3KXC
 
 | | Mutant transport protein | | 分子名称: | PALMITIC ACID, Trafficking protein particle complex subunit 3, Trafficking protein particle complex subunit 6B | | 著者 | Kummel, D, Heinemann, U. | | 登録日 | 2009-12-02 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of the self-palmitoylation activity of the transport protein particle component Bet3
Cell.Mol.Life Sci., 67, 2010
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2BJN
 | | X-ray Structure of human TPC6 | | 分子名称: | GLYCEROL, SULFATE ION, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B | | 著者 | Kummel, D, Mueller, J.J, Roske, Y, Misselwitz, R, Bussow, K, Heinemann, U. | | 登録日 | 2005-02-04 | | 公開日 | 2005-07-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Structure of the Trapp Subunit Tpc6 Suggests a Model for a Trapp Subcomplex.
Embo Rep., 6, 2005
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2CFH
 | | Structure of the Bet3-TPC6B core of TRAPP | | 分子名称: | PALMITIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B | | 著者 | Kummel, D, Muller, J.J, Roske, Y, Henke, N, Heinemann, U. | | 登録日 | 2006-02-21 | | 公開日 | 2006-07-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Bet3-Tpc6B Core of Trapp: Two Tpc6 Paralogs Form Trimeric Complexes with Bet3 and Mum2.
J.Mol.Biol., 361, 2006
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5HIU
 | | Structure of the TSC2 N-terminus | | 分子名称: | GTPase activator-like protein | | 著者 | Zech, R, Kiontke, S, Kummel, D. | | 登録日 | 2016-01-12 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
J.Biol.Chem., 291, 2016
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8CPN
 | | Crystal structure of the PolB16_OarG intein variant S1A, N183A | | 分子名称: | IODIDE ION, PolB16 intein | | 著者 | Kattelmann, S, Pasch, T, Mootz, H.D, Kummel, D. | | 登録日 | 2023-03-03 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins.
Chem Sci, 14, 2023
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2W3C
 | | Globular head region of the human general vesicular transport factor p115 | | 分子名称: | DI(HYDROXYETHYL)ETHER, GENERAL VESICULAR TRANSPORT FACTOR P115 | | 著者 | Striegl, H, Roske, Y, Kummel, D, Heinemann, U. | | 登録日 | 2008-11-11 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Unusual Armadillo Fold in the Human General Vesicular Transport Factor P115
Plos One, 4, 2009
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6SSH
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3TW8
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6ZFM
 | | Structure of alpha-Cobratoxin with a peptide inhibitor | | 分子名称: | 3-[2-[2-[2-[2-[2-(2-azanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propan-1-ol, Alpha-cobratoxin, PENTAETHYLENE GLYCOL, ... | | 著者 | Kiontke, S, Kummel, D. | | 登録日 | 2020-06-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Peptide Inhibitors of the alpha-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction.
J.Med.Chem., 63, 2020
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7FSE
 | | Crystal Structure of T. maritima reverse gyrase with a minimal latch | | 分子名称: | CHLORIDE ION, DODECAETHYLENE GLYCOL, Reverse gyrase, ... | | 著者 | Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. | | 登録日 | 2023-01-04 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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7FSF
 | | CRYSTAL STRUCTURE OF T. MARITIMA REVERSE GYRASE ACTIVE SITE VARIANT Y851F | | 分子名称: | Reverse gyrase, ZINC ION | | 著者 | Rasche, R, Kummel, D, Rudolph, M.G, Klostermeier, D. | | 登録日 | 2023-01-04 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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1TBX
 | | Crystal structure of SSV1 F-93 | | 分子名称: | Hypothetical 11.0 kDa protein | | 著者 | Kraft, P, Oeckinghaus, A, Kummel, D, Gauss, G.H, Wiedenheft, B, Young, M, Lawrence, C.M. | | 登録日 | 2004-05-20 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of F-93 from Sulfolobus spindle-shaped virus 1, a winged-helix DNA binding protein.
