4PM0
 
 | | PDE7A catalytic domain in complex with 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivative | | 分子名称: | 2-(cyclopentylamino)-3-ethyl-7-ethynylthieno[3,2-d]pyrimidin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | | 著者 | Kawai, K, Endo, Y, Asano, T, Amano, S, Sawada, K, Ueo, N, Takahashi, N, Sonoda, Y, Kamei, N, Nagata, N. | | 登録日 | 2014-05-20 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Discovery of 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one Derivatives as a New Series of Potent Phosphodiesterase 7 Inhibitors.
J.Med.Chem., 57, 2014
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2EC2
 | | Crystal structure of transposase from Sulfolobus tokodaii | | 分子名称: | 136aa long hypothetical transposase, SULFATE ION | | 著者 | Kawai, K, Suzuki, A, Kuramitsu, S, Masui, R, Yamane, T. | | 登録日 | 2007-02-09 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of transposase from Sulfolobus tokodaii
To be Published
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7EKD
 | | Crystal structure of gibberellin 3-oxidase 2 (GA3ox2) in rice | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-OXOGLUTARIC ACID, Gibberellin 3-beta-dioxygenase 2, ... | | 著者 | Takehara, S, Kawai, K, Mikami, B, Ueguchi-Tanaka, M. | | 登録日 | 2021-04-05 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Evolutionary alterations in gene expression and enzymatic activities of gibberellin 3-oxidase 1 in Oryza.
Commun Biol, 5, 2022
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4Y2B
 | | Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one bound to PDE7A | | 分子名称: | 3-ethyl-2-(propan-2-ylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | | 著者 | Endo, Y, Kawai, K, Asano, T, Amano, S, Asanuma, Y, Sawada, K, Onodera, Y, Ueo, N, Takahashi, N, Sonoda, Y, Kamei, N, Irie, T. | | 登録日 | 2015-02-09 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy
Bioorg.Med.Chem.Lett., 25, 2015
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1TNE
 | | NMR STUDY OF Z-DNA AT PHYSIOLOGICAL SALT CONDITIONS, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | DNA (5'-D(*CP*GP*CP*(8MG)P*CP*G)-3') | | 著者 | Robinson, H, Wang, A.H.-J, Sugiyama, H, Kawai, K, Matsunaga, A, Fujimoto, K, Saito, I. | | 登録日 | 1996-02-13 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthesis, structure and thermodynamic properties of 8-methylguanine-containing oligonucleotides: Z-DNA under physiological salt conditions.
Nucleic Acids Res., 24, 1996
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3A7S
 | | Catalytic domain of UCH37 | | 分子名称: | CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | | 著者 | Nishio, K, Kim, S.W, Kawai, K, Mizushima, T, Yamane, T, Hamazaki, J, Murata, S, Tanaka, K. | | 登録日 | 2009-10-04 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain
Biochem.Biophys.Res.Commun., 2009
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7YE3
 | | Crystal structure of Lactobacillus rhamnosus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI complexed with MES | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, ZINC ION | | 著者 | Yamamoto, Y, Oiki, S, Takase, R, Mikami, B, Hashimoto, W. | | 登録日 | 2022-07-05 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | | 主引用文献 | Crystal Structures of Lacticaseibacillus 4-Deoxy-L- threo- 5-hexosulose-uronate Ketol-isomerase KduI in Complex with Substrate Analogs.
J Appl Glycosci (1999), 70, 2023
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7YRS
 | | Crystal structure of Lactobacillus rhamnosus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI complexed with MOPS | | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, ZINC ION | | 著者 | Yamamoto, Y, Oiki, S, Takase, R, Mikami, B, Hashimoto, W. | | 登録日 | 2022-08-10 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Crystal Structures of Lacticaseibacillus 4-Deoxy-L- threo- 5-hexosulose-uronate Ketol-isomerase KduI in Complex with Substrate Analogs.
J Appl Glycosci (1999), 70, 2023
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7VGK
 | | Crystal structure of Lactobacillus rhamnosus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI | | 分子名称: | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase | | 著者 | Iwase, H, Oiki, S, Mikami, B, Takase, R, Hashimoto, W. | | 登録日 | 2021-09-16 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structures of Lacticaseibacillus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI in complex with substrate analogs
J.Appl.Glyosci., 2023
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3ALP
 | | Cell adhesion protein | | 分子名称: | CITRIC ACID, HEXANE-1,6-DIOL, Poliovirus receptor-related protein 1 | | 著者 | Narita, H, Nakagawa, A, Suzuki, M. | | 登録日 | 2010-08-05 | | 公開日 | 2011-02-16 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | | 主引用文献 | Crystal Structure of the cis-Dimer of Nectin-1: implications for the architecture of cell-cell junctions
J.Biol.Chem., 286, 2011
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7E4S
 | | Crystal structure of Lactobacillus rhamnosus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI complexed with HEPES | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-dehydro-4-deoxy-D-glucuronate isomerase, ZINC ION | | 著者 | Yamamoto, Y, Takase, R, Mikami, B, Hashimoto, W. | | 登録日 | 2021-02-15 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Crystal structures of Lacticaseibacillus 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI in complex with substrate analogs
J.Appl.Glyosci., 2023
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