1MNV
| Actinomycin D binding to ATGCTGCAT | 分子名称: | 5'-D(*AP*TP*GP*CP*TP*GP*CP*AP*T)-3', ACTINOMYCIN D | 著者 | Hou, M.-H, Robinson, H, Gao, Y.-G, Wang, A.H.-J. | 登録日 | 2002-09-06 | 公開日 | 2002-11-22 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Actinomycin D Bound to the Ctg Triplet Repeat Sequences Linked to Neurological Diseases Nucleic Acids Res., 30, 2002
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7EBL
| Bacterial STING in complex with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), STING | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2021-03-10 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal structure and functional implication of bacterial STING. Nat Commun, 13, 2022
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7EBD
| Bacterial STING in complex with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, TIR-like domain-containing protein | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2021-03-09 | 公開日 | 2021-09-15 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure and functional implication of bacterial STING. Nat Commun, 13, 2022
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6K94
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8JSJ
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8JSK
| Crystal structure of an N-terminal cyclic nucleotide-binding domain of a PycTIR from Pseudovibrio sp. in complex with cUMP | 分子名称: | PycTIR, Uridine-3',5'-cyclic monophosphate | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-06-20 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system. Nat Commun, 15, 2024
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8JSF
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8JSZ
| Crystal structure of a uridylate cyclase from Anabaena sp. | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-06-20 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structural and functional characterization of cyclic pyrimidine-regulated anti-phage system. Nat Commun, 15, 2024
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6K93
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7D4U
| ATP complex with double mutant cyclic trinucleotide synthase CdnD | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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7D48
| apo-form cyclic trinucleotide synthase CdnD | 分子名称: | Cyclic AMP-AMP-GMP synthase, SODIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-23 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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7D4S
| apo-form cyclic trinucleotide synthase CdnD | 分子名称: | Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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7D4O
| cyclic trinucleotide synthase CdnD in complex with ATP and ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ... | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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7D4J
| ddATP complex of cyclic trinucleotide synthase CdnD | 分子名称: | 2',3'-dideoxyadenosine triphosphate, Cyclic AMP-AMP-GMP synthase, MAGNESIUM ION | 著者 | Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y. | 登録日 | 2020-09-24 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase. Nucleic Acids Res., 49, 2021
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8HYK
| CD-NTase EfCdnE in complex with intermediate pppU[2'-5']p | 分子名称: | EfCdnE, MAGNESIUM ION, [[(2R,3R,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-01-06 | 公開日 | 2023-07-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.021 Å) | 主引用文献 | Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases. Nat Commun, 14, 2023
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8HYN
| Bacterial STING from Riemerella anatipestifer | 分子名称: | CD-NTase-associated protein 12, TETRAETHYLENE GLYCOL | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-01-07 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.089 Å) | 主引用文献 | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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8HWJ
| Bacterial STING from Epilithonimonas lactis in complex with 3'3'-c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CD-NTase-associated protein 12 | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2022-12-30 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | 主引用文献 | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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8HWI
| Bacterial STING from Larkinella arboricola in complex with 3'3'-c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12 | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2022-12-30 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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8HY8
| Bacterial STING from Epilithonimonas lactis | 分子名称: | CD-NTase-associated protein 12 | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-01-06 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.568 Å) | 主引用文献 | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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8HY9
| Bacterial STING from Riemerella anatipestifer in complex with 3'3'-c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, CD-NTase-associated protein 12 | 著者 | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2023-01-06 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.462 Å) | 主引用文献 | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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7YIB
| Crystal structure of wild-type Cap4 SAVED domain-containing receptor from Enterobacter cloacae | 分子名称: | CD-NTase-associated protein 4, CHLORIDE ION | 著者 | Ko, T.-P, Yang, C.-S, Hou, M.-H, Wang, Y.-C, Chen, Y. | 登録日 | 2022-07-15 | 公開日 | 2023-05-31 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Specific recognition of cyclic oligonucleotides by Cap4 for phage infection. Int.J.Biol.Macromol., 237, 2023
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7YIA
| Crystal structure of K74A mutant of Cap4 SAVED domain-containing receptor from Enterobacter cloacae | 分子名称: | CD-NTase-associated protein 4, MAGNESIUM ION | 著者 | Ko, T.-P, Yang, C.-S, Hou, M.-H, Wang, Y.-C, Chen, Y. | 登録日 | 2022-07-15 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.428 Å) | 主引用文献 | Specific recognition of cyclic oligonucleotides by Cap4 for phage infection. Int.J.Biol.Macromol., 237, 2023
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