7WMC
| Crystal structure of macrocyclic peptide 1 bound to human Nicotinamide N-methyltransferase | 分子名称: | Nicotinamide N-methyltransferase, Peptide1 | 著者 | Yoshida, S, Uehara, S, Kondo, N, Takahashi, Y, Yamamoto, S, Kameda, A, Kawagoe, S, Inoue, N, Yamada, M, Yoshimura, N, Tachibana, Y. | 登録日 | 2022-01-14 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides. J.Med.Chem., 65, 2022
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7WMT
| Crystal structure of small molecule 13 bound to human Nicotinamide N-methyltransferase | 分子名称: | Nicotinamide N-methyltransferase, [(2~{R},4~{S})-4-[2-(aminomethyl)imidazol-1-yl]-2-[1-[(4-chlorophenyl)methyl]-5-methyl-indol-2-yl]pyrrolidin-1-yl]-(1~{H}-pyrrolo[2,3-b]pyridin-5-yl)methanone | 著者 | Yoshida, S, Uehara, S, Kondo, N, Takahashi, Y, Yamamoto, S, Kameda, A, Kawagoe, S, Inoue, N, Yamada, M, Yoshimura, N, Tachibana, Y. | 登録日 | 2022-01-17 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides. J.Med.Chem., 65, 2022
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2Y44
| Crystal structure of GARP from Trypanosoma congolense | 分子名称: | GLUTAMIC ACID/ALANINE-RICH PROTEIN, GLYCEROL, IODIDE ION | 著者 | Loveless, B.C, Mason, J.W, Sakurai, T, Inoue, N, Razavi, M, Pearson, T.W, Boulanger, M.J. | 登録日 | 2011-01-04 | 公開日 | 2011-03-30 | 最終更新日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Characterization and Epitope Mapping of the Glutamic Acid/Alanine-Rich Protein from Trypanosoma Congolense: Defining Assembly on the Parasite Cell Surface. J.Biol.Chem., 286, 2011
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5JKE
| Crystal structure of human IZUMO1-JUNO complex (crystal form 3) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ... | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2016-04-26 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization Nature, 534, 2016
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4WUA
| Crystal structure of human SRPK1 complexed to an inhibitor SRPIN340 | 分子名称: | CITRIC ACID, N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide, SRSF protein kinase 1, ... | 著者 | Hoshina, M, Ikura, T, Hosoya, T, Hagiwara, M, Ito, N. | 登録日 | 2014-10-31 | 公開日 | 2015-09-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice Mol.Pharmacol., 88, 2015
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5JK9
| Crystal structure of human IZUMO1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Izumo sperm-egg fusion protein 1 | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2016-04-26 | 公開日 | 2016-06-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization Nature, 534, 2016
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5JKC
| Crystal structure of human IZUMO1-JUNO complex (crystal form 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ... | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2016-04-26 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization Nature, 534, 2016
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5JKD
| Crystal structure of human IZUMO1-JUNO complex (crystal form 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Izumo sperm-egg fusion protein 1, ... | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2016-04-26 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization Nature, 534, 2016
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5JKB
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5JKA
| Crystal structure of human JUNO (crystal form 1) | 分子名称: | CHLORIDE ION, Sperm-egg fusion protein Juno, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Ohto, U, Ishida, H, Shimizu, T. | 登録日 | 2016-04-26 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization Nature, 534, 2016
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2OCC
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2RMQ
| Solution structure of fully modified 4'-thioDNA with the sequence of d(CGCGAATTCGCG) | 分子名称: | DNA (5'-D(*(C4S)P*(S4G)P*(C4S)P*(S4G)P*(S4A)P*(S4A)P*(T49)P*(T49)P*(C4S)P*(S4G)P*(C4S)P*(S4G))-3') | 著者 | Matsugami, A, Ohyama, T, Inada, M, Katahira, M. | 登録日 | 2007-11-12 | 公開日 | 2008-04-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Unexpected A-form formation of 4'-thioDNA in solution, revealed by NMR, and the implications as to the mechanism of nuclease resistance Nucleic Acids Res., 36, 2008
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1OCO
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1OCZ
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1OCR
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5B5K
| Crystal structure of Izumo1, the mammalian sperm ligand for egg Juno | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Izumo sperm-egg fusion protein 1 | 著者 | Nishimura, K, Han, L, De Sanctis, D, Jovine, L. | 登録日 | 2016-05-11 | 公開日 | 2016-07-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure of sperm Izumo1 reveals unexpected similarities with Plasmodium invasion proteins. Curr.Biol., 26, 2016
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