1L8L
 
 | | Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase | | 分子名称: | D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, L-3-phosphoserine phosphatase | | 著者 | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | | 登録日 | 2002-03-21 | | 公開日 | 2003-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
J.Biol.Chem., 277, 2002
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1L8O
 | | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase | | 分子名称: | L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE | | 著者 | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | | 登録日 | 2002-03-21 | | 公開日 | 2003-04-01 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
J.Biol.Chem., 277, 2002
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1GP8
 | | NMR SOLUTION STRUCTURE OF THE COAT PROTEIN-BINDING DOMAIN OF BACTERIOPHAGE P22 SCAFFOLDING PROTEIN | | 分子名称: | PROTEIN (SCAFFOLDING PROTEIN) | | 著者 | Sun, Y, Parker, M.H, Weigele, P, Casjens, S, Prevelige Jr, P.E, Krishna, N.R. | | 登録日 | 1999-05-11 | | 公開日 | 1999-05-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
J.Mol.Biol., 297, 2000
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1EKU
 | | CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA | | 分子名称: | Interferon gamma, SULFATE ION | | 著者 | Landar, A, Curry, B, Parker, M.H, DiGiacomo, R, Indelicato, S.R, Walter, M.R. | | 登録日 | 2000-03-09 | | 公開日 | 2000-09-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.
J.Mol.Biol., 299, 2000
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2GP8
 | | NMR SOLUTION STRUCTURE OF THE COAT PROTEIN-BINDING DOMAIN OF BACTERIOPHAGE P22 SCAFFOLDING PROTEIN | | 分子名称: | PROTEIN (SCAFFOLDING PROTEIN) | | 著者 | Sun, Y, Parker, M.H, Weigele, P, Casjens, S, Prevelige Jr, P.E, Krishna, N.R. | | 登録日 | 1999-05-11 | | 公開日 | 1999-05-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
J.Mol.Biol., 297, 2000
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1DHS
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5C37
 | | Structure of the beta-ketoacyl reductase domain of human fatty acid synthase bound to a spiro-imidazolone inhibitor | | 分子名称: | 6-{[(3R)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-5-[4-(1-methyl-1H-indazol-5-yl)phenyl]-4,6-diazaspiro[2.4]hept-4-en-7-one, CHLORIDE ION, Fatty acid synthase, ... | | 著者 | Schubert, C, Milligan, C.M, Vo, K, Grasberger, B. | | 登録日 | 2015-06-17 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy.
Bioorg.Med.Chem.Lett., 28, 2018
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2Q11
 | | Structure of BACE complexed to compound 1 | | 分子名称: | 3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE, Beta-secretase 1 | | 著者 | Sharff, A.J. | | 登録日 | 2007-05-23 | | 公開日 | 2007-08-14 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
J.Med.Chem., 50, 2007
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2Q15
 | | Structure of BACE complexed to compound 3a | | 分子名称: | (4S)-4-(2-AMINO-6-PHENOXYQUINAZOLIN-3(4H)-YL)-N,4-DICYCLOHEXYL-N-METHYLBUTANAMIDE, Beta-secretase 1 | | 著者 | Sharff, A.J. | | 登録日 | 2007-05-23 | | 公開日 | 2007-08-14 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
J.Med.Chem., 50, 2007
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1JUO
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2JC2
 | | The crystal structure of the natural F112L human sorcin mutant | | 分子名称: | SORCIN, SULFATE ION | | 著者 | Franceschini, S, Ilari, A, Colotti, G, Chiancone, E. | | 登録日 | 2006-12-19 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular Basis for the Impaired Function of the Natural F112L Sorcin Mutant: X-Ray Crystal Structure, Calcium Affinity, and Interaction with Annexin Vii and the Ryanodine Receptor.
Faseb J., 22, 2008
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1LK3
 | | ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT | | 分子名称: | 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10 | | 著者 | Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R. | | 登録日 | 2002-04-23 | | 公開日 | 2002-07-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography.
Structure, 10, 2002
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