1IST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ist by Molmil](/molmil-images/mine/1ist) | |
7XGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xgo by Molmil](/molmil-images/mine/7xgo) | Human renin in complex with compound2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND | 著者 | Kashima, A. | 登録日 | 2022-04-05 | 公開日 | 2022-08-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors. Acs Med.Chem.Lett., 13, 2022
|
|
7XGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xgk by Molmil](/molmil-images/mine/7xgk) | Human renin in complex with compound1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND | 著者 | Kashima, A. | 登録日 | 2022-04-05 | 公開日 | 2022-08-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of Novel 2-Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors. Acs Med.Chem.Lett., 13, 2022
|
|
7XGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xgp by Molmil](/molmil-images/mine/7xgp) | Human renin in complex with compound3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, UNKNOWN LIGAND | 著者 | Kashima, A. | 登録日 | 2022-04-05 | 公開日 | 2022-09-07 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of SPH3127: A Novel, Highly Potent, and Orally Active Direct Renin Inhibitor. J.Med.Chem., 65, 2022
|
|
8YVG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yvg by Molmil](/molmil-images/mine/8yvg) | canine immunoproteasome 20S subunit in complex with compound 1 | 分子名称: | Proteasome subunit alpha type, Proteasome subunit beta, Proteasome subunit beta type-8, ... | 著者 | Kashima, A, Arai, Y. | 登録日 | 2024-03-28 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
|
|
8YSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ysx by Molmil](/molmil-images/mine/8ysx) | canine immunoproteasome 20S subunit in complex with compound 2 | 分子名称: | Proteasome subunit alpha type, Proteasome subunit beta, Proteasome subunit beta type-8, ... | 著者 | Kashima, A, Arai, Y. | 登録日 | 2024-03-24 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
|
|
8YVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yvp by Molmil](/molmil-images/mine/8yvp) | canine immunoproteasome 20S subunit in complex with compound 1 | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Kashima, A, Arai, Y. | 登録日 | 2024-03-29 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
|
|
8YPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ypk by Molmil](/molmil-images/mine/8ypk) | mouse proteasome 20S subunit in complex with compound 1 | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Kashima, A, Arai, Y. | 登録日 | 2024-03-17 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
|
|
1AB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ab9 by Molmil](/molmil-images/mine/1ab9) | CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN | 分子名称: | GAMMA-CHYMOTRYPSIN, PENTAPEPTIDE (TPGVY), SULFATE ION | 著者 | Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y. | 登録日 | 1997-02-05 | 公開日 | 1997-08-20 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction. Eur.J.Biochem., 255, 1998
|
|
1AFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1afq by Molmil](/molmil-images/mine/1afq) | CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN COMPLEXED WITH A SYNTHETIC INHIBITOR | 分子名称: | BOVINE GAMMA-CHYMOTRYPSIN, D-leucyl-N-(4-fluorobenzyl)-L-phenylalaninamide, SULFATE ION | 著者 | Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y. | 登録日 | 1997-03-12 | 公開日 | 1997-09-17 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction. Eur.J.Biochem., 255, 1998
|
|
1WRM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wrm by Molmil](/molmil-images/mine/1wrm) | Crystal structure of JSP-1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, dual specificity phosphatase 22 | 著者 | Yokota, T, Kashima, A, Kato, R, Sugio, S. | 登録日 | 2004-10-22 | 公開日 | 2005-10-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution Proteins, 66, 2006
|
|
2DAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dab by Molmil](/molmil-images/mine/2dab) | L201A MUTANT OF D-AMINO ACID AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE | 分子名称: | D-AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Sugio, S, Kashima, A, Kishimoto, K, Peisach, D, Petsko, G.A, Ringe, D, Yoshimura, T, Esaki, N. | 登録日 | 1997-11-30 | 公開日 | 1998-06-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination. Protein Eng., 11, 1998
|
|
1A0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a0g by Molmil](/molmil-images/mine/1a0g) | L201A MUTANT OF D-AMINO ACID AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAMINE-5'-PHOSPHATE | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, D-AMINO ACID AMINOTRANSFERASE | 著者 | Sugio, S, Kashima, A, Kishimoto, K, Peisach, D, Petsko, G.A, Ringe, D, Yoshimura, T, Esaki, N. | 登録日 | 1997-11-30 | 公開日 | 1998-06-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination. Protein Eng., 11, 1998
