4EMV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4emv by Molmil](/molmil-images/mine/4emv) | Crystal structure of a topoisomerase ATP inhibitor | 分子名称: | 5-{2-(ethylcarbamoyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}pyridine-3-carboxylic acid, DNA topoisomerase IV, B subunit | 著者 | Boriack-Sjodin, P.A, Manchester, J, Hull, K. | 登録日 | 2012-04-12 | 公開日 | 2012-08-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg.Med.Chem.Lett., 22, 2012
|
|
3U2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u2d by Molmil](/molmil-images/mine/3u2d) | S. aureus GyrB ATPase domain in complex with small molecule inhibitor | 分子名称: | 4-bromo-5-methyl-N-[1-(3-nitropyridin-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide, DNA gyrase subunit B, MAGNESIUM ION | 著者 | Boriack-Sjodin, P.A, Prince, D.B, Eakin, A.E, Sherer, B.A. | 登録日 | 2011-10-03 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob.Agents Chemother., 56, 2012
|
|
3U2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u2k by Molmil](/molmil-images/mine/3u2k) | S. aureus GyrB ATPase domain in complex with a small molecule inhibitor | 分子名称: | 2-chloro-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)pyridine-4-carboxamide, DNA gyrase subunit B, MAGNESIUM ION | 著者 | Boriack-Sjodin, P.A, Prince, D.B, Eakin, A.E, Sherer, B.A. | 登録日 | 2011-10-03 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob.Agents Chemother., 56, 2012
|
|
6XKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xki by Molmil](/molmil-images/mine/6xki) | Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog | 分子名称: | (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | 著者 | Liang, J, Naineni, S.K, Pelletier, J, Nagar, B. | 登録日 | 2020-06-26 | 公開日 | 2021-01-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A. Cell Chem Biol, 28, 2021
|
|
3TTZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ttz by Molmil](/molmil-images/mine/3ttz) | Crystal structure of a topoisomerase ATPase inhibitor | 分子名称: | 2-[(3S,4R)-4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}-3-fluoropiperidin-1-yl]-1,3-thiazole-5-carboxylic acid, DNA gyrase subunit B, MAGNESIUM ION | 著者 | Boriack-Sjodin, P.A, Read, J, Eakin, A.E, Sherer, B.A. | 登録日 | 2011-09-15 | 公開日 | 2011-11-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacy. Bioorg.Med.Chem.Lett., 21, 2011
|
|
6U9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9u by Molmil](/molmil-images/mine/6u9u) | Structure of GM9_TH8seq732127 FAB | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | 著者 | Singh, S, Liban, T.J, Pancera, M. | 登録日 | 2019-09-09 | 公開日 | 2019-11-06 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
|
|
6U3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u3z by Molmil](/molmil-images/mine/6u3z) | Structure of VD20_5A4 Fab | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Dionne, G, Shapiro, L. | 登録日 | 2019-08-22 | 公開日 | 2019-11-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99002314 Å) | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J.Exp.Med., 217, 2020
|
|
3JZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jz0 by Molmil](/molmil-images/mine/3jz0) | LinB complexed with clindamycin and AMPCPP | 分子名称: | CLINDAMYCIN, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Lincosamide nucleotidyltransferase, ... | 著者 | Morar, M, Wright, G.D. | 登録日 | 2009-09-22 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
|
|
6OL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ol7 by Molmil](/molmil-images/mine/6ol7) | |
3JYY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jyy by Molmil](/molmil-images/mine/3jyy) | SeMet LinB complexed with PPi | 分子名称: | Lincosamide nucleotidyltransferase, MAGNESIUM ION, PYROPHOSPHATE | 著者 | Morar, M, Wright, G.D. | 登録日 | 2009-09-22 | 公開日 | 2009-11-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
|
|
4R73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r73 by Molmil](/molmil-images/mine/4r73) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (endogenous glucose-6-phosphate and mannose-6-phosphate bound) | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, ABC-type Fe3+ transport system, ... | 著者 | Calmettes, C, Tang, C, Sit, B, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
|
|
4R75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r75 by Molmil](/molmil-images/mine/4r75) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous sedoheptulose-7-phosphate bound) | 分子名称: | 1-C-(hydroxymethyl)-6-O-phosphono-beta-D-altrofuranose, ABC-type Fe3+ transport system, periplasmic component, ... | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.278 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
|
|
4R74
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r74 by Molmil](/molmil-images/mine/4r74) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous fructose-6-phosphate bound) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-O-phosphono-beta-D-fructofuranose, ABC-type Fe3+ transport system, ... | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
|
|
4R72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r72 by Molmil](/molmil-images/mine/4r72) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (apo form) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ABC-type Fe3+ transport system, periplasmic component, ... | 著者 | Sit, B, Calmettes, C, Moraes, T.F. | 登録日 | 2014-08-26 | 公開日 | 2015-08-12 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
|
|