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1WOK
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BU of 1wok by Molmil
Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor
分子名称: 3-(4-CHLOROPHENYL)QUINOXALINE-5-CARBOXAMIDE, Poly [ADP-ribose] polymerase-1
著者Iwashita, A, Hattori, K, Yamamoto, H, Ishida, J, Kido, Y, Kamijo, K, Murano, K, Miyake, H, Kinoshita, T, Warizaya, M, Ohkubo, M, Matsuoka, N, Mutoh, S.
登録日2004-08-20
公開日2005-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors.
Febs Lett., 579, 2005
1UK1
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BU of 1uk1 by Molmil
Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
分子名称: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1
著者Kinoshita, T.
登録日2003-08-14
公開日2004-09-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase
J.Med.Chem., 47, 2004

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件を2024-09-11に公開中

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