1G5Z
 
 | | CRYSTAL STRUCTURE OF LYME DISEASE ANTIGEN OUTER SURFACE PROTEIN C (OSPC) FROM BORRELIA BURGDORFERI STRAIN N40 | | 分子名称: | OUTER SURFACE PROTEIN C | | 著者 | Eicken, C, Sharma, V, Klabunde, T, Owens, R.T, Pikas, D.S, Hook, M, Sacchettini, J.C. | | 登録日 | 2000-11-02 | | 公開日 | 2001-04-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi.
J.Biol.Chem., 276, 2001
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1N67
 | | Clumping Factor A from Staphylococcus aureus | | 分子名称: | Clumping Factor, MAGNESIUM ION | | 著者 | Deivanayagam, C.C.S, Wann, E.R, Chen, W, Carson, M, Rajashankar, K.R, Hook, M, Narayana, S.V.L. | | 登録日 | 2002-11-08 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel variant of the immunoglobulin fold in surface adhesins of
Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM,
clumping factor A
Embo J., 21, 2002
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1D2P
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1D2O
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1O9A
 | | Solution structure of the complex of 1F12F1 from fibronectin with B3 from FnBB from S. dysgalactiae | | 分子名称: | FIBRONECTIN, FIBRONECTIN BINDING PROTEIN | | 著者 | Schwarz-Linek, U, Werner, J.M, Pickford, A.R, Pilka, E.S, Gurusiddappa, S, Briggs, J.A.G, Hook, M, Campbell, I.D, Potts, J.R. | | 登録日 | 2002-12-11 | | 公開日 | 2003-05-08 | | 最終更新日 | 2018-01-24 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper.
Nature, 423, 2003
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1R17
 | | Crystal Structure Analysis of S.epidermidis adhesin SdrG binding to Fibrinogen (adhesin-ligand complex) | | 分子名称: | CALCIUM ION, fibrinogen-binding protein SdrG, fibrinopeptide B | | 著者 | Ponnuraj, K, Bowden, M.G, Davis, S, Gurusiddappa, S, Moore, D, Choe, D, Xu, Y, Hook, M, Narayana, S.V.L. | | 登録日 | 2003-09-23 | | 公開日 | 2003-10-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
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1R19
 | | Crystal Structure Analysis of S.epidermidis adhesin SdrG binding to Fibrinogen (Apo structure) | | 分子名称: | fibrinogen-binding protein SdrG | | 著者 | Ponnuraj, K, Bowden, M.G, Davis, S, Gurusiddappa, S, Moore, D, Choe, D, Xu, Y, Hook, M, Narayana, S.V.L. | | 登録日 | 2003-09-23 | | 公開日 | 2003-10-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | | 主引用文献 | A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
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2VR3
 | | Structural and Biochemical Characterization of Fibrinogen binding to ClfA from Staphylocccus aureus | | 分子名称: | CLUMPING FACTOR A, FIBRINOGEN GAMMA-CHAIN | | 著者 | Ganesh, V.K, Rivera, J.J, Smeds, E, Bowden, M.G, Wann, E.R, Gurusidappa, S, Fitzgerald, J.R, Hook, M. | | 登録日 | 2008-03-25 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Structural Model of the Staphylococcus Aureus Clfa-Fibrinogen Interaction Opens New Avenues for the Design of Anti-Staphylococcal Therapeutics.
Plos Pathog., 4, 2008
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2RAL
 | | Crystal Structure Analysis of double cysteine mutant of S.epidermidis adhesin SdrG: Evidence for the Dock,Lock and Latch ligand binding mechanism | | 分子名称: | Serine-aspartate repeat-containing protein G | | 著者 | Ponnuraj, K, Sthanam, N, Bowden, M.G, Hook, M. | | 登録日 | 2007-09-17 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.
J.Biol.Chem., 283, 2008
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3AU0
 | | Structural and biochemical characterization of ClfB:ligand interactions | | 分子名称: | Clumping factor B, MAGNESIUM ION | | 著者 | Ganesh, V.K, Barbu, E.M, Deivanayagam, C.C.S, Le, B, Anderson, A.S, Matsuka, Y, Lin, S.L, Foster, T.F, Narayana, S.V.L, Hook, M. | | 登録日 | 2011-01-28 | | 公開日 | 2011-05-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural and biochemical characterization of ClfB:ligand interactions
To be published
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7ZJP
 | | Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106 | | 分子名称: | 2-methyl-4-[4-(trifluoromethyl)phenyl]pyrazolo[3,4-b]indole-7-carboxylic acid, SULFATE ION, Transcriptional enhancer factor TEF-1 | | 著者 | Freire, F, Heinrich, T, Petersson, C, Schneider, R, Garg, S, Schwarz, D, Gunera, J, Seshire, A, Koetzner, L, Schlesiger, S, Musil, D, Schilke, H, Doerfel, B, Diehl, P, Boepple, P, Lemos, A.R, Sousa, P.M.F, Freire, F, Bandeiras, T.M, Carswell, E, Pearson, N, Sirohi, S, Hooker, M, Trivier, E, Broome, R, Balsiger, A, Crowden, A, Dillon, C, Wienke, D. | | 登録日 | 2022-04-11 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106 .
J.Med.Chem., 65, 2022
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1AMX
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1QC5
 | | I Domain from Integrin Alpha1-Beta1 | | 分子名称: | MAGNESIUM ION, PROTEIN (ALPHA1 BETA1 INTEGRIN) | | 著者 | Deivanayagam, C.C, Narayana, S.V. | | 登録日 | 1999-05-17 | | 公開日 | 2000-05-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM.
J.Biol.Chem., 274, 1999
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2F6A
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2F68
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5JQ6
 | | Crystal structure of ClfA in complex with the Fab fragment of Tefibazumab | | 分子名称: | Clumping factor A, Tefibazumab FAB FRAGMENT HEAVY CHAIN, Tefibazumab FAB FRAGMENT LIGHT CHAIN | | 著者 | Ganesh, V.K. | | 登録日 | 2016-05-04 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.
EBioMedicine, 13, 2016
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2Z1P
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3ASW
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3AT0
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7ZJQ
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