2F76
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![BU of 2f76 by Molmil](/molmil-images/mine/2f76) | Solution structure of the M-PMV wild type matrix protein (p10) | 分子名称: | Core protein p10 | 著者 | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | 登録日 | 2005-11-30 | 公開日 | 2006-12-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
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2F77
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![BU of 2f77 by Molmil](/molmil-images/mine/2f77) | Solution structure of the R55F mutant of M-PMV matrix protein (p10) | 分子名称: | Core protein p10 | 著者 | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | 登録日 | 2005-11-30 | 公開日 | 2006-12-05 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
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6CCJ
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6CE5
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6CUS
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6CW4
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![BU of 6cw4 by Molmil](/molmil-images/mine/6cw4) | HADDOCK structure of the Rous sarcoma virus matrix protein (M-domain) in complex with inositol 1,3,5-trisphosphate | 分子名称: | (1R,2S,3r,4R,5S,6s)-2,4,6-trihydroxycyclohexane-1,3,5-triyl tris[dihydrogen (phosphate)], Matrix protein p19 | 著者 | Vlach, J, Saad, J.S. | 登録日 | 2018-03-29 | 公開日 | 2018-10-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly. J. Biol. Chem., 293, 2018
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6CV8
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![BU of 6cv8 by Molmil](/molmil-images/mine/6cv8) | HADDOCK structure of the Rous sarcoma virus matrix protein (M-domain) in complex with inositol 1,4,5-trisphosphate | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Matrix protein p19 | 著者 | Vlach, J, Saad, J.S. | 登録日 | 2018-03-27 | 公開日 | 2018-10-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly. J. Biol. Chem., 293, 2018
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2LYA
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2LYB
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![BU of 2lyb by Molmil](/molmil-images/mine/2lyb) | |
2MGU
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4NCV
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![BU of 4ncv by Molmil](/molmil-images/mine/4ncv) | Foldon domain wild type N-conjugate | 分子名称: | Fibritin | 著者 | Graewert, M.A, Berthelmann, A, Lach, J, Groll, M, Eichler, J. | 登録日 | 2013-10-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer. Org.Biomol.Chem., 12, 2014
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4NCW
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![BU of 4ncw by Molmil](/molmil-images/mine/4ncw) | foldon domain wild type C-conjugate | 分子名称: | Fibritin, N,N',N''-triethylbenzene-1,3,5-tricarboxamide | 著者 | Graewert, M.A, Berthelmann, A, Lach, J, Groll, M, Eichler, J. | 登録日 | 2013-10-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer. Org.Biomol.Chem., 12, 2014
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2XNB
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![BU of 2xnb by Molmil](/molmil-images/mine/2xnb) | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | 分子名称: | 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | 登録日 | 2010-08-01 | 公開日 | 2010-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents Chem.Biol., 17, 2010
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2XMY
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![BU of 2xmy by Molmil](/molmil-images/mine/2xmy) | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | 分子名称: | 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | 登録日 | 2010-07-29 | 公開日 | 2010-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents Chem.Biol., 17, 2010
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5VWL
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3TTI
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![BU of 3tti by Molmil](/molmil-images/mine/3tti) | Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor | 分子名称: | GLYCEROL, Mitogen-activated protein kinase 10, trans-4-({9-[(3S)-tetrahydrofuran-3-yl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl}amino)cyclohexanol | 著者 | Plantevin-Krenitsky, V, Nadolny, L, Delgado, M, Ayala, L, Clareen, S, Hilgraf, R, Albers, R, Hegde, S, D'Sidocky, N, Sapienza, J, Wright, J, McCarrick, M, Bahmanyar, S, Chamberlain, P, Delker, S.L, Muir, J, Giegel, D, Xu, L, Celeridad, M, Lachowitzer, J, Bennett, B, Moghaddam, M, Khatsenko, O, Katz, J, Fan, R, Bai, A, Tang, Y, Shirley, M.A, Benish, B, Bodine, T, Blease, K, Raymon, H, Cathers, B.E, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
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8DKU
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![BU of 8dku by Molmil](/molmil-images/mine/8dku) | CryoEM structure of the A. aeolicus WzmWzt transporter bound to the native O antigen | 分子名称: | 6-deoxy-3-O-methyl-alpha-D-mannopyranose-(1-3)-beta-D-rhamnopyranose-(1-2)-alpha-D-rhamnopyranose, ABC transporter, Transport permease protein | 著者 | Spellmon, N, Muszynski, A, Vlach, J, Zimmer, J. | 登録日 | 2022-07-06 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter. Nat Commun, 13, 2022
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8DNC
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![BU of 8dnc by Molmil](/molmil-images/mine/8dnc) | CryoEM structure of the A. aeolicus WzmWzt transporter bound to the native O antigen and ADP | 分子名称: | 6-deoxy-3-O-methyl-alpha-D-mannopyranose-(1-3)-beta-D-rhamnopyranose-(1-2)-alpha-D-rhamnopyranose, ABC transporter, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Spellmon, N, Muszynski, A, Vlach, J, Zimmer, J. | 登録日 | 2022-07-11 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter. Nat Commun, 13, 2022
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2N9C
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![BU of 2n9c by Molmil](/molmil-images/mine/2n9c) | NRAS Isoform 5 | 分子名称: | GTPase NRas | 著者 | Markowitz, J, Mal, T.K, Yuan, C, Courtney, N.B, Patel, M, Stiff, A.R, Blachly, J, Walker, C, Eisfeld, A, de la Chapelle, A, Carson III, W.E. | 登録日 | 2015-11-13 | 公開日 | 2016-03-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of NRAS isoform 5. Protein Sci., 25, 2016
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1M8W
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![BU of 1m8w by Molmil](/molmil-images/mine/1m8w) | CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA | 分子名称: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*CP*CP*AP*G)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', ... | 著者 | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | 登録日 | 2002-07-26 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8Y
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![BU of 1m8y by Molmil](/molmil-images/mine/1m8y) | CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE2-10 RNA | 分子名称: | 5'-R(P*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3', Pumilio 1 | 著者 | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | 登録日 | 2002-07-26 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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1M8X
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![BU of 1m8x by Molmil](/molmil-images/mine/1m8x) | CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA | 分子名称: | 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', Pumilio 1 | 著者 | Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. | 登録日 | 2002-07-26 | 公開日 | 2002-09-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
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4RLE
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![BU of 4rle by Molmil](/molmil-images/mine/4rle) | Crystal structure of the c-di-AMP binding PII-like protein DarA | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, NICKEL (II) ION, Uncharacterized protein YaaQ | 著者 | Dickmanns, A, Neumann, P, Ficner, R. | 登録日 | 2014-10-16 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA. J.Biol.Chem., 290, 2015
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6ZJZ
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![BU of 6zjz by Molmil](/molmil-images/mine/6zjz) | Discovery of M5049: a novel selective TLR7/8 inhibitor for treatment of autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile, FORMIC ACID, ... | 著者 | Musil, D, Lehman, M, Strauss, J. | 登録日 | 2020-06-29 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity. J.Pharmacol.Exp.Ther., 376, 2021
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4NCU
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