3KO1
 
 | | Cystal structure of thermosome from Acidianus tengchongensis strain S5 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin | | 著者 | Huo, Y, Zhang, K, Hu, Z, Wang, L, Zhai, Y, Zhou, Q, Lander, G, He, Y, Zhu, J, Xu, W, Dong, Z, Sun, F. | | 登録日 | 2009-11-12 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of group II chaperonin in the open state.
Structure, 18, 2010
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6IQW
 | | Cryo-EM structure of Csm effector complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Csm1, Csm2, ... | | 著者 | Huo, Y, Li, T, Wang, N, Dong, Q, Wang, X, Jiang, T. | | 登録日 | 2018-11-09 | | 公開日 | 2019-01-16 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Cryo-EM structure of Type III-A CRISPR effector complex.
Cell Res., 28, 2018
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7YN9
 | | Cryo-EM structure of Cas7-11-crRNA binary complex | | 分子名称: | CRISPR-associated RAMP family protein, crRNA | | 著者 | Huo, Y, Dong, Q, Zhao, H, Jiang, T. | | 登録日 | 2022-07-30 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
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7YNC
 | | Cryo-EM structure of Cas7-11-crRNA bound to target RNA-3 | | 分子名称: | CRISPR-associated RAMP family protein, Target RNA-3 (28-MER), crRNA (38-MER) | | 著者 | Huo, Y, Dong, Q, Zhao, H, Jiang, T. | | 登録日 | 2022-07-30 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
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7YNA
 | | Cryo-EM structure of Cas7-11-crRNA bound to target RNA-1 | | 分子名称: | CRISPR-associated RAMP family protein, Target RNA-1 (25-MER), crRNA (38-MER) | | 著者 | Huo, Y, Dong, Q, Zhao, H, Jiang, T. | | 登録日 | 2022-07-30 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
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7YNB
 | | Cryo-EM structure of Cas7-11-crRNA bound to target RNA-2 | | 分子名称: | CRISPR-associated RAMP family protein, Target RNA-2 (28-MER), crRNA (38-MER) | | 著者 | Huo, Y, Dong, Q, Zhao, H, Jiang, T. | | 登録日 | 2022-07-30 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
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7YND
 | | Cryo-EM structure of Cas7-11-crRNA-Csx29 ternary complex | | 分子名称: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, crRNA (38-MER) | | 著者 | Huo, Y, Dong, Q, Zhao, H, Jiang, T. | | 登録日 | 2022-07-30 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
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8J4T
 | | GajA-GajB complex | | 分子名称: | Endonuclease GajA, Gabija protein GajB | | 著者 | Wei, T, Ma, J, Huo, Y. | | 登録日 | 2023-04-20 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural and biochemical insights into the mechanism of the Gabija bacterial immunity system.
Nat Commun, 15, 2024
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8WFX
 | | Cryo-EM structure of CRISPR-Csm effector complex from Mycobacterium canettii | | 分子名称: | CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ... | | 著者 | Huo, Y, Ma, X, Jiang, T. | | 登録日 | 2023-09-20 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Type-III-A structure of mycobacteria CRISPR-Csm complexes involving atypical crRNAs.
Int.J.Biol.Macromol., 260, 2024
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4QQW
 | | Crystal structure of T. fusca Cas3 | | 分子名称: | CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | | 著者 | Ke, A, Huo, Y, Nam, K.H. | | 登録日 | 2014-06-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.664 Å) | | 主引用文献 | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
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4QQX
 | | Crystal structure of T. fusca Cas3-ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ... | | 著者 | Ke, A, Huo, Y, Nam, K.H. | | 登録日 | 2014-06-30 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | | 主引用文献 | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
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4QQZ
 | | Crystal structure of T. fusca Cas3-AMPPNP | | 分子名称: | CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | | 著者 | Ke, A, Huo, Y, Nam, K.H. | | 登録日 | 2014-06-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
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4QQY
 | | Crystal structure of T. fusca Cas3-ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ... | | 著者 | Ke, A, Huo, Y, Nam, K.H. | | 登録日 | 2014-06-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
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3QQ2
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4FTH
 | | Crystal Structure of NtrC4 DNA-binding domain bound to double-stranded DNA | | 分子名称: | 5'-D(*AP*CP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*GP*CP*AP*T)-3', 5'-D(P*GP*AP*TP*GP*CP*AP*TP*TP*TP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*AP*A)-3', Transcriptional regulator (NtrC family) | | 著者 | Vidangos, N.K, Heideker, J, Lyubimov, A.Y, Lamers, M, Huo, Y, Pelton, J.G, Ton, J, Gralla, J.D, Kuriyan, J, Berger, J.M, Wemmer, D.E. | | 登録日 | 2012-06-27 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | | 主引用文献 | DNA Recognition by a sigma (54) Transcriptional Activator from Aquifex aeolicus.
J.Mol.Biol., 426, 2014
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5ZB2
 | | Crystal structure of Rad7 and Elc1 complex in yeast | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ... | | 著者 | Jiang, T, Liu, L, Huo, Y. | | 登録日 | 2018-02-09 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.30000544 Å) | | 主引用文献 | Crystal structure of the yeast Rad7-Elc1 complex and assembly of the Rad7-Rad16-Elc1-Cul3 complex.
DNA Repair (Amst.), 77, 2019
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6KBD
 | | fused To-MtbCsm1 with 2dATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION | | 著者 | Li, T, Huo, Y, Jiang, T. | | 登録日 | 2019-06-24 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Int.J.Biol.Macromol., 170, 2020
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6KC0
 | | fused To-MtbCsm1 with 2ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION | | 著者 | Li, T, Huo, Y, Jiang, T. | | 登録日 | 2019-06-26 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Int.J.Biol.Macromol., 170, 2020
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7V3V
 | | Cryo-EM structure of MCM double hexamer bound with DDK in State I | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... | | 著者 | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | | 登録日 | 2021-08-11 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7V3U
 | | Cryo-EM structure of MCM double hexamer with structured Mcm4-NSD | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | | 著者 | Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. | | 登録日 | 2021-08-11 | | 公開日 | 2022-04-13 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase.
Nat Commun, 13, 2022
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7XC6
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7XWY
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7CPU
 | | Cryo-EM structure of 80S ribosome from mouse kidney | | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | | 登録日 | 2020-08-08 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
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7CPV
 | | Cryo-EM structure of 80S ribosome from mouse testis | | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | | 登録日 | 2020-08-08 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
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8X5D
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