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1MBU
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Crystal Structure Analysis of ClpSN heterodimer
分子名称: ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ...
著者Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D.
登録日2002-08-03
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
1MBV
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CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM
分子名称: ATP-Dependent clp Protease ATP-Binding Subunit clp A, Protein yljA
著者Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D.
登録日2002-08-03
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of AAA+ Chaperone ClpA
J.Biol.Chem., 277, 2002
1MBX
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CRYSTAL STRUCTURE ANALYSIS OF ClpSN WITH TRANSITION METAL ION BOUND
分子名称: ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ...
著者Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D.
登録日2002-08-03
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
2ANE
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BU of 2ane by Molmil
Crystal structure of N-terminal domain of E.Coli Lon Protease
分子名称: ATP-dependent protease La
著者Li, M, Rasulova, F, Melnikov, E.E, Rotanova, T.V, Gustchina, A, Maurizi, M.R, Wlodawer, A.
登録日2005-08-11
公開日2005-11-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of the N-terminal domain of E. coli Lon protease.
Protein Sci., 14, 2005
2FZS
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BU of 2fzs by Molmil
Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site
分子名称: ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE, ...
著者Szyk, A, Maurizi, M.R.
登録日2006-02-10
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site.
J.Struct.Biol., 156, 2006
1R6B
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High resolution crystal structure of ClpA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ClpA protein, MAGNESIUM ION
著者Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L.
登録日2003-10-15
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
1TG6
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Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLYCEROL, ...
著者Kang, S.G, Maurizi, M.R, Thompson, M, Mueser, T, Ahvazi, B.
登録日2004-05-28
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
1K6K
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Crystal Structure of ClpA, an AAA+ Chaperone-like Regulator of ClpAP protease implication to the functional difference of two ATPase domains
分子名称: ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA
著者Guo, F, Maurizi, M.R, Esser, L, Xia, D.
登録日2001-10-16
公開日2002-09-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease
J.Biol.Chem., 277, 2002
1KSF
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Crystal Structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease: Structural basis of differences in Function of the Two AAA+ ATPase domains
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA, ISOPROPYL ALCOHOL, ...
著者Guo, F, Maurizi, M.R, Esser, L, Xia, D.
登録日2002-01-12
公開日2002-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease
J.Biol.Chem., 277, 2002
1QZM
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alpha-domain of ATPase
分子名称: ATP-dependent protease La
著者Botos, I, Melnikov, E.E, Cherry, S, Khalatova, A.G, Rasulova, F.S, Tropea, J.E, Maurizi, M.R, Rotanova, T.V, Gustchina, A, Wlodawer, A.
登録日2003-09-17
公開日2004-05-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the AAA+ alpha domain of E. coli Lon protease at 1.9A resolution.
J.Struct.Biol., 146
1RRE
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Crystal structure of E.coli Lon proteolytic domain
分子名称: ATP-dependent protease La, SULFATE ION
著者Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Rasulova, F, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A.
登録日2003-12-08
公開日2004-02-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site
J.Biol.Chem., 279, 2004
1R6Q
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ClpNS with fragments
分子名称: ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ...
著者Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L.
登録日2003-10-16
公開日2005-02-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
1R6O
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ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS
分子名称: ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ...
著者Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L.
登録日2003-10-15
公開日2005-02-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone
J.Struct.Biol., 146, 2004
1R6C
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BU of 1r6c by Molmil
High resolution structure of ClpN
分子名称: ATP-dependent Clp protease ATP-binding subunit clpA
著者Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L.
登録日2003-10-15
公開日2005-02-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone
J.Struct.Biol., 146, 2004
1RR9
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Catalytic domain of E.coli Lon protease
分子名称: ATP-dependent protease La, SULFATE ION
著者Botos, I, Melnikov, E.E, Cherry, S, Tropea, J.E, Khalatova, A.G, Dauter, Z, Maurizi, M.R, Rotanova, T.V, Wlodawer, A, Gustchina, A.
