1ULZ
 
 | | Crystal structure of the biotin carboxylase subunit of pyruvate carboxylase | | 分子名称: | pyruvate carboxylase n-terminal domain | | 著者 | Kondo, S, Nakajima, Y, Sugio, S, Yong-Biao, J, Sueda, S, Kondo, H. | | 登録日 | 2003-09-18 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
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2DZD
 | | Crystal structure of the biotin carboxylase domain of pyruvate carboxylase | | 分子名称: | pyruvate carboxylase | | 著者 | Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H. | | 登録日 | 2006-09-27 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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1G1Y
 | | CRYSTAL STRUCTURE OF ALPHA-AMYLASE II (TVAII) FROM THERMOACTINOMYCES VULGARIS R-47 AND BETA-CYCLODEXTRIN COMPLEX | | 分子名称: | ALPHA-AMYLASE II, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | | 著者 | Kondo, S, Ohtaki, A, Tonozuka, T, Sakano, Y, Kamitori, S. | | 登録日 | 2000-10-16 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Studies on the hydrolyzing mechanism for cyclodextrins of Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structure of the mutant E354A complexed with beta-cyclodextrin, and kinetic analyses on cyclodextrins.
J.Biochem.(Tokyo), 129, 2001
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4W96
 | | Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 followed by the reaction in deoxy-myoglobin solution | | 分子名称: | CHLORIDE ION, DIMETHYLFORMAMIDE, Lysozyme C, ... | | 著者 | Tabe, H, Fujita, K, Abe, S, Tsujimoto, M, Kuchimaru, T, Kizaka-Kondo, S, Takano, M, Kitagawa, S, Ueno, T. | | 登録日 | 2014-08-27 | | 公開日 | 2014-12-31 | | 最終更新日 | 2020-01-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold
Inorg.Chem., 54, 2015
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1N5X
 | | Xanthine Dehydrogenase from Bovine Milk with Inhibitor TEI-6720 Bound | | 分子名称: | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Okamoto, K, Eger, B.T, Nishino, T, Kondo, S, Pai, E.F, Nishino, T. | | 登録日 | 2002-11-07 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | An Extremely Potent Inhibitor of Xanthine Oxidoreductase: Crystal Structure of the Enzyme-Inhibitor Complex and Mechanism of Inhibition
J.BIOL.CHEM., 278, 2003
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8Z5L
 | | Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor | | 分子名称: | 3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic acid, Metallo-beta-lactamase type 2, ZINC ION | | 著者 | Kamo, T, Kuroda, K, Nimura, S, Guo, Y, Kondo, S, Nukaga, M, Hoshino, T. | | 登録日 | 2024-04-18 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis.
Biochemistry, 63, 2024
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4W94
 | | Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 | | 分子名称: | CHLORIDE ION, DIMETHYLFORMAMIDE, Lysozyme C, ... | | 著者 | Tabe, H, Fujita, K, Abe, S, Tsujimoto, M, Kuchimaru, T, Kizaka-Kondo, S, Takano, M, Kitagawa, S, Ueno, T. | | 登録日 | 2014-08-27 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold
Inorg.Chem., 54, 2015
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1BVZ
 | | ALPHA-AMYLASE II (TVAII) FROM THERMOACTINOMYCES VULGARIS R-47 | | 分子名称: | PROTEIN (ALPHA-AMYLASE II) | | 著者 | Kamitori, S, Kondo, S, Okuyama, K, Yokota, T, Shimura, Y, Tonozuka, T, Sakano, Y. | | 登録日 | 1998-09-22 | | 公開日 | 1999-03-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of Thermoactinomyces vulgaris R-47 alpha-amylase II (TVAII) hydrolyzing cyclodextrins and pullulan at 2.6 A resolution.
J.Mol.Biol., 287, 1999
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1JF6
 | | Crystal structure of thermoactinomyces vulgaris r-47 alpha-amylase mutant F286Y | | 分子名称: | ALPHA AMYLASE II, CALCIUM ION | | 著者 | Ohtaki, A, Kondo, S, Shimura, Y, Tonozuka, T, Sakano, Y, Kamitori, S. | | 登録日 | 2001-06-20 | | 公開日 | 2002-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Role of Phe286 in the recognition mechanism of cyclomaltooligosaccharides (cyclodextrins) by Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structures of the mutant TVAIIs, F286A and F286Y, and kinetic analyses of the Phe286-replaced mutant TVAIIs
CARBOHYDR.RES., 334, 2001
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1JF5
 | | CRYSTAL STRUCTURE OF THERMOACTINOMYCES VULGARIS R-47 ALPHA-AMYLASE 2 MUTANT F286A | | 分子名称: | ALPHA AMYLASE II, CALCIUM ION | | 著者 | Ohtaki, A, Kondo, S, Shimura, Y, Tonozuka, T, Sakano, Y, Kamitori, S. | | 登録日 | 2001-06-20 | | 公開日 | 2002-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Role of Phe286 in the recognition mechanism of cyclomaltooligosaccharides (cyclodextrins) by Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structures of the mutant TVAIIs, F286A and F286Y, and kinetic analyses of the Phe286-replaced mutant TVAIIs
CARBOHYDR.RES., 334, 2001
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3AWK
 | | Crystal structure of the polyketide synthase 1 from huperzia serrata | | 分子名称: | Chalcone synthase-like polyketide synthase, GLYCEROL, SULFATE ION | | 著者 | Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I. | | 登録日 | 2011-03-23 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3AWJ
 | | Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH | | 分子名称: | COENZYME A, Chalcone synthase-like polyketide synthase, SULFATE ION | | 著者 | Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I. | | 登録日 | 2011-03-23 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6JKA
 | | Crystal structure of metallo-beta-lactamse, IMP-1, in complex with a thiazole-bearing inhibitor | | 分子名称: | 3-[2-azanyl-5-[2-(phenoxymethyl)-1,3-thiazol-4-yl]phenyl]propanoic acid, 6-[2-(phenoxymethyl)-1,3-thiazol-4-yl]-3,4-dihydro-1H-quinolin-2-one, Metallo-beta-lactamase type 2, ... | | 著者 | Kamo, T, Kuroda, K, Kondo, S, Hayashi, U, Fudo, S, Nukaga, M, Hoshino, T. | | 登録日 | 2019-02-28 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Identification of the Inhibitory Compounds for Metallo-beta-lactamases and Structural Analysis of the Binding Modes.