J.Virol., 78, 2004
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8OFB
 | | Crystal Structure of T. maritima reverse gyrase with a minimal latch, hexagonal form | | 分子名称: | CHLORIDE ION, HEXAETHYLENE GLYCOL, Reverse gyrase, ... | | 著者 | Klostermeier, D, Rasche, R, Mhaindarkar, V, Kummel, D, Rudolph, M.G. | | 登録日 | 2023-03-15 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structure of reverse gyrase with a minimal latch that supports ATP-dependent positive supercoiling without specific interactions with the topoisomerase domain.
Acta Crystallogr D Struct Biol, 79, 2023
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3RL0
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3RK3
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3RK2
 | | Truncated SNARE complex | | 分子名称: | CALCIUM ION, Synaptosomal-associated protein 25, Syntaxin-1A, ... | | 著者 | Kuemmel, D, Reinisch, K.M. | | 登録日 | 2011-04-17 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Complexin cross-links prefusion SNAREs into a zigzag array.
Nat.Struct.Mol.Biol., 18, 2011
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7A0N
 | | Structure of TSC1 NTD and linker domain | | 分子名称: | Uncharacterized protein,Uncharacterized protein | | 著者 | Fitzian, K, Kuemmel, D. | | 登録日 | 2020-08-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Mol.Cell, 81, 2021
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7A0M
 | | TSC1 N-terminal domain | | 分子名称: | SULFATE ION, TSC1 N-terminal domain | | 著者 | Zech, R, Kiontke, S, Kuemmel, D. | | 登録日 | 2020-08-10 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Mol.Cell, 81, 2021
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7ZTY
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8C7G
 | | Drosophila melanogaster Rab7 GEF complex Mon1-Ccz1-Bulli | | 分子名称: | Caffeine, calcium, zinc sensitivity 1, ... | | 著者 | Schaefer, J, Herrmann, E, Kuemmel, D, Moeller, A. | | 登録日 | 2023-01-15 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the metazoan Rab7 GEF complex Mon1-Ccz1-Bulli.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8CPO
 | | Crystal structure of the PolB16_OarG intein variant S1A, N183A, C111A, C165A | | 分子名称: | PolB16 Intein Cys-less | | 著者 | Kattelmann, S, Pasch, T, Mootz, H.D, Kuemmel, D. | | 登録日 | 2023-03-03 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and biochemical analysis of a novel atypically split intein reveals a conserved histidine specific to cysteine-less inteins.
Chem Sci, 14, 2023
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8CCI
 | | Crystal structure of Mycobacterium smegmatis thioredoxin reductase | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Fuesser, F.T, Koch, O, Kuemmel, D. | | 登録日 | 2023-01-27 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Novel starting points for fragment-based drug design against mycobacterial thioredoxin reductase identified using crystallographic fragment screening.
Acta Crystallogr D Struct Biol, 79, 2023
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5LDD
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7ZU0
 | | HOPS tethering complex from yeast | | 分子名称: | E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar morphogenesis protein 6, ... | | 著者 | Shvarev, D, Schoppe, J, Koenig, C, Perz, A, Fuellbrunn, N, Kiontke, S, Langemeyer, L, Januliene, D, Schnelle, K, Kuemmel, D, Froehlich, F, Moeller, A, Ungermann, C. | | 登録日 | 2022-05-11 | | 公開日 | 2022-09-28 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery.
Elife, 11, 2022
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4UUY
 | | Structural Identification of the Vps18 beta-propeller reveals a critical role in the HOPS complex stability and function. | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... | | 著者 | Behrmann, H, Gohlke, U, Heinemann, U. | | 登録日 | 2014-08-01 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural Identification of the Vps18 Beta-Propeller Reveals a Critical Role in the Hops Complex Stability and Function.
J.Biol.Chem., 289, 2014
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