4URM
 
 | | Crystal Structure of Staph GyraseB 24kDa in complex with Kibdelomycin | | 分子名称: | (1R,4aS,5S,6S,8aR)-5-{[(5S)-1-(3-O-acetyl-4-O-carbamoyl-6-deoxy-2-O-methyl-alpha-L-talopyranosyl)-4-hydroxy-2-oxo-5-(propan-2-yl)-2,5-dihydro-1H-pyrrol-3-yl]carbonyl}-6-methyl-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl 2,6-dideoxy-3-C-[(1S)-1-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}ethyl]-beta-D-ribo-hexopyranoside, DNA GYRASE SUBUNIT B | | 著者 | Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. | | 登録日 | 2014-06-30 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
Acs Chem.Biol., 9, 2014
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4MJ7
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8DIN
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8DJ7
 | | The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin gamma Fc receptor I, Ig gamma-1 Fc chain, ... | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2022-06-30 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.
Front Immunol, 14, 2023
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8DIR
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6KYL
 | | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 in Complex with (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate | | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, Mitochondrial distribution and morphology protein 35, Protein UPS1, ... | | 著者 | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | | 登録日 | 2019-09-19 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | | 主引用文献 | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1.
Commun Biol, 3, 2020
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4URL
 | | Crystal Structure of Staph ParE43kDa in complex with KBD | | 分子名称: | (1R,4aS,5S,6S,8aR)-5-{[(5S)-1-(3-O-acetyl-4-O-carbamoyl-6-deoxy-2-O-methyl-alpha-L-talopyranosyl)-4-hydroxy-2-oxo-5-(propan-2-yl)-2,5-dihydro-1H-pyrrol-3-yl]carbonyl}-6-methyl-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl 2,6-dideoxy-3-C-[(1S)-1-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}ethyl]-beta-D-ribo-hexopyranoside, DNA TOPOISOMERASE IV, B SUBUNIT | | 著者 | Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. | | 登録日 | 2014-06-30 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
Acs Chem.Biol., 9, 2014
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4URN
 | | Crystal Structure of Staph ParE 24kDa in complex with Novobiocin | | 分子名称: | DNA TOPOISOMERASE IV, B SUBUNIT, NOVOBIOCIN | | 著者 | Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. | | 登録日 | 2014-07-01 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
Acs Chem.Biol., 9, 2014
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7WVS
 | | The structure of FinI complex with SAM | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Methyltransf_2 domain-containing protein, ... | | 著者 | Lu, J, Zhou, J. | | 登録日 | 2022-02-11 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The structure of FinI complex with SAM
To Be Published
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4X4M
 | | Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2014-12-03 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.485 Å) | | 主引用文献 | Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2CJS
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ... | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
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2CJT
 | | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A | | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | | 登録日 | 2006-04-06 | | 公開日 | 2006-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
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5JQM
 | | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 1.5 Angstroms Resolution | | 分子名称: | Protein UPS1, mitochondrial,Mitochondrial distribution and morphology protein 35 | | 著者 | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | | 登録日 | 2016-05-05 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1
Commun Biol, 2020
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5JQL
 | | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 2.9 Angstroms Resolution | | 分子名称: | Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial | | 著者 | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | | 登録日 | 2016-05-05 | | 公開日 | 2017-07-12 | | 最終更新日 | 2020-09-02 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1
Commun Biol, 2020
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4R3Q
 | | Crystal structure of SYCE3 | | 分子名称: | Synaptonemal complex central element protein 3 | | 著者 | Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y. | | 登録日 | 2014-08-17 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Structural insight into the central element assembly of the synaptonemal complex
Sci Rep, 4, 2014
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4URO
 | | Crystal Structure of Staph GyraseB 24kDa in complex with Novobiocin | | 分子名称: | DNA GYRASE SUBUNIT B, NOVOBIOCIN | | 著者 | Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. | | 登録日 | 2014-07-01 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
Acs Chem.Biol., 9, 2014
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1MX8
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1MX7
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1Z28
 | | Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF) | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Phenol-sulfating phenol sulfotransferase 1 | | 著者 | Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W. | | 登録日 | 2005-03-07 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
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1Z29
 | | Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF) | | 分子名称: | ACETIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, ... | | 著者 | Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W. | | 登録日 | 2005-03-07 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
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1KMD
 | | SOLUTION STRUCTURE OF THE VAM7P PX DOMAIN | | 分子名称: | Vacuolar morphogenesis protein VAM7 | | 著者 | Lu, J, Garcia, J, Dulubova, I, Sudhof, T.C, Rizo, J. | | 登録日 | 2001-12-14 | | 公開日 | 2002-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Vam7p PX domain.
Biochemistry, 41, 2002
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1ZUB
 | | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide | | 分子名称: | ELKS1b, Regulating synaptic membrane exocytosis protein 1 | | 著者 | Lu, J, Li, H, Wang, Y, Sudhof, T.C, Rizo, J. | | 登録日 | 2005-05-30 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide
J.Mol.Biol., 352, 2005
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2G9E
 | | Protonation-mediated structural flexibility in the F conjugation regulatory protein, TRAM | | 分子名称: | Protein traM | | 著者 | Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N. | | 登録日 | 2006-03-06 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
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5GXO
 | | Discovery of a compound that activates SIRT3 to deacetylate Manganese Superoxide Dismutase | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Lu, J, Li, J, Wu, M, Wang, J, Xia, Q. | | 登録日 | 2016-09-19 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
Free Radic. Biol. Med., 112, 2017
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2G7O
 | | Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM | | 分子名称: | Protein traM | | 著者 | Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N. | | 登録日 | 2006-02-28 | | 公開日 | 2006-06-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
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