Chem Pharm Bull (Tokyo), 69, 2021
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6JKB
 | | Crystal structure of metallo-beta-lactamse, NDM-1, in complex with hydrolyzed ampicillin | | 分子名称: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Metallo-beta-lactamase type 2, ZINC ION | | 著者 | Kamo, T, Kuroda, K, Kondo, S, Hayashi, U, Fudo, S, Nukaga, M, Hoshino, T. | | 登録日 | 2019-02-28 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.444 Å) | | 主引用文献 | Identification of the Inhibitory Compounds for Metallo-beta-lactamases and Structural Analysis of the Binding Modes.
Chem Pharm Bull (Tokyo), 69, 2021
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2D3M
 | | Pentaketide chromone synthase complexed with coenzyme A | | 分子名称: | COENZYME A, pentaketide chromone synthase | | 著者 | Morita, H, Kondo, S, Oguro, S, Noguchi, H, Sugio, S, Abe, I, Kohno, T. | | 登録日 | 2005-09-29 | | 公開日 | 2006-10-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens
Chem.Biol., 14, 2007
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2D39
 | | Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain | | 分子名称: | CALCIUM ION, Ficolin-1 | | 著者 | Tanio, M, Kondo, S, Sugio, S, Kohno, T. | | 登録日 | 2005-09-26 | | 公開日 | 2006-12-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Trivalent recognition unit of innate immunity system; crystal structure of trimeric human m-ficolin fibrinogen-like domain
J.Biol.Chem., 282, 2007
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3WVV
 | | Crystal Structure of RuCO/apo-E45C_C48AFr | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... | | 著者 | Fujita, K, Tanaka, Y, Abe, S, Hikage, T, Kuchimaru, T, Kizaka-Kondoh, S, Ueno, T. | | 登録日 | 2014-06-09 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Intracellular CO release from composite of ferritin and ruthenium carbonyl complexes.
J.Am.Chem.Soc., 136, 2014
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3WVU
 | | Crystal Structure of RuCO/apo-R52CFr | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... | | 著者 | Fujita, K, Tanaka, Y, Abe, S, Hikage, T, Kuchimaru, T, Kizaka-Kondoh, S, Ueno, T. | | 登録日 | 2014-06-09 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Intracellular CO release from composite of ferritin and ruthenium carbonyl complexes.
J.Am.Chem.Soc., 136, 2014
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3WVW
 | | Crystal structure of RuCO/apo-WTFr | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... | | 著者 | Fujita, K, Tanaka, Y, Abe, S, Hikage, T, Kuchimaru, T, Kizaka-Kondoh, S, Ueno, T. | | 登録日 | 2014-06-09 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Intracellular CO release from composite of ferritin and ruthenium carbonyl complexes.
J.Am.Chem.Soc., 136, 2014
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5AXI
 | | Crystal structure of Cbl-b TKB domain in complex with Cblin | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cblin, ... | | 著者 | Ohno, A, Maita, N, Ochi, A, Nakao, R, Nikawa, T. | | 登録日 | 2015-07-29 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis of the TKB domain of ubiquitin ligase Cbl-b complexed with its small inhibitory peptide, Cblin
Arch.Biochem.Biophys., 594, 2016
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8PBV
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7LS3
 | | Co-complex CYP46A1 with 8114 (3f) | | 分子名称: | (5-methyl-2-pyridin-4-yl-phenyl)-[4-oxidanyl-4-(phenylmethyl)piperidin-1-yl]methanone, Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lane, W, Yano, J. | | 登録日 | 2021-02-17 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H).
J.Med.Chem., 64, 2021
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7LRL
 | | Co-complex CYP46A1 with 7742 (Soticlestat/TAK-935)) | | 分子名称: | Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, [4-oxidanyl-4-(phenylmethyl)piperidin-1-yl]-(2-pyridin-4-ylpyridin-3-yl)methanone | | 著者 | Lane, W, Yano, J. | | 登録日 | 2021-02-16 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H).
J.Med.Chem., 64, 2021
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7LS4
 | | Co-complex CYP46A1 with 9129 (1b) | | 分子名称: | Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, [5,5-dimethyl-3-(2-methylphenyl)-4~{H}-pyrazol-1-yl]-pyridin-4-yl-methanone | | 著者 | Lane, W, Yano, J. | | 登録日 | 2021-02-17 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H).
J.Med.Chem., 64, 2021
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6KD5
 | | Crystal structure of the extracellular domain of MSPL/TMPRSS13 in complex with dec-RVKR-cmk inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | | 著者 | Ohno, A, Maita, N, Okumura, Y, Nikawa, T. | | 登録日 | 2019-06-30 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.
Life Sci Alliance, 4, 2021
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