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Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor
分子名称:	3-(4-CHLOROPHENYL)QUINOXALINE-5-CARBOXAMIDE, Poly [ADP-ribose] polymerase-1
著者	Iwashita, A, Hattori, K, Yamamoto, H, Ishida, J, Kido, Y, Kamijo, K, Murano, K, Miyake, H, Kinoshita, T, Warizaya, M, Ohkubo, M, Matsuoka, N, Mutoh, S.
登録日	2004-08-20
公開日	2005-03-15
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors. Febs Lett., 579, 2005

Crystal Structure of PPAR-delta complex
分子名称:	Peroxisome proliferator-activated receptor delta, {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
著者	Amano, Y.
登録日	2008-05-16
公開日	2008-06-03
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	PPAR-Delta Activation Contributes to Neuroprotectio Against Thapsigargin-Induced SH-SY5Y Cell Death to be published

Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
分子名称:	5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1
著者	Kinoshita, T.
登録日	2003-08-14
公開日	2004-09-14
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase J.Med.Chem., 47, 2004

Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
分子名称:	2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1
著者	Kinoshita, T.
登録日	2003-08-13
公開日	2004-01-27
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase. Febs Lett., 556, 2004