1VJY
 
 | | Crystal Structure of a Naphthyridine Inhibitor of Human TGF-beta Type I Receptor | | 分子名称: | 2-[5-(6-METHYLPYRIDIN-2-YL)-2,3-DIHYDRO-1H-PYRAZOL-4-YL]-1,5-NAPHTHYRIDINE, TGF-beta receptor type I | | 著者 | Gellibert, F, Woolven, J, Fouchet, M.-H, Mathews, N, Goodland, H, Lovegrove, V, Laroze, A, Nguyen, V.-L, Sautet, S, Wang, R, Janson, C, Smith, W, Krysa, G, Boullay, V, de Gouville, A.-C, Huet, S, Hartley, D. | | 登録日 | 2004-04-07 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-beta Type I Receptor Inhibitors.
J.Med.Chem., 47, 2004
|
|
1XLY
 | | X-RAY STRUCTURE OF THE RNA-BINDING PROTEIN SHE2p | | 分子名称: | SHE2p | | 著者 | Niessing, D, Huettelmaier, S, Zenklusen, D, Singer, R.H, Burley, S.K. | | 登録日 | 2004-09-30 | | 公開日 | 2004-11-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | She2p is a novel RNA binding protein with a basic helical hairpin motif
Cell(Cambridge,Mass.), 119, 2004
|
|
3GXL
 | | ALK-5 kinase complex with GW857175 | | 分子名称: | N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine, TGF-beta receptor type-1 | | 著者 | Smith, W, Janson, C. | | 登録日 | 2009-04-02 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
|
|
3HMM
 | | Structure of Alk5 + GW855857 | | 分子名称: | 2-(6-methylpyridin-2-yl)-N-pyridin-4-ylquinazolin-4-amine, TGF-beta receptor type-1 | | 著者 | Smith, W, Janson, C. | | 登録日 | 2009-05-29 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
|
|
6FY5
 | |
3DY6
 | | PPARdelta complexed with an anthranilic acid partial agonist | | 分子名称: | 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid, IODIDE ION, Peroxisome proliferator-activated receptor delta | | 著者 | Lambert, M.L, Xu, R, Shearer, B.G, Wilson, T.M. | | 登録日 | 2008-07-25 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of a novel class of PPARdelta partial agonists
Bioorg.Med.Chem.Lett., 18, 2008
|
|
2OB0
 | | Human MAK3 homolog in complex with Acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, Human MAK3 homolog | | 著者 | Walker, J.R, Schuetz, S, Antoshenko, T, Wu, H, Bernstein, G, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2006-12-18 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Human MAK3 homolog
To be Published
|
|
6G03
 | | NMR Solution Structure of yeast TSR2(1-152) | | 分子名称: | Pre-rRNA-processing protein TSR2 | | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | | 登録日 | 2018-03-16 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
|
|
6G04
 | | NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119) | | 分子名称: | 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2 | | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | | 登録日 | 2018-03-16 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
|
|
