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1EV0
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BU of 1ev0 by Molmil
SOLUTION STRUCTURE OF THE MINE TOPOLOGICAL SPECIFICITY DOMAIN
分子名称: MINE
著者King, G.F, Maciejewski, M.W, Pan, B, Mullen, G.P.
登録日2000-04-19
公開日2000-11-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for the topological specificity function of MinE.
Nat.Struct.Biol., 7, 2000
2M6J
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BU of 2m6j by Molmil
Structure of a vertebrate toxin from the badge huntsman spider
分子名称: Toxin AbTx
著者King, G.F, Mobli, M, Brust, A, Fry, B.G.
登録日2013-04-04
公開日2014-04-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of a novel vertebrate toxin from the badge huntsman spider
To be Published
2KNI
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BU of 2kni by Molmil
High-resolution solution structure of the ASIC1a blocker PcTX1
分子名称: Psalmotoxin-1
著者King, G.F, Mobli, M, Saez, N.J.
登録日2009-08-25
公開日2010-09-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a.
Mol.Pharmacol., 80, 2011
2M35
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BU of 2m35 by Molmil
NMR study of k-Ssm1a
分子名称: k-Ssm1a
著者King, G.F, Undheim, E.A, Mobli, M, Yang, S, Rong, M, Lai, R.
登録日2013-01-09
公開日2014-01-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR study of k-Ssm1a
To be Published
2M36
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BU of 2m36 by Molmil
Solution structure of the insecticidal spider-venom peptide Aps III
分子名称: U2-cyrtautoxin-As1a
著者King, G.F, Bende, N.S, Mobli, M.
登録日2013-01-10
公開日2013-03-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels.
Biochem Pharmacol, 85, 2013
1U3O
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BU of 1u3o by Molmil
Solution structure of rat Kalirin N-terminal SH3 domain
分子名称: Huntingtin-associated protein-interacting protein
著者Schiller, M.R, Chakrabarti, K, King, G.F, Schiller, N.I, Eipper, B.A, Maciejewski, M.W.
登録日2004-07-22
公開日2005-07-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Regulation of RhoGEF Activity by Intramolecular and Intermolecular SH3 Domain Interactions.
J.Biol.Chem., 281, 2006
4MN5
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BU of 4mn5 by Molmil
Crystal structure of PAS domain of S. aureus YycG
分子名称: Sensor protein kinase WalK, ZINC ION
著者Shaikh, N, Hvorup, R, Winnen, B, Collins, B.M, King, G.F.
登録日2013-09-10
公開日2014-09-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of PAS domain of S. aureus YycG
To be Published
4MN6
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BU of 4mn6 by Molmil
Crystal structure of truncated PAS domain from S. aureus YycG
分子名称: Sensor protein kinase WalK, ZINC ION
著者Shaikh, N, Hvorup, R, Winnen, B, Collins, B.M, King, G.F.
登録日2013-09-10
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of PAS domain of S. aureus YycG
To be Published
5WLX
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BU of 5wlx by Molmil
Solution structure of kappa-theraphotoxin-Aa1a
分子名称: Kappa-theraphotoxin-Aa1a
著者Chin, Y.K.Y, Ma, L, King, G.F.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
1VTX
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BU of 1vtx by Molmil
DELTA-ATRACOTOXIN-HV1 (VERSUTOXIN) FROM HADRONYCHE VERSUTA, NMR, 20 STRUCTURES
分子名称: DELTA-ATRACOTOXIN-HV1
著者Fletcher, J.I, Chapman, B.E, King, G.F.
登録日1997-03-13
公開日1998-01-28
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel.
Structure, 5, 1997
2H1Z
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BU of 2h1z by Molmil
Structure of a dual-target spider toxin
分子名称: Hybrid atracotoxin
著者Sollod, B.L, Maciejewski, M.W, KIng, G.F.
登録日2006-05-17
公開日2007-05-22
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献A dual-target, self-synergizing toxin from spider venom
To be Published
8UNG
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BU of 8ung by Molmil
Solution structure of toxin, U-RDTX-Pp19, from assassin bug Pristhesancus plagipennis
分子名称: Venom peptide Pp19a
著者Chin, Y.K.Y, Walker, A.A, King, G.F.