登録日2003-12-08
公開日2003-12-23
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site
J.Biol.Chem., 279, 2004
5E0S
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BU of 5e0s by Molmil
crystal structure of the active form of the proteolytic complex clpP1 and clpP2
分子名称: ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2
著者LI, M, Wlodawer, A, Maurizi, M.
登録日2015-09-29
公開日2016-02-17
最終更新日2016-04-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
5DZK
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Crystal structure of the active form of the proteolytic complex clpP1 and clpP2
分子名称: ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, BEZ-LEU-LEU
著者LI, M, Wlodawer, A, Maurizi, M.
登録日2015-09-25
公開日2016-02-17
最終更新日2016-04-13
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
3LJC
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BU of 3ljc by Molmil
Crystal structure of Lon N-terminal domain.
分子名称: ATP-dependent protease La
著者Li, M, Gustchina, A, Dauter, Z, Wlodawer, A.
登録日2010-01-26
公開日2010-07-21
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the N-terminal fragment of Escherichia coli Lon protease
Acta Crystallogr.,Sect.D, 66, 2010
3MT6
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Structure of ClpP from Escherichia coli in complex with ADEP1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACYLDEPSIPEPTIDE 1, ATP-dependent Clp protease proteolytic subunit
著者Chung, Y.S.
登録日2010-04-30
公開日2010-11-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.
Chem.Biol., 17, 2010
5VZ2
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Structure of ClpP from Staphylococcus aureus in complex with Acyldepsipeptide
分子名称: ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide
著者Griffith, E.C, Lee, R.E.
登録日2017-05-26
公開日2017-06-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 2019
5W18
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Staphylococcus aureus ClpP in complex with (S)-N-((2R,6S,8aS,14aS,20S,23aS)-2,6-dimethyl-5,8,14,19,23-pentaoxooctadecahydro-1H,5H,14H,19H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1]oxa[4,7,10,13]tetraazacyclohexadecin-20-yl)-3-phenyl-2-(3-phenylureido)propanamide
分子名称: 9V7-PHE-SER-PRO-YCP-ALA-MP8, ATP-dependent Clp protease proteolytic subunit
著者Lee, R.E, Griffith, E.C.
登録日2017-06-02
公開日2017-08-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 2019
3K1J
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Crystal structure of Lon protease from Thermococcus onnurineus NA1
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Cha, S.S, An, Y.J.
登録日2009-09-28
公開日2010-09-22
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber
Embo J., 29, 2010
6CFD
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ADEP4 bound to E. faecium ClpP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, N-[(6aS,12S,15aS,17R,21R,23aS)-17,21-dimethyl-6,11,15,20,23-pentaoxooctadecahydro-2H,6H,11H,15H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13]oxatetraazacyclohexadecin-12-yl]-3,5-difluoro-Nalpha-[(2E)-hept-2-enoyl]-L-phenylalaninamide
著者Lee, R.E, Griffith, E.C.
登録日2018-02-14
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献In VivoandIn VitroEffects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.
Antimicrob. Agents Chemother., 62, 2018
1HT1
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Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU
分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK LOCUS HSLU, HEAT SHOCK LOCUS HSLV
著者Wang, J, Song, J.J, Seong, I.S, Franklin, M.C, Kamtekar, S, Eom, S.H, Chung, C.H.
登録日2000-12-27
公開日2001-11-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU.
Structure, 9, 2001
1HT2
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Nucleotide-Dependent Conformational Changes in a Protease-Associated ATPase HslU
分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK LOCUS HSLU, HEAT SHOCK LOCUS HSLV
著者Wang, J, Song, J.J, Seong, I.S, Franklin, M.C, Kamtekar, S, Eom, S.H, Chung, C.H.
登録日2000-12-27
公開日2001-11-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU.
Structure, 9, 2001

 

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