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2A5W
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BU of 2a5w by Molmil
Crystal structure of the oxidized gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus
分子名称: SULFATE ION, sulfite reductase, desulfoviridin-type subunit gamma (dsvC)
著者Mander, G.J, Weiss, M.S, Hedderich, R, Kahnt, J, Ermler, U, Warkentin, E.
登録日2005-07-01
公開日2005-09-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray structure of the gamma-subunit of a dissimilatory sulfite reductase: Fixed and flexible C-terminal arms.
Febs Lett., 579, 2005
4KPU
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BU of 4kpu by Molmil
Electron transferring flavoprotein of Acidaminococcus fermentans: Towards a mechanism of flavin-based electron bifurcation
分子名称: CHLORIDE ION, Electron transfer flavoprotein alpha subunit, Electron transfer flavoprotein alpha/beta-subunit, ...
著者Mowafy, A.M, Chowdhury, N.P, Demmer, J, Upadhyay, V, Kolzer, S, Jayamani, E, Kahnt, J, Demmer, U, Ermler, U, Buckel, W.
登録日2013-05-14
公開日2014-01-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans.
J.Biol.Chem., 289, 2014
4L2I
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BU of 4l2i by Molmil
Electron transferring flavoprotein of Acidaminococcus fermentans: Towards a mechanism of flavin-based electron bifurcation
分子名称: CHLORIDE ION, Electron transfer flavoprotein alpha subunit, Electron transfer flavoprotein alpha/beta-subunit, ...
著者Mowafy, A.M, Chowdhury, N.P, Demmer, J, Upadhyay, V, Kolzer, S, Jayamani, E, Kahnt, J, Demmer, U, Ermler, U, Buckel, W.
登録日2013-06-04
公開日2014-01-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans.
J.Biol.Chem., 289, 2014
4L1F
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BU of 4l1f by Molmil
Electron transferring flavoprotein of Acidaminococcus fermentans: Towards a mechanism of flavin-based electron bifurcation
分子名称: 1,3-PROPANDIOL, Acyl-CoA dehydrogenase domain protein, COENZYME A PERSULFIDE, ...
著者Mowafy, A.M, Chowdhury, N.P, Demmer, J, Upadhyay, V, Kolzer, S, Jayamani, E, Kahnt, J, Demmer, U, Ermler, U, Buckel, W.
登録日2013-06-03
公開日2014-01-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans.
J.Biol.Chem., 289, 2014
6HUZ
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HmdII from Desulfurobacterium thermolithotrophum reconstituted with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form B
分子名称: 1,2-ETHANEDIOL, 5,10-Methenyltetrahydrofolate, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, ...
著者Watanabe, T, Wagner, T, Huang, G, Kahnt, J, Ataka, K, Ermler, U, Shima, S.
登録日2018-10-09
公開日2019-01-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates.
Angew. Chem. Int. Ed. Engl., 58, 2019
6HUY
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HmdII from Desulfurobacterium thermolithotrophum reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form A
分子名称: 5,10-Methenyltetrahydrofolate, Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, DIMETHYL SULFOXIDE, ...
著者Watanabe, T, Wagner, T, Huang, G, Kahnt, J, Ataka, K, Ermler, U, Shima, S.
登録日2018-10-09
公開日2019-01-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates.
Angew. Chem. Int. Ed. Engl., 58, 2019
6HUX
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HmdII from Methanocaldococcus jannaschii reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydromethanopterin at 2.5 A resolution
分子名称: 1,2-ETHANEDIOL, 1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol, ACETATE ION, ...
著者Watanabe, T, Wagner, T, Huang, G, Kahnt, J, Ataka, K, Ermler, U, Shima, S.
登録日2018-10-09
公開日2019-01-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates.
Angew. Chem. Int. Ed. Engl., 58, 2019
7NB6
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BU of 7nb6 by Molmil
Structure of the autoinducer-2 exporter TqsA from E. coli
分子名称: AI-2 transport protein TqsA
著者Khera, R, Xie, H, Michel, H.
登録日2021-01-25
公開日2022-05-11
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism.
Embo J., 41, 2022
6EQO
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BU of 6eqo by Molmil
Tri-functional propionyl-CoA synthase of Erythrobacter sp. NAP1 with bound NADP+ and phosphomethylphosphonic acid adenylate ester
分子名称: Acetyl-coenzyme A synthetase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Zarzycki, J, Bernhardsgruetter, I, Voegeli, B, Wagner, T, Engilberge, S, Girard, E, Shima, S, Erb, T.J.
登録日2017-10-13
公開日2018-10-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite.
Nat. Chem. Biol., 14, 2018
3SQG
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BU of 3sqg by Molmil
Crystal structure of a methyl-coenzyme M reductase purified from Black Sea mats
分子名称: (17[2]S)-17[2]-methylthio-coenzyme F43, 1-THIOETHANESULFONIC ACID, CALCIUM ION, ...
著者Shima, S, Krueger, M, Weinert, T, Demmer, U, Thauer, R.K, Ermler, U.
登録日2011-07-05
公開日2011-11-30
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a methyl-coenzyme M reductase from Black Sea mats that oxidize methane anaerobically.
Nature, 481, 2011
3WB1
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HcgB from Methanocaldococcus jannaschii
分子名称: SULFATE ION, Uncharacterized protein MJ0488
著者Tamura, H, Fujishiro, T, Ermler, U, Shima, S.
登録日2013-05-11
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of the HcgB enzyme in [Fe]-hydrogenase-cofactor biosynthesis.
