6NHA
 
 | | Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | | 著者 | Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K. | | 登録日 | 2018-12-21 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | | 主引用文献 | Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Sci Adv, 5, 2019
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3H75
 | | Crystal Structure of a Periplasmic Sugar-binding protein from the Pseudomonas fluorescens | | 分子名称: | GLYCEROL, Periplasmic sugar-binding domain protein, SULFATE ION | | 著者 | Kumaran, D, Mahmood, A, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-04-24 | | 公開日 | 2009-05-12 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of a Periplasmic Sugar-binding protein from the Pseudomonas fluorescens
To be Published
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6ARY
 | | Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor | | 分子名称: | (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | | 著者 | Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. | | 登録日 | 2017-08-23 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.257 Å) | | 主引用文献 | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
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6ARX
 | | Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, CHLORIDE ION, ... | | 著者 | Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. | | 登録日 | 2017-08-23 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
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3EUW
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3DTY
 | | Crystal structure of an Oxidoreductase from Pseudomonas syringae | | 分子名称: | MAGNESIUM ION, Oxidoreductase, Gfo/Idh/MocA family | | 著者 | Eswaramoorthy, S, Mahmood, A, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-07-16 | | 公開日 | 2008-08-05 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of an Oxidoreductase from Pseudomonas syringae
To be Published
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2JRC
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6VWA
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6VW9
 | | C-terminal regulatory domain of the chloride transporter KCC-1 from C. elegans, proteolyzed during crystallization | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, K+/Cl-Cotransporter | | 著者 | Zimanyi, C.M, Cheung, J. | | 登録日 | 2020-02-19 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the Regulatory Cytosolic Domain of a Eukaryotic Potassium-Chloride Cotransporter.
Structure, 28, 2020
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4D2S
 | | Human TTK in complex with a Dyrk1B inhibitor | | 分子名称: | DUAL SPECIFICITY PROTEIN KINASE TTK, N-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | | 著者 | Debreczeni, J.E, Kettle, J.G, Ballard, P, Bardelle, C, Butterworth, S, Colclough, N, Critchlow, S.E, Fairley, G, Fillery, S, Graham, M.A, Goodwin, L, Guichard, S, Hudson, K, Mahmood, A, Vincent, J, Ward, R.A, Whittaker, D. | | 登録日 | 2014-05-12 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors to Explore a Mek Resistance Hypothesis.
J.Med.Chem., 58, 2015
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4D2R
 | | Human IGF in complex with a Dyrk1B inhibitor | | 分子名称: | CHLORIDE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR, N-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | | 著者 | Debreczeni, J.E, Kettle, J.G, Ballard, P, Bardelle, C, Butterworth, S, Colclough, N, Critchlow, S.E, Fairley, G, Fillery, S, Graham, M.A, Goodwin, L, Guichard, S, Hudson, K, Mahmood, A, Vincent, J, Ward, R.A, Whittaker, D. | | 登録日 | 2014-05-12 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors to Explore a Mek Resistance Hypothesis.
J.Med.Chem., 58, 2015
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