2J23
 
 | | Cross-reactivity and crystal structure of Malassezia sympodialis Thioredoxin (Mala s 13), a member of a new pan-allergen family | | 分子名称: | THIOREDOXIN | | 著者 | Limacher, A, Glaser, A.G, Meier, C, Scapozza, L, Crameri, R. | | 登録日 | 2006-08-16 | | 公開日 | 2006-11-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family.
J Immunol., 178, 2007
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2C3B
 | | The Crystal Structure of Aspergillus fumigatus Cyclophilin reveals 3D Domain Swapping of a Central Element | | 分子名称: | PPIASE, SULFATE ION | | 著者 | Limacher, A, Kloer, D.P, Fluckiger, S, Folkers, G, Crameri, R, Scapozza, L. | | 登録日 | 2005-10-05 | | 公開日 | 2006-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Crystal Structure of Aspergillus Fumigatus Cyclophilin Reveals 3D Domain Swapping of a Central Element
Structure, 14, 2006
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2CFE
 | | The 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | | 分子名称: | ALANINE, ALLERGEN, GLYCEROL, ... | | 著者 | Limacher, A, Glaser, A.G, Fluckiger, S, Scheynius, A, Scapozza, L, Crameri, R. | | 登録日 | 2006-02-20 | | 公開日 | 2006-02-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family.
Biochem. J., 396, 2006
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6OLA
 | | Structure of the PCV2d virus-like particle | | 分子名称: | Capsid protein, DNA (5'-D(P*CP*CP*GP*G)-3') | | 著者 | Khayat, R, Wen, K, Alimova, A, Galarza, J, Gottlieb, P. | | 登録日 | 2019-04-16 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural characterization of the PCV2d virus-like particle at 3.3 angstrom resolution reveals differences to PCV2a and PCV2b capsids, a tetranucleotide, and an N-terminus near the icosahedral 3-fold axes.
Virology, 537, 2019
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5WBE
 | | COX-1:MOFEZOLAC COMPLEX STRUCTURE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mofezolac, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Cingolani, G, Panella, A, Perrone, M.G, Vitale, P, Smith, W.L, Scilimati, A. | | 登録日 | 2017-06-28 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6).
Eur J Med Chem, 138, 2017
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7JXT
 | | Ovine COX-1 in complex with the subtype-selective derivative 2a | | 分子名称: | 2-[4,5-bis(2-chlorophenyl)-1H-imidazol-2-yl]-6-(prop-2-en-1-yl)phenyl methoxyacetate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ko, Y, Iaselli, M, Miciaccia, M, Friedrich, L, Schneider, G, Scilimati, A, Cingolani, G. | | 登録日 | 2020-08-27 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design.
Adv Sci, 8, 2021
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6Y3C
 | | Human COX-1 Crystal Structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Prostaglandin G/H synthase 1, ... | | 著者 | Miciaccia, M, Belviso, B.D, Iaselli, M, Ferorelli, S, Perrone, M.G, Caliandro, R, Scilimati, A. | | 登録日 | 2020-02-18 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.361 Å) | | 主引用文献 | Three-dimensional structure of human cyclooxygenase (hCOX)-1.
Sci Rep, 11, 2021
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5U6X
 | | COX-1:P6 COMPLEX STRUCTURE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5-chlorofuran-2-yl)-5-methyl-4-phenyl-1,2-oxazole, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Cingolani, G, Panella, A, Perrone, M.G, Vitale, P, Smith, W.L, Scilimati, A. | | 登録日 | 2016-12-09 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6).
