5FTG
| Human choline kinase a1 in complex with compound 1-[[4-[2-[4-[[4-(dimethylamino)pyridin-1- yl]methyl]phenoxy]ethoxy]phenyl]methyl]-N,N- dimethyl-pyridin-4-amine (compound 10a) | 分子名称: | 1,2-ETHANEDIOL, 1-[[4-[2-[4-[[4-(dimethylamino)pyridin-1-yl]methyl]phenoxy]ethoxy]phenyl]methyl]-N,N-dimethyl-pyridin-4-amine, CHOLINE KINASE ALPHA | 著者 | Schiaffino-Ortega, S, Baglioni, E, Mariotto, E, Bortolozzi, R, Serran-Aguilera, L, Rios-Marco, P, Carrasco-Jimenez, M.P, Gallo, M.A, Hurtado-Guerrero, R, Marco, C, Basso, G, Viola, G, Entrena, A, Lopez-Cara, L.C. | 登録日 | 2016-01-13 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Design, Synthesis, Crystallization and Biological Evaluation of New Symmetrical Biscationic Compounds as Selective Inhibitors of Human Choline Kinase Alpha1 (Chokalpha1) Sci.Rep., 6, 2016
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4CG9
| Human choline kinase a1 in complex with compound 12 | 分子名称: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[(4-phenylphenyl)methyl]pyridin-1-ium-4-amine | 著者 | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | 登録日 | 2013-11-21 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
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4CGA
| Human choline kinase a1 in complex with compound 5 | 分子名称: | CHOLINE KINASE ALPHA, N,N-dimethyl-1-[[4-(2-phenylethyl)phenyl]methyl]pyridin-1-ium-4-amine | 著者 | Rubio-Ruiz, B, Figuerola-Conchas, A, Ramos-Torrecillas, J, Capitan-Canadas, F, Rios-Marco, P, Carrasco, M.P, Gallo, M.A, Espinosa, A, Marco, C, Concepcion, C, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | 登録日 | 2013-11-21 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
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4CG8
| Human choline kinase a1 in complex with compound 14 | 分子名称: | 1-benzyl-4-(dimethylamino)pyridinium, 4-[(4-chlorophenyl)(methyl)amino]-1-{4-[4-(4-{[4-(dimethylamino)pyridinium-1-yl]methyl}phenyl)butyl]benzyl}pyridinium, CHOLINE KINASE ALPHA | 著者 | Rubio-Ruiz, B, Figuerola-Conchas, A, Entrena-Guadix, A, Hurtado-Guerrero, R, Conejo-Garcia, A. | 登録日 | 2013-11-21 | 公開日 | 2014-01-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of a New Binding Site on Human Choline Kinase A1: Design, Synthesis, Crystallographic Studies and Biological Evaluation of Asymmetrical Bispyridinium Derivatives J.Med.Chem., 57, 2014
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1IV5
| New Crystal Form of Human CD81 Large Extracellular Loop. | 分子名称: | CD81 antigen | 著者 | Kitadokoro, K, Bolognesi, M, Grandi, G, Marco, P, Galli, G, Petracca, R, Fabiana, F. | 登録日 | 2002-03-14 | 公開日 | 2003-01-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Subunit Association and Conformational Flexibility in the Head-subdomain of Human CD81 Large Extracellular Loop. Biol.Chem., 383, 2002
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5H7U
| NMR structure of eIF3 36-163 | 分子名称: | Eukaryotic translation initiation factor 3 subunit C | 著者 | Nagata, T, Obayashi, E. | 登録日 | 2016-11-21 | 公開日 | 2017-05-31 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5. Cell Rep, 18, 2017
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3J81
| CryoEM structure of a partial yeast 48S preinitiation complex | 分子名称: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | 著者 | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | 登録日 | 2014-08-29 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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3J80
| CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | 分子名称: | 18S rRNA, MAGNESIUM ION, RACK1, ... | 著者 | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | 登録日 | 2014-08-28 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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2RVH
| NMR structure of eIF1 | 分子名称: | Eukaryotic translation initiation factor eIF-1 | 著者 | Nagata, T, Obayashi, E, Asano, K. | 登録日 | 2015-10-16 | 公開日 | 2016-10-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5 Cell Rep, 18, 2017
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