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6IEZ
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BU of 6iez by Molmil
Crystal structure of CERT START domain in complex with compound B16
分子名称: 2-({4'-pentyl-3'-[2-(pyridin-2-yl)ethyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-09-18
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6IF0
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BU of 6if0 by Molmil
Crystal structure of CERT START domain in complex with compound D16
分子名称: 2-({4'-pentyl-3'-[(Z)-2-(pyridin-2-yl)ethenyl][1,1'-biphenyl]-4-yl}sulfonyl)ethan-1-ol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-09-18
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6J81
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BU of 6j81 by Molmil
Crystal structure of CERT START domain in complex with compound E14
分子名称: 2-[4-[4-propyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2019-01-18
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
6J0O
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BU of 6j0o by Molmil
Crystal structure of CERT START domain in complex with compound SC1
分子名称: 2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT, UNKNOWN ATOM OR ION
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-12-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
1NBK
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BU of 1nbk by Molmil
The structure of RNA aptamer for HIV Tat complexed with two argininamide molecules
分子名称: 2-AMINO-5-GUANIDINO-PENTANOIC ACID, RNA aptamer
著者Matsugami, A, Kobayashi, S, Ouhashi, K, Uesugi, S, Yamamoto, R, Taira, K, Nishikawa, S, Kumar, P.K.R, Katahira, M.
登録日2002-12-03
公開日2003-12-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Basis of the Highly Efficient Trapping of the HIV Tat Protein by an RNA Aptamer
Structure, 11, 2003
5ZYL
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BU of 5zyl by Molmil
Crystal structure of CERT START domain in complex with compound E25A
分子名称: 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYI
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BU of 5zyi by Molmil
Crystal structure of CERT START domain in complex with compound E16
分子名称: 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYJ
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BU of 5zyj by Molmil
Crystal structure of CERT START domain in complex with compound E16A
分子名称: 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYH
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BU of 5zyh by Molmil
Crystal structure of CERT START domain in complex with compound E5
分子名称: 2-[4-[3-~{tert}-butyl-5-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYK
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BU of 5zyk by Molmil
Crystal structure of CERT START domain in complex with compound E25
分子名称: 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYG
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BU of 5zyg by Molmil
Crystal structure of CERT START domain in complex with compound B5
分子名称: 2-[4-[3-~{tert}-butyl-5-(2-pyridin-2-ylethyl)phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
5ZYM
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BU of 5zym by Molmil
Crystal structure of CERT START domain in complex with compound E25B
分子名称: 2-[4-[4-cyclopentyl-3-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT
著者Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K.
登録日2018-05-25
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
8WM0
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BU of 8wm0 by Molmil
Crystal structure of TNIK-thiopeptide wTP3 complex
分子名称: ADENOSINE, THIOPEPTIDE wTP3, TRAF2 and NCK-interacting protein kinase
著者Hamada, K, Kobayashi, S, Vinogradov, A.A, Zhang, Y, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2023-10-01
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Compact Reprogrammed Genetic Code for De Novo Discovery of Proteolytically Stable Thiopeptides.
J.Am.Chem.Soc., 2024
3ABD
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BU of 3abd by Molmil
Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M.
登録日2009-12-07
公開日2010-02-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1
J.Biol.Chem., 285, 2010
3ABE
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BU of 3abe by Molmil
Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal
分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
著者Hara, K, Hashimoto, H, Murakumo, Y, Kobayashi, S, Kogame, T, Unzai, S, Akashi, S, Takeda, S, Shimizu, T, Sato, M.
登録日2009-12-07
公開日2010-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase {zeta} and REV1
J.Biol.Chem., 285, 2010
7VMY
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BU of 7vmy by Molmil
Crystal structure of LimF prenyltransferase bound with GSPP
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, ...
著者Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2021-10-09
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
7VMW
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BU of 7vmw by Molmil
Crystal structure of LimF prenyltransferase bound with a peptide substrate and GSPP
分子名称: GERANYL S-THIOLODIPHOSPHATE, LynF/TruF/PatF family peptide O-prenyltransferase, MAGNESIUM ION, ...
著者Hamada, K, Kobayashi, S, Okada, C, Zhang, Y, Inoue, S, Goto, Y, Suga, H, Ogata, K, Sengoku, T.
登録日2021-10-09
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Nat Catal, 2022
2DB3
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BU of 2db3 by Molmil
Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
分子名称: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-dependent RNA helicase vasa, MAGNESIUM ION, ...
著者Sengoku, T, Nureki, O, Nakamura, A, Kobayashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2006-05-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa.
Cell(Cambridge,Mass.), 125, 2006
8GUJ
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BU of 8guj by Molmil
Bre1-nucleosome complex (Model II)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
8GUK
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BU of 8guk by Molmil
Human nucleosome core particle (free form)
分子名称: DNA (147-mer), Histone H2A type 1, Histone H2B type 1-J, ...
著者Onishi, S, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
8GUI
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BU of 8gui by Molmil
Bre1-nucleosome complex (Model I)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
3H3T
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BU of 3h3t by Molmil
Crystal structure of the CERT START domain in complex with HPA-16
分子名称: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]hexadecanamide
著者Kudo, N, Wakatsuki, S, Kato, R.
登録日2009-04-17
公開日2010-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
J.Mol.Biol., 396, 2010
3H3R
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BU of 3h3r by Molmil
Crystal structure of the CERT START domain in complex with HPA-14
分子名称: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tetradecanamide
著者Kudo, N, Wakatsuki, S, Kato, R.
登録日2009-04-17
公開日2010-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
J.Mol.Biol., 396, 2010
3H3S
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BU of 3h3s by Molmil
Crystal structure of the CERT START domain in complex with HPA-15
分子名称: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]pentadecanamide
著者Kudo, N, Wakatsuki, S, Kato, R.
登録日2009-04-17
公開日2010-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
J.Mol.Biol., 396, 2010
3H3Q
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Crystal structure of the CERT START domain in complex with HPA-13
分子名称: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]tridecanamide
著者Kudo, N, Wakatsuki, S, Kato, R.
登録日2009-04-17
公開日2010-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
J.Mol.Biol., 396, 2010

 

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