8BF8
 
 | | ISDra2 TnpB in complex with reRNA | | 分子名称: | Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB | | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D. | | 登録日 | 2022-10-24 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
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8EXA
 | | ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 1 (RuvC domain resolved) | | 分子名称: | DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB | | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V. | | 登録日 | 2022-10-25 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
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8EX9
 | | ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved) | | 分子名称: | DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB | | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V. | | 登録日 | 2022-10-25 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
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8PM4
 | | Cryo-EM structure of the Cas12m-crRNA-target DNA complex | | 分子名称: | DNA oligoduplex, non-target strand, chain D, ... | | 著者 | Sasnauskas, G, Tamulaitiene, G, Karvelis, T, Bigelyte, G, Siksnys, V. | | 登録日 | 2023-06-28 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing.
Nucleic Acids Res., 52, 2024
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