3BQK
 
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3BQI
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3BQL
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1T5E
 | | The structure of MexA | | 分子名称: | D-Glyceraldehyde, GLYCEROL, Multidrug resistance protein mexA | | 著者 | Higgins, M.K, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V. | | 登録日 | 2004-05-04 | | 公開日 | 2004-05-18 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the periplasmic component of a bacterial drug efflux pump
Proc.Natl.Acad.Sci.USA, 101, 2004
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1TQQ
 | | Structure of TolC in complex with hexamminecobalt | | 分子名称: | COBALT HEXAMMINE(III), Outer membrane protein tolC | | 著者 | Higgins, M.K, Eswaran, J, Edwards, P.C, Schertler, G.F, Hughes, C, Koronakis, V. | | 登録日 | 2004-06-18 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug effllux protein TolC
J.Mol.Biol., 342, 2004
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4E40
 | | The haptoglobin-hemoglobin receptor of Trypanosoma congolense | | 分子名称: | Putative uncharacterized protein | | 著者 | Higgins, M.K, Tkachenko, O, Brown, A, Reed, J, Carrington, M. | | 登録日 | 2012-03-11 | | 公開日 | 2013-01-16 | | 最終更新日 | 2013-02-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4V3E
 | | The CIDRa domain from IT4var07 PfEMP1 bound to endothelial protein C receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | | 著者 | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | | 登録日 | 2014-10-17 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
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4V3D
 | | The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | | 著者 | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | | 登録日 | 2014-10-17 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
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7ZXF
 | | Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1 | | 分子名称: | 10D8 heavy chain, 10D8 light chain, 85RF45.1 heavy chain, ... | | 著者 | Ko, K.T, Lennartz, F.L, Higgins, M.K. | | 登録日 | 2022-05-20 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.72 Å) | | 主引用文献 | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
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7ZWF
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7ZWM
 | | Pfs48/45 central and C-terminal domains bound to Fab fragments of monoclonal antibody 10D8 and 32F3 | | 分子名称: | 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ko, K.T, Lennartz, F.L, Higgins, M.K. | | 登録日 | 2022-05-19 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.69 Å) | | 主引用文献 | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
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7ZWI
 | | Pfs48/45 C-terminal domain bound to fab fragment of monoclonal antibody 32F3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 32F3 heavy chain, 32F3 light chain, ... | | 著者 | Ko, K.T, Lennartz, F.L, Higgins, M.K. | | 登録日 | 2022-05-19 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
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7ZXG
 | | Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8 | | 分子名称: | 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ko, K.T, Lennartz, F.L, Higgins, M.K. | | 登録日 | 2022-05-20 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
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8CDE
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8CDD
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8OVB
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8A44
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6RCV
 | | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | | 分子名称: | R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.582 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCO
 | | PfRH5-binding monoclonal antibody R5.004 | | 分子名称: | ACETATE ION, GLYCEROL, R5.004 heavy chain, ... | | 著者 | Alanine, D.G.W, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCU
 | | PfRH5 bound to monoclonal antibodies R5.004 and R5.016 | | 分子名称: | R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (4.005 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCQ
 | | PfRH5-binding monoclonal antibody R5.011 | | 分子名称: | ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... | | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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6RCS
 | | PfRH5-binding monoclonal antibody R5.016 | | 分子名称: | ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... | | 著者 | Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. | | 登録日 | 2019-04-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
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5HU6
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8PWX
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8PWV
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