Angew.Chem.Int.Ed.Engl., 52, 2013
3WV7
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HcgE from Methanothermobacter marburgensis
分子名称: ADENOSINE-5'-DIPHOSPHATE, Hmd co-occurring protein HcgE
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2014-05-16
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor
Nat Commun, 6, 2015
3WB0
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BU of 3wb0 by Molmil
HcgB from Methanocaldococcus jannaschii in complex with light-decomposed FeGP cofactor of [Fe]-hydrogenase
分子名称: 5'-O-[(S)-{[2-(carboxymethyl)-6-hydroxy-3,5-dimethylpyridin-4-yl]oxy}(hydroxy)phosphoryl]guanosine, Uncharacterized protein MJ0488
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2013-05-10
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Identification of the HcgB enzyme in [Fe]-hydrogenase-cofactor biosynthesis.
Angew.Chem.Int.Ed.Engl., 52, 2013
3WV9
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Guanylylpyridinol (GP)- and ATP-bound HcgE from Methanothermobacter marburgensis
分子名称: 5'-O-[(S)-{[2-(carboxymethyl)-6-hydroxy-3,5-dimethylpyridin-4-yl]oxy}(hydroxy)phosphoryl]guanosine, ADENOSINE-5'-TRIPHOSPHATE, Hmd co-occurring protein HcgE, ...
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2014-05-16
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor
Nat Commun, 6, 2015
3WV8
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BU of 3wv8 by Molmil
ATP-bound HcgE from Methanothermobacter marburgensis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Hmd co-occurring protein HcgE, SULFATE ION
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2014-05-16
公開日2015-04-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor
Nat Commun, 6, 2015
3WB2
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BU of 3wb2 by Molmil
HcgB from Methanocaldococcus jannaschii in complex with the guanylyl-pyridinol product in a model reaction of [Fe]-hydrogenase cofactor biosynthesis
分子名称: 5'-O-[(R)-[(3,6-dimethyl-2-oxo-1,2-dihydropyridin-4-yl)oxy](hydroxy)phosphoryl]guanosine, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2013-05-11
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Identification of the HcgB enzyme in [Fe]-hydrogenase-cofactor biosynthesis.
Angew.Chem.Int.Ed.Engl., 52, 2013
7OT9
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BU of 7ot9 by Molmil
Structure of the AI-2 exporter family protein YdiK from E. coli
分子名称: AI-2E member YdiK
著者Khera, R, Xie, H, Michel, H.
登録日2021-06-09
公開日2022-05-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism.
Embo J., 41, 2022
8QMQ
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BU of 8qmq by Molmil
Succinic semialdehyde dehydrogenase from E. coli with bound NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Succinate semialdehyde dehydrogenase [NAD(P)+] Sad
著者He, H, Zarzycki, J, Erb, T.J.
登録日2023-09-25
公開日2024-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies.
Nat Commun, 15, 2024
8QMR
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Succinic semialdehyde dehydrogenase from E. coli with bound NAD+ and succinic semialdehyde
分子名称: 4-oxobutanoic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Succinate semialdehyde dehydrogenase [NAD(P)+] Sad
著者He, H, Zarzycki, J, Erb, T.J.
登録日2023-09-25
公開日2024-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies.
Nat Commun, 15, 2024
8QMT
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Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+, succinic semialdehyde
分子名称: 4-oxobutanoic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Succinate semialdehyde dehydrogenase [NAD(P)+] Sad
著者He, H, Zarzycki, J, Erb, T.J.
登録日2023-09-25
公開日2024-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies.
Nat Commun, 15, 2024
8QMS
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BU of 8qms by Molmil
Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Succinate semialdehyde dehydrogenase [NAD(P)+] Sad
著者He, H, Zarzycki, J, Erb, T.J.
登録日2023-09-25
公開日2024-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies.
Nat Commun, 15, 2024
4YTE
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BU of 4yte by Molmil
N-terminal domain of HmdIII from Methanocaldococcus jannaschii
分子名称: H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ0715
著者Fujishiro, T, Ermler, U, Shima, S.
登録日2015-03-17
公開日2016-03-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献N-terminal domain of HmdIII from Methanocaldococcus jannaschii
to be published
5A8K
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METHYL-COENZYME M REDUCTASE FROM METHANOTHERMOBACTER WOLFEII AT 1.4 A RESOLUTION
分子名称: 1-THIOETHANESULFONIC ACID, 2-ETHOXYETHANOL, CALCIUM ION, ...
著者Wagner, T, Ermler, U.
登録日2015-07-16
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Didehydroaspartate Modification in Methyl-Coenzyme M Reductase Catalyzing Methane Formation.
Angew.Chem.Int.Ed.Engl., 55, 2016
5A8W
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METHYL-COENZYME M REDUCTASE II FROM METHANOTHERMOBACTER WOLFEII AT 1. 8 A RESOLUTION
分子名称: 1-THIOETHANESULFONIC ACID, ACETATE ION, Coenzyme B, ...
著者Wagner, T, Ermler, U.
登録日2015-07-17
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Didehydroaspartate Modification in Methyl-Coenzyme M Reductase Catalyzing Methane Formation.
Angew.Chem.Int.Ed.Engl., 55, 2016
8Q3V
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BU of 8q3v by Molmil
Cryo-EM structure of the methanogenic Na+ translocating N5-methyl-H4MPT:CoM methyltransferase complex
分子名称: MAGNESIUM ION, SODIUM ION, Tetrahydromethanopterin S-methyltransferase subunit A 1, ...
著者Aziz, I, Vonck, J, Ermler, U.
登録日2023-08-04
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Structural and mechanistic basis of the central energy-converting methyltransferase complex of methanogenesis.
Proc.Natl.Acad.Sci.USA, 121, 2024

 

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