登録日2023-10-18
公開日2024-05-29
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献Structure and bioactivity of an insecticidal trans-defensin from assassin bug venom.
Structure, 2024
6MZT
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BU of 6mzt by Molmil
Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi
分子名称: Potassium channel toxin alpha-KTx 6.21
著者Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F.
登録日2018-11-05
公開日2020-03-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem. Pharmacol., 174, 2020
6BA3
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BU of 6ba3 by Molmil
NMR structure of U21-hexatoxin-Hi1a toxin from Australian Funnel-web spider Hadronyche infensa
分子名称: U21-hexatoxin-Hi1a
著者Chin, Y.K.-Y, Pineda, S.S, King, G.F.
登録日2017-10-12
公開日2018-10-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
6AZA
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BU of 6aza by Molmil
NMR structure of sea anemone toxin Kappa-actitoxin-Ate1a
分子名称: ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
著者Chin, Y.K.-Y, Madio, B, King, G.F, Undheim, E.A.B.
登録日2017-09-10
公開日2018-09-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018
1JUN
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BU of 1jun by Molmil
NMR STUDY OF C-JUN HOMODIMER
分子名称: C-JUN HOMODIMER
著者Junius, F.K, O'Donoghue, S.I, Nilges, M, King, G.F.
登録日1995-12-19
公開日1996-06-20
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献High resolution NMR solution structure of the leucine zipper domain of the c-Jun homodimer.
J.Biol.Chem., 271, 1996
6A90
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BU of 6a90 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and Dc1a
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mu-diguetoxin-Dc1a, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A91
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BU of 6a91 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A95
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BU of 6a95 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a
分子名称: (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6V6T
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BU of 6v6t by Molmil
Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
分子名称: Delta-theraphotoxin-Hm1b
著者Chin, Y.K.Y, Chow, C.Y, King, G.F.
登録日2019-12-05
公開日2020-05-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
1HVW
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BU of 1hvw by Molmil
HAIRPINLESS MUTANT OF OMEGA-ATRACOTOXIN-HV1A
分子名称: OMEGA-ATRACOTOXIN-HV1A
著者Fletcher, J.I, King, G.F.
登録日2001-01-08
公開日2001-01-17
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a.
J.Biol.Chem., 276, 2001
1DL0
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BU of 1dl0 by Molmil
SOLUTION STRUCTURE OF THE INSECTICIDAL NEUROTOXIN J-ATRACOTOXIN-HV1C
分子名称: J-ATRACOTOXIN-HV1C
著者Wang, X.H, King, G.F.
登録日1999-12-08
公開日2000-09-15
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge.
Nat.Struct.Biol., 7, 2000
1HP3
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C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)
分子名称: OMEGA-ATRACOTOXIN-HV2A
著者Wang, X.-H, King, G.F.
登録日2000-12-12
公開日2002-12-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Discovery and structure of a potent and highly specific blocker of insect calcium channels
J.Biol.Chem., 276, 2001
1TVJ
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BU of 1tvj by Molmil
Solution Structure of chick cofilin
分子名称: Cofilin
著者Gorbatyuk, V.Y, Nosworthy, N.J, Robson, S.A, Maciejewski, M.W, dos Remedios, C.G, King, G.F.
登録日2004-06-29
公開日2005-09-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Study of the Molecular Basis for Phosphoinositide Regulation of the Cofilin-Actin Interactions.
To be Published
6OHX
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BU of 6ohx by Molmil
Solution structure of scorpion Hottentotta jayakari venom toxin Hj1a
分子名称: Venom toxin Hj1a
著者Chin, Y.K.-Y, Chow, C.Y, King, G.F.
登録日2019-04-08
公開日2020-02-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Venom Peptides with Dual Modulatory Activity on the Voltage-Gated Sodium Channel NaV1.1 Provide Novel Leads for Development of Antiepileptic Drugs.
Acs Pharmacol Transl Sci, 3, 2020

 

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