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4X6R
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BU of 4x6r by Molmil
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Wu, J, Taylor, S.S.
登録日2014-12-09
公開日2015-07-22
最終更新日2020-06-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
4X6Q
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BU of 4x6q by Molmil
An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Ye, F, Bastidas, A.C, Kornev, A.P, Ginsberg, M.H, Taylor, S.S.
登録日2014-12-08
公開日2015-07-22
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
Structure, 23, 2015
4DIN
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BU of 4din by Molmil
Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Ilouz, R, Bubis, J, Wu, J, Yim, Y.Y, Deal, M.S, Kornev, A.P, Ma, Y, Blumenthal, D.K, Taylor, S.S.
登録日2012-01-31
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Localization and quaternary structure of the PKA RI Beta holoenzyme
Proc.Natl.Acad.Sci.USA, 109, 2012
4MX3
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BU of 4mx3 by Molmil
Crystal Structure of PKA RIalpha Homodimer
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Bruystens, J.G.H, Wu, J, Fortezzo, A, Kornev, A.P, Blumenthal, D.A, Taylor, S.S.
登録日2013-09-25
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.88 Å)
主引用文献PKA RI alpha Homodimer Structure Reveals an Intermolecular Interface with Implications for Cooperative cAMP Binding and Carney Complex Disease.
Structure, 22, 2014
3TNQ
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BU of 3tnq by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3TNP
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BU of 3tnp by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3PVB
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BU of 3pvb by Molmil
Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S.
登録日2010-12-06
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Structure, 19, 2011
3FJQ
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BU of 3fjq by Molmil
Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide inhibitor PKI alpha (6-25)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Kim, C.
登録日2008-12-15
公開日2009-08-04
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Comparative surface geometry of the protein kinase family.
Protein Sci., 18, 2009
3QAM
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BU of 3qam by Molmil
Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3QAL
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BU of 3qal by Molmil
Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ...
著者Yang, J, Wu, J, Steichen, J, Taylor, S.S.
登録日2011-01-11
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
J.Mol.Biol., 415, 2012
3SHR
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BU of 3shr by Molmil
Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cGMP-dependent protein kinase 1
著者Osborne, B.W, Wu, J, Taylor, S.S, Dostmann, W.R.
登録日2011-06-16
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication.
Structure, 19, 2011
3IIA
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BU of 3iia by Molmil
Crystal structure of apo (91-244) RIa subunit of cAMP-dependent protein kinase
分子名称: GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Sjoberg, T.J, Kim, C, Kornev, A.P, Taylor, S.S.
登録日2009-07-31
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Mol.Cell Proteomics, 10, 2011

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