|
|
2E1M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e1m by Molmil](/molmil-images/mine/2e1m) | Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-glutamate oxidase, PHOSPHATE ION | 著者 | Sasaki, C, Kashima, A, Sakaguchi, C, Mizuno, H, Arima, J, Kusakabe, H, Tamura, T, Sugio, S, Inagaki, K. | 登録日 | 2006-10-26 | 公開日 | 2007-11-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural characterization of l-glutamate oxidase from Streptomyces sp. X-119-6 Febs J., 276, 2009
|
|
1AO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ao6 by Molmil](/molmil-images/mine/1ao6) | |
1BM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bm0 by Molmil](/molmil-images/mine/1bm0) | CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN | 分子名称: | SERUM ALBUMIN | 著者 | Sugio, S, Kashima, A, Mochizuki, S, Noda, M, Kobayashi, K. | 登録日 | 1998-07-28 | 公開日 | 1999-07-28 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human serum albumin at 2.5 A resolution. Protein Eng., 12, 1999
|
|
1QCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qcm by Molmil](/molmil-images/mine/1qcm) | AMYLOID BETA PEPTIDE (25-35), NMR, 20 STRUCTURES | 分子名称: | AMYLOID BETA PEPTIDE | 著者 | Kohno, T, Kobayashi, K, Maeda, T, Sato, K, Takashima, A. | 登録日 | 1996-07-19 | 公開日 | 1997-07-07 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structures of the amyloid beta peptide (25-35) in membrane-mimicking environment. Biochemistry, 35, 1996
|
|
4YVF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yvf by Molmil](/molmil-images/mine/4yvf) | Structure of S-adenosyl-L-homocysteine hydrolase | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{[5-chloro-2-(4-chlorophenoxy)phenyl](2-{[2-(methylamino)ethyl]amino}-2-oxoethyl)amino}-N-(1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide, Adenosylhomocysteinase | 著者 | Akiko, K. | 登録日 | 2015-03-20 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. Bioorg.Med.Chem., 23, 2015
|
|
5AWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5aww by Molmil](/molmil-images/mine/5aww) | Precise Resting State of Thermus thermophilus SecYEG | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Protein translocase subunit SecE, Protein translocase subunit SecY, ... | 著者 | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | 登録日 | 2015-07-10 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.724 Å) | 主引用文献 | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
|
|
5CH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ch4 by Molmil](/molmil-images/mine/5ch4) | Peptide-Bound State of Thermus thermophilus SecYEG | 分子名称: | Protein translocase subunit SecE, Protein translocase subunit SecY, Putative preprotein translocase, ... | 著者 | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | 登録日 | 2015-07-10 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State. Cell Rep, 13, 2015
|
|
5MBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mbx by Molmil](/molmil-images/mine/5mbx) | Crystal structure of reduced murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, ... | 著者 | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | 登録日 | 2016-11-09 | 公開日 | 2017-01-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
|
|
5LFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lfo by Molmil](/molmil-images/mine/5lfo) | Crystal structure of murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, ... | 著者 | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | 登録日 | 2016-07-04 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
|
|
5LGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lgb by Molmil](/molmil-images/mine/5lgb) | Crystal structure of murine N1-acetylpolyamine oxidase in complex with MDL72527 | 分子名称: | FAD-MDL72527 adduct, N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | 著者 | Sjogren, T, Aagaard, A, Wassvik, C, Snijder, A, Barlind, L. | 登録日 | 2016-07-06 | 公開日 | 2017-08-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
|
|
5LAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lae by Molmil](/molmil-images/mine/5lae) | Crystal structure of murine N1-acetylpolyamine oxidase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase,Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | 著者 | Sjogren, T, Aagaard, A, Snijder, A, Barlind, L. | 登録日 | 2016-06-14 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Structure of Murine N(1)-Acetylspermine Oxidase Reveals Molecular Details of Vertebrate Polyamine Catabolism. Biochemistry, 56, 2017
|
|