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4WYM
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BU of 4wym by Molmil
Structural basis of HIV-1 capsid recognition by CPSF6
分子名称: Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6
著者Battacharya, A, Taylor, A.B, Hart, P.J, Ivanov, D.N.
登録日2014-11-17
公開日2014-12-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TKP
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BU of 4tkp by Molmil
Complex of Ubc13 with the RING domain of the TRIM5alpha retroviral restriction factor
分子名称: SULFATE ION, Tripartite motif-containing protein 5, Ubiquitin-conjugating enzyme E2 N, ...
著者Johnson, R, Taylor, A.B, Hart, P.J, Ivanov, D.N.
登録日2014-05-27
公開日2015-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献RING Dimerization Links Higher-Order Assembly of TRIM5 alpha to Synthesis of K63-Linked Polyubiquitin.
Cell Rep, 12, 2015
2LM3
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BU of 2lm3 by Molmil
Structure of the rhesus monkey TRIM5alpha PRYSPRY domain
分子名称: Tripartite motif-containing protein 5
著者Biris, N, Yang, Y, Taylor, A.B, Tomashevski, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D.N.
登録日2011-11-21
公開日2012-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
6U6Z
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BU of 6u6z by Molmil
Human SAMHD1 bound to deoxyribo(TG*TTCA)-oligonucleotide
分子名称: DNA polymer TG(PST)TCA, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION
著者Taylor, A.B, Yu, C.H, Ivanov, D.N.
登録日2019-08-30
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
6U6X
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BU of 6u6x by Molmil
Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide
分子名称: DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION
著者Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N.
登録日2019-08-30
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
6U6Y
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BU of 6u6y by Molmil
Human SAMHD1 bound to ribo(CGCCU)-oligonucleotide
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA CGCCU, ...
著者Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N.
登録日2019-08-30
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
3UV9
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BU of 3uv9 by Molmil
Structure of the rhesus monkey TRIM5alpha deltav1 PRYSPRY domain
分子名称: Tripartite motif-containing protein 5
著者Biris, N, Yang, Y, Taylor, A.B, Tomashevskii, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D.
登録日2011-11-29
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
5JVW
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BU of 5jvw by Molmil
Crystal structure of mithramycin analogue MTM SA-Trp in complex with a 10-mer DNA AGAGGCCTCT.
分子名称: DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Trp, ...
著者Hou, C, Rohr, J, Tsodikov, O.V.
登録日2016-05-11
公開日2016-09-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5VA4
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BU of 5va4 by Molmil
TRIM-Cyclophilin A B-box 2 and coiled-coil chimera
分子名称: TRIM5/cyclophilin A V4 fusion protein, ZINC ION
著者Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O.W.
登録日2017-03-24
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins.
J. Virol., 92, 2018
7JSA
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BU of 7jsa by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the reduced form, in complex with double-stranded DNA ACCGGAAGTG
分子名称: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
著者Hou, C, Tsodikov, O.V.
登録日2020-08-14
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
7JSL
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BU of 7jsl by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the oxidized form, in complex with double-stranded DNA ACCGGAAGTG
分子名称: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
著者Hou, C, Tsodikov, O.V.
登録日2020-08-14
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.51 Å)
主引用文献Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
7LU5
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BU of 7lu5 by Molmil
SAMHD1(113-626) H206R D207N R366H
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
著者Temple, J.T, Bowen, N.E.
登録日2021-02-20
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.57 Å)
主引用文献Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J.Biol.Chem., 297, 2021
7LTT
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BU of 7ltt by Molmil
SAMHD1(113-626) H206R D207N R366C
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION
著者Temple, J.T, Bowen, N.E.
登録日2021-02-20
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
J.Biol.Chem., 297, 2021
4QNB
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BU of 4qnb by Molmil
Disulfide stabilized HIV-1 CA hexamer in complex with PHENYL-L-PHENYLALANINAMIDE inhibitor
分子名称: CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
著者Pornillos, O.
登録日2014-06-17
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
6OW0
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BU of 6ow0 by Molmil
Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+ and PEG
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, MtmW, ...
著者Hou, C, Yu, X, Rohr, J, Tsodikov, O.V.
登録日2019-05-08
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
6OVX
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BU of 6ovx by Molmil
Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+, P422 form
分子名称: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative side chain reductase
著者Hou, C, Yu, X, Rohr, J, Tsodikov, O.V.
登録日2019-05-08
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
6OVQ
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BU of 6ovq by Molmil
Crystal structure of mithramycin 3-side chain keto-reductase MtmW
分子名称: GLYCEROL, Putative Side chain reductase
著者Hou, C, Yu, X, Rohr, J, Tsodikov, O.V.
登録日2019-05-08
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
5JW0
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BU of 5jw0 by Molmil
Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT
分子名称: DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
著者Hou, C, Rohr, J, Tsodikov, O.V.
登録日2016-05-11
公開日2016-09-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JW2
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BU of 5jw2 by Molmil
Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT
分子名称: DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
著者Hou, C, Rohr, J, Tsodikov, O.V.
登録日2016-05-11
公開日2016-09-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JVT
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BU of 5jvt by Molmil
Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer DNA GACCGGAAGTG
分子名称: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ...
著者Hou, C, Tsodikov, O.V.
登録日2016-05-11
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
7ZUD
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BU of 7zud by Molmil
Crystal structure of HIV-1 capsid IP6-CPSF6 complex
分子名称: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE
著者Nicastro, G, Taylor, I.A.
登録日2022-05-12
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022

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