
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2021-03-11
公開日2021-03-31
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity.
Biorxiv, 2021
6X2A
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BU of 6x2a by Molmil
SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X29
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BU of 6x29 by Molmil
SARS-CoV-2 rS2d Down State Spike Protein Trimer
分子名称: Spike glycoprotein
著者Henderson, R, Acharya, P.
登録日2020-05-20
公開日2020-05-27
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
8VLT
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BU of 8vlt by Molmil
Crystal structure of glycan-targeting antibody 2526 Fab bound to Mannose
分子名称: 2526 Fab Heavy Chain, 2526 Fab Light Chain, alpha-D-mannopyranose
著者Lindenberger, J, Acharya, P.
登録日2024-01-12
公開日2024-10-16
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Isolation and characterization of IgG3 glycan-targeting antibodies with exceptional cross-reactivity for diverse viral families.
Plos Pathog., 20, 2024
7BH8
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BU of 7bh8 by Molmil
3H4-Fab HLA-E-VL9 co-complex
分子名称: 3H4 Fab heavy chain, 3H4 Fab light chain, Beta-2-microglobulin, ...
著者Walters, L.C, Rozbesky, D.
登録日2021-01-10
公開日2022-04-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Commun Biol, 5, 2022
7LYK
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BU of 7lyk by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 2-RBD-up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYL
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BU of 7lyl by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the RBD-down conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYQ
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BU of 7lyq by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYO
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BU of 7lyo by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYP
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BU of 7lyp by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
7LYN
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BU of 7lyn by Molmil
South African (B.1.351) SARS-CoV-2 spike protein variant (S-GSAS-B.1.351) in the 1-RBD-up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-07
公開日2021-03-31
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
8SAW
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BU of 8saw by Molmil
CryoEM structure of DH270.UCA.G57R-CH848.10.17DT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp120A, CH848.3.D0949.10.17chim.6R.SOSIP.664 gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAN
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BU of 8san by Molmil
CryoEM structure of VRC01-CH848.0836.10
分子名称: CH848.0836.10 gp120, CH848.0836.10 gp41, VCR01 variable heavy chain, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-01
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAQ
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BU of 8saq by Molmil
CryoEM structure of DH270.6-CH848.0526.25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.0526.25 gp120, CH848.0526.25 gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-01
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAU
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BU of 8sau by Molmil
CryoEM structure of DH270.4-CH848.10.17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SB2
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BU of 8sb2 by Molmil
CryoEM structure of DH270.I2-CH848.10.17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SB0
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BU of 8sb0 by Molmil
CryoEM structure of DH270.I4.6-CH848.10.17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023

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