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1SEB
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BU of 1seb by Molmil
COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB
分子名称: ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ...
著者Jardetzky, T.S, Brown, J.H, Gorga, J.C, Stern, L.J, Urban, R.G, Chi, Y.I, Stauffacher, C, Strominger, J.L, Wiley, D.C.
登録日1995-11-26
公開日1996-06-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Nature, 368, 1994
3MAW
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BU of 3maw by Molmil
Structure of the Newcastle disease virus F protein in the post-fusion conformation
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Jardetzky, T.S, Wen, X.
登録日2010-03-24
公開日2010-05-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Virology, 402, 2010
4DAG
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BU of 4dag by Molmil
Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site
分子名称: Fusion glycoprotein F0, Neutralizing Antibody DS7 heavy chain, Neutralizing Antibody DS7 light chain, ...
著者Jardetzky, T.S, Wen, X.
登録日2012-01-12
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3904 Å)
主引用文献Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.
Nat.Struct.Mol.Biol., 19, 2012
4GIP
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BU of 4gip by Molmil
Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2
著者Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A.
登録日2012-08-08
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
5W0K
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BU of 5w0k by Molmil
Crystal structure of EBV gHgL/CL40/gp42 N-domain
分子名称: CL40 IgG heavy chain, CL40 IgG light chain, Envelope glycoprotein H, ...
著者Sathiyamoorthy, K, Jardetzky, T.S.
登録日2017-05-31
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7RAM
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BU of 7ram by Molmil
Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
分子名称: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
著者Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
登録日2021-07-02
公開日2022-06-08
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
3PHF
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BU of 3phf by Molmil
Crystal Structure of the Epstein-Barr virus gH and gL complex
分子名称: Envelope glycoprotein H, Envelope glycoprotein L
著者Matsuura, H, Kirschner, A.N, Jardetzky, T.S.
登録日2010-11-04
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
8TQK
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BU of 8tqk by Molmil
Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab
分子名称: Fusion glycoprotein F0, Heavy chain Fab rPIV3-18, Light chain Fab rPIV3-28
著者Otrelo-Cardoso, A.R, Jardetzky, T.S.
登録日2023-08-07
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Functional and structural characteristics of human monoclonal antibodies that potently neutralize human parainfluenza virus type 3
To be published
8TQI
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BU of 8tqi by Molmil
Hemagglutinin-neuraminidase from Human parainfluenza virus type 3: complex with rPIV3-23 and rPIV3-28 Fabs
分子名称: Heavy chain Fab rPIV3-23, Heavy chain Fab rPIV3-28, Hemagglutinin-neuraminidase, ...
著者Otrelo-Cardoso, A.R, Jardetzky, T.S.
登録日2023-08-07
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Functional and structural characteristics of human monoclonal antibodies that potently neutralize human parainfluenza virus type 3
To Be Published
2P6A
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BU of 2p6a by Molmil
The structure of the Activin:Follistatin 315 complex
分子名称: Follistatin, Inhibin beta A chain, probable fragment of follistatin
著者Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S.
登録日2007-03-16
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions.
J.Biol.Chem., 282, 2007
4WSG
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BU of 4wsg by Molmil
Crystal Structure of Soluble WR PIV5 F-GCNt
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Poor, T.A, Song, A.S, Welch, B.D, Kors, C.A, Jardetzky, T.S, Lamb, R.A.
登録日2014-10-27
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Soluble WR PIV5 F-GCNt
J.Virol., 89, 2015
6UQR
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BU of 6uqr by Molmil
Complex of IgE and Ligelizumab
分子名称: IgE, Ligelizumab, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tarchevskaya, S.S, Kleinboelting, S, Jardetzky, T.S.
登録日2019-10-21
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6502912 Å)
主引用文献The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Nat Commun, 11, 2020
5U68
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BU of 5u68 by Molmil
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
分子名称: Chimera protein of Fusion glycoprotein F0 and Envelope glycoprotein, MPE8
著者Wen, X, Jardetzky, T.S.
登録日2016-12-07
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.083 Å)
主引用文献Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.
Nat Microbiol, 2, 2017
5T1D
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BU of 5t1d by Molmil
Crystal structure of EBV gHgL/gp42/E1D1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E1D1 IgG2a heavy chain, E1D1 IgG2a light chain, ...
著者Sathiyamoorthy, K, Jardetzky, T.S.
登録日2016-08-18
公開日2016-12-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins.
Nat Commun, 7, 2016
8E2U
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BU of 8e2u by Molmil
HMPV F monomer bound to RSV-199 Fab
分子名称: Fusion glycoprotein F0, RSV-199 heavy chain, RSV-199 light chain
著者Wen, X, Jardetzky, T.S.
登録日2022-08-16
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8EAY
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BU of 8eay by Molmil
HMPV F complex with 4I3 Fab
分子名称: 4I3 heavy chain protein, 4I3 light chain protein, Fusion glycoprotein F0
著者Wen, X, Jardetzky, T.S.
登録日2022-08-30
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8EBP
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BU of 8ebp by Molmil
HMPV F dimer bound to RSV-199 Fab
分子名称: Fusion glycoprotein F0, RSV-199 heavy chain protein, RSV-199 light chain protein
著者Wen, X, Jardetzky, T.S.
登録日2022-08-31
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8DZW
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BU of 8dzw by Molmil
RSV F trimer bound to RSV-199 Fab
分子名称: RSV fusion protein, RSV-199 Heavy chain protein, RSV-199 Light chain protein
著者Wen, X, Jardetzky, T.S.
登録日2022-08-08
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
1F2Q
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BU of 1f2q by Molmil
CRYSTAL STRUCTURE OF THE HUMAN HIGH-AFFINITY IGE RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Garman, S.C, Kinet, J.P, Jardetzky, T.S.
登録日2000-05-28
公開日2000-06-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the human high-affinity IgE receptor.
Cell(Cambridge,Mass.), 95, 1998
1F6A
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Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
著者Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S.
登録日2000-06-20
公開日2000-07-20
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
1FP5
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CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN IGE-FC CEPSILON3-CEPSILON4 FRAGMENT.
分子名称: IGE HEAVY CHAIN EPSILON-1
著者Wurzburg, B.A, Garman, S.C, Jardetzky, T.S.
登録日2000-08-30
公開日2000-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains.
Immunity, 13, 2000
4FZH
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Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase
著者Yuan, P, Paterson, R.G, Leser, G.P, Lamb, R.A, Jardetzky, T.S.
登録日2012-07-06
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5008 Å)
主引用文献Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
Plos Pathog., 8, 2012
4JF7
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Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Welch, B.D, Yuan, P, Bose, S, Kors, C.A, Lamb, R.A, Jardetzky, T.S.
登録日2013-02-27
公開日2013-09-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5018 Å)
主引用文献Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain.
Plos Pathog., 9, 2013
4GT7
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An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation
分子名称: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Wurzburg, B.A, Kim, B.K, Jardetzky, T.S.
登録日2012-08-28
公開日2012-09-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.
J.Biol.Chem., 287, 2012
2B9B
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Structure of the Parainfluenza Virus 5 F Protein in its Metastable, Pre-fusion Conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者Yin, H.-S, Wen, X, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-10-11
公開日2006-01-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Nature, 439, 2006

 

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