Eur J Med Chem, 138, 2017
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4L9M
 | | Autoinhibited state of the Ras-specific exchange factor RasGRP1 | | 分子名称: | CITRIC ACID, GLYCEROL, RAS guanyl-releasing protein 1, ... | | 著者 | Iwig, J.S, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J.G, Wemmer, D.E, Roose, J.P, Kuriyan, J. | | 登録日 | 2013-06-18 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
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4L9U
 | | Structure of C-terminal coiled coil of RasGRP1 | | 分子名称: | GLYCEROL, RAS guanyl-releasing protein 1, SULFATE ION | | 著者 | Iwig, J.S, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J.G, Wemmer, D.E, Roose, J.P, Kuriyan, J. | | 登録日 | 2013-06-18 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6014 Å) | | 主引用文献 | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
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2KDC
 | | NMR Solution Structure of E. coli diacylglycerol kinase (DAGK) in DPC micelles | | 分子名称: | Diacylglycerol kinase | | 著者 | Van Horn, W.D, Kim, H, Ellis, C.D, Hadziselimovic, A, Sulistijo, E.S, Karra, M.D, Tian, C, Sonnichsen, F.D, Sanders, C.R. | | 登録日 | 2009-01-06 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase
Science, 324, 2009
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2MA2
 | | Solution structure of RasGRP2 EF hands bound to calcium | | 分子名称: | RAS guanyl-releasing protein 2 | | 著者 | Kuriyan, J, Iwig, J, Vercoulen, Y, Das, R, Barros, T, Limnander, A, Che, Y, Pelton, J, Wemmer, D, Roose, J. | | 登録日 | 2013-06-24 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1.
Elife, 2, 2013
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2LP1
 | | The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99) | | 分子名称: | C99 | | 著者 | Barrett, P.J, Song, Y, Van Horn, W.D, Hustedt, E.J, Schafer, J.M, Hadziselimovic, A, Beel, A.J, Sanders, C.R. | | 登録日 | 2012-01-30 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol.
Science, 336, 2012
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3J05
 | | Three-dimensional structure of Dengue virus serotype 1 complexed with HMAb 14c10 Fab | | 分子名称: | envelope protein | | 著者 | Teoh, E.P, Kukkaro, P, Teo, E.W, Lim, A, Tan, T.T, Shi, P.Y, Yip, A, Schul, W, Leo, Y.S, Chan, S.H, Smith, K.G.C, Ooi, E.E, Kemeny, D.M, Ng, G, Ng, M.L, Alonso, S, Fisher, D, Hanson, B, Lok, S.M, MacAry, P.A. | | 登録日 | 2011-04-01 | | 公開日 | 2012-07-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | The structural basis for serotype-specific neutralization of dengue virus by a human antibody.
Sci Transl Med, 4, 2012
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1GNE
 | | THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | | 著者 | Lim, K, Ho, J.X, Keeling, K, Gilliland, G.L, Ji, X, Ruker, F, Carter, D.C. | | 登録日 | 1994-06-16 | | 公開日 | 1994-11-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV.
Protein Sci., 3, 1994
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4GQX
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4EJ0
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4K3J
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1JPS
 | | Crystal structure of tissue factor in complex with humanized Fab D3h44 | | 分子名称: | immunoglobulin Fab D3H44, heavy chain, light chain, ... | | 著者 | Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A. | | 登録日 | 2001-08-03 | | 公開日 | 2002-02-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
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1JPT
 | | Crystal Structure of Fab D3H44 | | 分子名称: | immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ... | | 著者 | Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A. | | 登録日 | 2001-08-03 | | 公開日 | 2002-02-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
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4DVH
 | | Crystal structure of Trypanosoma cruzi mitochondrial iron superoxide dismutase | | 分子名称: | FE (III) ION, Superoxide dismutase | | 著者 | Larrieux, N, Buschiazzo, A. | | 登録日 | 2012-02-23 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B: DISPARATE SUSCEPTIBILITIES DUE TO THE REPAIR OF TYR35 RADICAL BY CYS83 IN Fe-SODB THROUGH INTRAMOLECULAR ELECTRON TRANSFER.
J.Biol.Chem., 289, 2014
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5CFE
 | | Bacillus subtilis AP endonuclease ExoA | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Exodeoxyribonuclease | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2015-07-08 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.
Biochimie, 128-129, 2016
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5CFG
 | | C2 crystal form of APE1 with Mg2+ | | 分子名称: | DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2015-07-08 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural comparison of AP endonucleases from the exonuclease III family reveals new amino acid residues in human AP endonuclease 1 that are involved in incision of damaged DNA.
Biochimie, 128-129, 2016
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6P5G
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6P4I
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