7CM8
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![BU of 7cm8 by Molmil](/molmil-images/mine/7cm8) | High resolution crystal structure of M92A mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae | 分子名称: | Cysteine synthase, GLYCEROL, SODIUM ION | 著者 | Kaushik, A, Rahisuddin, R, Saini, N, Kumaran, S. | 登録日 | 2020-07-25 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular mechanism of selective substrate engagement and inhibitor disengagement of cysteine synthase. J.Biol.Chem., 296, 2020
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4ORE
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![BU of 4ore by Molmil](/molmil-images/mine/4ore) | |
5DBH
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![BU of 5dbh by Molmil](/molmil-images/mine/5dbh) | |
4RUH
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![BU of 4ruh by Molmil](/molmil-images/mine/4ruh) | Crystal structure of Human Carnosinase-2 (CN2) in complex with inhibitor, Bestatin at 2.25 A | 分子名称: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Cytosolic non-specific dipeptidase, GLYCEROL, ... | 著者 | pandya, V, Kaushik, A, Singh, A.K, Singh, R.P, Kumaran, S. | 登録日 | 2014-11-19 | 公開日 | 2015-11-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of Human Carnosinase-2 (CN2) in complex with inhibitor, Bestatin at 2.25 A TO BE PUBLISHED
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4ZU6
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![BU of 4zu6 by Molmil](/molmil-images/mine/4zu6) | Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with pre-reactive o-acetyl serine, alpha-aminoacrylate reaction intermediate and Peptide inhibitor at the resolution of 2.25A | 分子名称: | C-terminal peptide from Serine acetyltransferase, Cysteine synthase, O-ACETYLSERINE, ... | 著者 | Ekka, M.K, Singh, A.K, Kaushik, A, Kumaran, S. | 登録日 | 2015-05-15 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus inuen-zae in complex with pre-reactive o-acetyl serine and peptide inhibitor To Be Published
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4ZU1
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![BU of 4zu1 by Molmil](/molmil-images/mine/4zu1) | Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus influenzae in complex with O-acetyl serine and peptide inhibitor | 分子名称: | C-terminal peptide from Serine acetyltransferase, Cysteine synthase, GLYCEROL, ... | 著者 | Ekka, M.K, Singh, A.K, Kaushik, A, Kumaran, S. | 登録日 | 2015-05-15 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Crystal Structure of O-Acetylserine Sulfhydrylase from Haemophilus inuen-zae in complex with O-acetyl serine and peptide inhibitor To Be Published
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7MD9
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![BU of 7md9 by Molmil](/molmil-images/mine/7md9) | |
7MD1
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![BU of 7md1 by Molmil](/molmil-images/mine/7md1) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCQ
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![BU of 7mcq by Molmil](/molmil-images/mine/7mcq) | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, AOAA-bound enzyme in dimeric form | 分子名称: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCN
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![BU of 7mcn by Molmil](/molmil-images/mine/7mcn) | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme with High HEPES | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCB
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![BU of 7mcb by Molmil](/molmil-images/mine/7mcb) | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase Holoenzyme | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-01 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCP
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![BU of 7mcp by Molmil](/molmil-images/mine/7mcp) | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme dimer | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MD6
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![BU of 7md6 by Molmil](/molmil-images/mine/7md6) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant co-crystallized with NL1 | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, CITRATE ANION, N-[(6-bromo-1H-indol-1-yl)acetyl]glycine, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-03 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCT
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![BU of 7mct by Molmil](/molmil-images/mine/7mct) | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL1 | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, N-[(6-bromo-1H-indol-1-yl)acetyl]glycine, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MDB
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![BU of 7mdb by Molmil](/molmil-images/mine/7mdb) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant co-crystallized with NL2 | 分子名称: | 5-[(6-bromo-1H-indol-1-yl)methyl]-2-methylfuran-3-carboxylic acid, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, CACODYLATE ION, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-03 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MD0
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![BU of 7md0 by Molmil](/molmil-images/mine/7md0) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme in the presence of NL1F3 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCL
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![BU of 7mcl by Molmil](/molmil-images/mine/7mcl) | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, PLP bound | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCY
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![BU of 7mcy by Molmil](/molmil-images/mine/7mcy) | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL3 | 分子名称: | 3-{[6-(7-chloro-1-benzothiophen-2-yl)-1H-indol-1-yl]methyl}-1H-pyrazole-5-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MCU
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![BU of 7mcu by Molmil](/molmil-images/mine/7mcu) | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL2 | 分子名称: | 5-[(6-bromo-1H-indol-1-yl)methyl]-2-methylfuran-3-carboxylic acid, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, CITRATE ANION, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-02 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MD8
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![BU of 7md8 by Molmil](/molmil-images/mine/7md8) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant co-crystallized with NL2 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-03 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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7MDA
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![BU of 7mda by Molmil](/molmil-images/mine/7mda) | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant co-crystallized with NL1 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, N-[(6-bromo-1H-indol-1-yl)acetyl]glycine, ... | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | 登録日 | 2021-04-03 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance. Science, 372, 2021
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6AIF
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![BU of 6aif by Molmil](/molmil-images/mine/6aif) | |
4NU8
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![BU of 4nu8 by Molmil](/molmil-images/mine/4nu8) | |
6VCK
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![BU of 6vck by Molmil](/molmil-images/mine/6vck) | Crystal structure of E.coli RppH-DapF in complex with GDP, Mg2+ and F- | 分子名称: | CHLORIDE ION, Diaminopimelate epimerase, FLUORIDE ION, ... | 著者 | Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A. | 登録日 | 2019-12-21 | 公開日 | 2020-02-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res., 48, 2020
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6VCP
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![BU of 6vcp by Molmil](/molmil-images/mine/6vcp) | Crystal structure of E.coli RppH in complex with UTP | 分子名称: | RNA pyrophosphohydrolase, URIDINE 5'-TRIPHOSPHATE | 著者 | Gao, A, Vasilyev, N, Kaushik, A, Duan, W, Serganov, A. | 登録日 | 2019-12-21 | 公開日 | 2020-02-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res., 48, 2020
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