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3FCK
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BU of 3fck by Molmil
Complex of UNG2 and a fragment-based design inhibitor
分子名称: 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
3FCI
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BU of 3fci by Molmil
Complex of UNG2 and a fragment-based designed inhibitor
分子名称: 3-{(E)-[(3-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}propoxy)imino]methyl}benzoic acid, SODIUM ION, THIOCYANATE ION, ...
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
3FCL
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BU of 3fcl by Molmil
Complex of UNG2 and a fragment-based designed inhibitor
分子名称: 3-{[(4-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}butyl)amino]methyl}benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
3FCF
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BU of 3fcf by Molmil
Complex of UNG2 and a fragment-based designed inhibitor
分子名称: 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
2OXM
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BU of 2oxm by Molmil
Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping
分子名称: DNA (5'-D(*AP*AP*AP*GP*AP*TP*(4MF)P*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*AP*TP*CP*TP*T)-3'), Uracil-DNA glycosylase
著者Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M.
登録日2007-02-20
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Nature, 449, 2007
2OYT
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BU of 2oyt by Molmil
Crystal Structure of UNG2/DNA(TM)
分子名称: DNA strand1, DNA strand2, Uracil-DNA glycosylase
著者Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M.
登録日2007-02-22
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Nature, 449, 2007

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件を2024-08-21に公開中

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