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6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
著者Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
登録日2017-10-07
公開日2017-11-29
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
7RRW
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BU of 7rrw by Molmil
Monomeric CRM197 expressed in E. coli
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Diphtheria toxin
著者Gallagher, D.T, Lees, A.
登録日2021-08-10
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Monomeric crystal structure of the vaccine carrier protein CRM 197 and implications for vaccine development.
Acta Crystallogr.,Sect.F, 79, 2023
4JTD
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BU of 4jtd by Molmil
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
著者Banerjee, A, Lee, A, Campbell, E, MacKinnon, R.
登録日2013-03-23
公開日2013-06-12
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
4JTC
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BU of 4jtc by Molmil
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Banerjee, A, Lee, A, Campbell, E, MacKinnon, R.
登録日2013-03-23
公開日2013-06-12
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
4JTA
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BU of 4jta by Molmil
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
著者MacKinnon, R, Banerjee, A, Lee, A, Campbell, E.
登録日2013-03-23
公開日2013-06-12
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
1BE9
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BU of 1be9 by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
分子名称: CRIPT, PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1BYW
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BU of 1byw by Molmil
STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN-ERG POTASSIUM CHANNEL
分子名称: PROTEIN (HUMAN ERG POTASSIUM CHANNEL)
著者Cabral, J.H.M, Lee, A, Mackinnon, R.
登録日1998-10-15
公開日1998-12-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure and Functional Analysis of the Herg Potassium Channel N-Terminus: A Eukaryotic Pas Domain
Cell(Cambridge,Mass.), 95, 1998
6NJX
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BU of 6njx by Molmil
C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with mercury
分子名称: IODIDE ION, MERCURY (II) ION, Xcc_ctr_Hg
著者Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S.
登録日2019-01-04
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
6NK8
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BU of 6nk8 by Molmil
C-terminal region of the Burkholderia pseudomallei OLD protein
分子名称: Class 2 OLD family nuclease, MAGNESIUM ION
著者Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S.
登録日2019-01-05
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
6NJV
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BU of 6njv by Molmil
C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with iodine
分子名称: IODIDE ION, MAGNESIUM ION, Xcc_CTR_I
著者Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S.
登録日2019-01-04
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
6NJW
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BU of 6njw by Molmil
C-terminal region of the Xanthomonas campestris pv. campestris OLD protein phased with platinum
分子名称: IODIDE ION, MAGNESIUM ION, PLATINUM (II) ION, ...
著者Schiltz, C.J, Lee, A, Partlow, E.A, Hosford, C.J, Chappie, J.S.
登録日2019-01-04
公開日2019-08-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage.
Nucleic Acids Res., 47, 2019
1BFE
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BU of 1bfe by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
分子名称: PSD-95
著者Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日1998-05-20
公開日1998-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1LNQ
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BU of 1lnq by Molmil
CRYSTAL STRUCTURE OF MTHK AT 3.3 A
分子名称: CALCIUM ION, POTASSIUM CHANNEL RELATED PROTEIN
著者Jiang, Y, Lee, A, Chen, J, Cadene, M, Chait, B.T, Mackinnon, R.
登録日2002-05-03
公開日2002-06-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献CRYSTAL STRUCTURE AND MECHANISM OF A CALCIUM-GATED POTASSIUM CHANNEL
Nature, 417, 2002
2A0L
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BU of 2a0l by Molmil
Crystal structure of KvAP-33H1 Fv complex
分子名称: 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel
著者Lee, S.Y, Lee, A, Chen, J, Mackinnon, R.
登録日2005-06-16
公開日2005-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3PSH
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BU of 3psh by Molmil
Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to Molybdate)
分子名称: MOLYBDATE ION, protein HI_1472
著者Tirado-Lee, L, Lee, A, Rees, D.C, Pinkett, H.W.
登録日2010-12-01
公開日2011-11-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA.
Structure, 19, 2011
1ORS
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BU of 1ors by Molmil
X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab
分子名称: 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel
著者Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
登録日2003-03-14
公開日2003-05-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
1ORQ
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BU of 1orq by Molmil
X-ray structure of a voltage-dependent potassium channel in complex with an Fab
分子名称: 6E1 Fab heavy chain, 6E1 Fab light chain, CADMIUM ION, ...
著者Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
登録日2003-03-14
公開日2003-05-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-ray structure of a voltage-dependent K+ channel
Nature, 423, 2003
3PSA
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BU of 3psa by Molmil
Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to tungstate)
分子名称: TUNGSTATE(VI)ION, protein HI_1472
著者Tirado-Lee, L, Lee, A, Rees, D.C, Pinkett, H.W.
登録日2010-12-01
公開日2011-11-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA.
Structure, 19, 2011
3LNM
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BU of 3lnm by Molmil
F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Tao, X, Lee, A, Limapichat, W, Dougherty, D.A, MacKinnon, R.
登録日2010-02-02
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A gating charge transfer center in voltage sensors.
Science, 328, 2010
2RVC
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BU of 2rvc by Molmil
Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase
分子名称: Interferon-inducible and double-stranded-dependent eIF-2kinase
著者Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J.
登録日2015-07-08
公開日2016-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition.
Nucleic Acids Res., 44, 2016
5D8J
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BU of 5d8j by Molmil
Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
分子名称: Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
著者Doyle, C, Birrane, G.
登録日2015-08-17
公開日2016-01-13
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Sci Transl Med, 7, 2015
2G6F
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BU of 2g6f by Molmil
Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
分子名称: COBALT HEXAMMINE(III), Rho guanine nucleotide exchange factor 7
著者Hoelz, A.
登録日2006-02-24
公開日2006-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献Crystal Structure of the SH3 Domain of betaPIX in Complex with a High Affinity Peptide from PAK2
J.Mol.Biol., 358, 2006
8EF3
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BU of 8ef3 by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D
分子名称: rhMZ119-D antibody heavy chain, rhMZ119-D antibody light chain
著者Sankhala, R.S, Joyce, M.G.
登録日2022-09-07
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.672 Å)
主引用文献Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EE8
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BU of 8ee8 by Molmil
Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E glycoprotein
分子名称: Envelope protein E, rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain
著者Sankhala, R.S, Joyce, M.G.
登録日2022-09-06
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023
8EE5
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Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, rhMZ119-D antibody heavy chain, ...
著者Sankhala, R.S, Joyce, M.G.
登録日2022-09-06
公開日2023-08-30
実験手法X-RAY DIFFRACTION (3.583 Å)
主引用文献Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes.
Cell Rep, 42, 2023

 

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