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4M1W
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BU of 4m1w by Molmil
Crystal Structure of small molecule vinylsulfonamide covalently bound to K-Ras G12C
分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, MAGNESIUM ION, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-04
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4L8G
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BU of 4l8g by Molmil
Crystal Structure of K-Ras G12C, GDP-bound
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-06-17
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.521 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4L9W
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BU of 4l9w by Molmil
Crystal Structure of H-Ras G12C, GMPPNP-bound
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-06-18
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4L9S
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BU of 4l9s by Molmil
Crystal Structure of H-Ras G12C, GDP-bound
分子名称: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-06-18
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.606 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M1Y
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BU of 4m1y by Molmil
Crystal Structure of small molecule vinylsulfonamide 15 covalently bound to K-Ras G12C
分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[N-(5,7-dichloro-2,1,3-benzothiadiazol-4-yl)glycyl]piperidin-4-yl}ethanesulfonamide
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-04
公開日2013-11-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LYH
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BU of 4lyh by Molmil
Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, N-{1-[N-(4-chloro-5-iodo-2-methoxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-31
公開日2013-11-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.371 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M22
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BU of 4m22 by Molmil
Crystal Structure of small molecule acrylamide 16 covalently bound to K-Ras G12C
分子名称: 1-{4-[(2,4-dichlorophenoxy)acetyl]piperazin-1-yl}propan-1-one, GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-05
公開日2013-11-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LPK
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BU of 4lpk by Molmil
Crystal Structure of K-Ras WT, GDP-bound
分子名称: CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-16
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LUC
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BU of 4luc by Molmil
Crystal Structure of small molecule disulfide 6 bound to K-Ras G12C
分子名称: CALCIUM ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-25
公開日2013-11-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M1S
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BU of 4m1s by Molmil
Crystal Structure of small molecule vinylsulfonamide 13 covalently bound to K-Ras G12C
分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[N-(2,4-dichlorophenyl)glycyl]piperidin-4-yl}ethanesulfonamide
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-04
公開日2013-11-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M1T
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BU of 4m1t by Molmil
Crystal Structure of small molecule vinylsulfonamide 14 covalently bound to K-Ras G12C
分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-{1-[(2,4-dichlorophenoxy)acetyl]piperidin-4-yl}ethanesulfonamide
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-04
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LRW
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BU of 4lrw by Molmil
Crystal Structure of K-Ras G12C (cysteine-light), GDP-bound
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-21
公開日2013-11-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LYJ
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BU of 4lyj by Molmil
Crystal Structure of small molecule vinylsulfonamide 9 covalently bound to K-Ras G12C, alternative space group
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-31
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.927 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LV6
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BU of 4lv6 by Molmil
Crystal Structure of small molecule disulfide 4 covalently bound to K-Ras G12C
分子名称: 1-[(2,4-dichlorophenoxy)acetyl]-N-(2-sulfanylethyl)piperidine-4-carboxamide, CALCIUM ION, GTPase KRas, ...
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-26
公開日2013-11-27
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M1O
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BU of 4m1o by Molmil
Crystal Structure of small molecule vinylsulfonamide 7 covalently bound to K-Ras G12C
分子名称: GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase, N-(1-{[(5,7-dichloro-2,2-dimethyl-1,3-benzodioxol-4-yl)oxy]acetyl}piperidin-4-yl)ethanesulfonamide
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-03
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.571 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4LYF
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BU of 4lyf by Molmil
Crystal Structure of small molecule vinylsulfonamide 8 covalently bound to K-Ras G12C
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, N-{1-[N-(4,5-dichloro-2-hydroxyphenyl)glycyl]piperidin-4-yl}ethanesulfonamide
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-07-31
公開日2013-11-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.568 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4M21
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BU of 4m21 by Molmil
Crystal Structure of small molecule acrylamide 11 covalently bound to K-Ras G12C
分子名称: 1-(4-{[(4,5-dichloro-2-methoxyphenyl)amino]acetyl}piperazin-1-yl)propan-1-one, GUANOSINE-5'-DIPHOSPHATE, K-Ras GTPase
著者Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M.
登録日2013-08-05
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
4W7G
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BU of 4w7g by Molmil
Crystal Structure of the Dynein Light Intermediate Chain's Conserved Domain
分子名称: Dynein Light Intermediate Chain
著者Schroeder, C.M, Ekiert, D.C, Vale, R.D.
登録日2014-08-22
公開日2014-10-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region.
Elife, 3, 2014

226707

件を2024-10-30に公開中

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