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Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with Glyburide
分子名称:	1,2-ETHANEDIOL, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, CHLORIDE ION, ...
著者	Dranow, D.M, Hewitt, S.N, Abendroth, J, Structural Genomics Consortium (SGC)
登録日	2016-02-26
公開日	2016-11-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.45 Å)
主引用文献	Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infect Dis, 3, 2017

2KN9

Solution structure of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Seattle Structural Genomics Center for Infectious Disease target MytuD.01635.a
分子名称:	Rubredoxin, ZINC ION
著者	Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2009-08-20
公開日	2009-09-15
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 67, 2011

2KOK

Solution structure of an arsenate reductase (ArsC) related protein from Brucella melitensis. Seattle Structural Genomics Center for Infectious Disease target BrabA.00007.a.
分子名称:	arsenate reductase
著者	Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2009-09-23
公開日	2009-10-13
最終更新日	2024-05-08
実験手法	SOLUTION NMR
主引用文献	Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis. Acta Crystallogr.,Sect.F, 67, 2011

4Q15

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with Halofuginone and AMPPNP in space group P212121 at 2.35 A
分子名称:	1,2-ETHANEDIOL, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, ...
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2014-04-02
公開日	2016-04-20
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. Acs Infect Dis., 3, 2017

4NCX

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum 3D7
分子名称:	1,2-ETHANEDIOL, CHLORIDE ION, Proline--tRNA ligase
著者	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2013-10-25
公開日	2014-10-29
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. Acs Infect Dis., 3, 2017

3SDS

Crystal structure of a mitochondrial ornithine carbamoyltransferase from Coccidioides immitis
分子名称:	CHLORIDE ION, Ornithine carbamoyltransferase, mitochondrial
著者	Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-06-09
公開日	2011-06-22
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallogr.,Sect.F, 67, 2011

3TL6

Crystal structure of purine nucleoside phosphorylase from Entamoeba histolytica
分子名称:	Purine nucleoside phosphorylase, SULFATE ION
著者	Edwards, T.E, Clifton, M.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-08-29
公開日	2011-09-07
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallogr.,Sect.F, 67, 2011

3U40

Crystal structure of a purine nucleoside phosphorylase from Entamoeba histolytica bound to adenosine
分子名称:	ADENOSINE, NITRATE ION, PHOSPHATE ION, ...
著者	Edwards, T.E, Gardberg, A.S, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-10-06
公開日	2011-10-19
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallogr.,Sect.F, 67, 2011

6UHW

Solution structure of an organic hydroperoxide resistance protein from Burkholderia pseudomallei. Seattle Structural Genomics Center for Infectious Disease target BupsA.00074.a.
分子名称:	Organic hydroperoxide resistance protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2019-09-29
公開日	2019-10-16
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Backbone and side chain (1)H, (13)C, and (15)N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei. Biomol.Nmr Assign., 3, 2009

3KHP

Crystal structure of a possible dehydrogenase from Mycobacterium tuberculosis at 2.3A resolution
分子名称:	CHLORIDE ION, L(+)-TARTARIC ACID, MaoC family protein
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2009-10-30
公開日	2009-12-01
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

3LLS

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Mycobacterium tuberculosis
分子名称:	1,2-ETHANEDIOL, 3-ketoacyl-(Acyl-carrier-protein) reductase, SULFATE ION
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2010-01-29
公開日	2010-02-16
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

2KZ0

Solution structure of a BolA protein (ECH_0303) from Ehrlichia chaffeensis. Seattle Structural Genomics Center for Infectious Disease target EhchA.10365.a
分子名称:	BolA family protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2010-06-10
公開日	2010-06-23
最終更新日	2024-05-22
実験手法	SOLUTION NMR
主引用文献	Structural characterization of a BolA protein (ECH_0303) from Ehrlichia chaffeensis, the agent responsible for human monocytotropic ehrlichiosis. To be Published

2LGO

Solution NMR structure of a FKBP-type peptidyl-prolyl cis-trans isomerase from Giardia lamblia, Seattle Structural Genomics Center for Infectious Disease target GilaA.00840.a
分子名称:	FKBP
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-07-29
公開日	2011-08-17
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of a putative FKBP-type peptidyl-propyl cis-trans isomerase from Giardia lamblia. J.Biomol.Nmr, 57, 2013

3TL3

Structure of a short-chain type dehydrogenase/reductase from Mycobacterium ulcerans
分子名称:	SODIUM ION, Short-chain type dehydrogenase/reductase
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-08-29
公開日	2011-09-07
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

3TX2

Structure of a Probable 6-phosphogluconolactonase from Mycobacterium abscessus
分子名称:	BENZOIC ACID, GLYCEROL, Probable 6-phosphogluconolactonase, ...
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-09-22
公開日	2011-10-05
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

3TRR

Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
分子名称:	1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-09-09
公開日	2011-09-21
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.09 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

3TZQ

Crystal structure of a short-chain type dehydrogenase/reductase from Mycobacterium marinum
分子名称:	1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2011-09-27
公開日	2011-10-05
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4F3W

Crystal structure of cytidine deaminase Cdd from Mycobacterium marinum
分子名称:	Cytidine deaminase Cdd, ZINC ION
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2012-05-09
公開日	2012-05-23
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4F47

The Structure of Enoyl-CoA hydratase EchA19 from Mycobacterium marinum
分子名称:	Enoyl-CoA hydratase EchA19
著者	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2012-05-10
公開日	2012-05-30
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4FFC

Crystal structure of a 4-aminobutyrate aminotransferase (GabT) from Mycobacterium abscessus
分子名称:	1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase (GabT)
著者	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2012-05-31
公開日	2012-06-13
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

2LPD

Solution structure of a MbtH-like protein from Burkholderia pseudomallei, the etiological agent responsible for melioidosis, Seattle Structural Genomics Center for Infectious Disease target BupsA.13472.b
分子名称:	Uncharacterized protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2012-02-10
公開日	2012-02-22
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of a MbtH-like protein from Burkholderia pseudomallei, the etiological agent responsible for melioidosis To be Published

2LXF

Solution NMR structure of a potential acylphosphatase from Giardia lamblia, Seattle Structural Genomics Center for Infectious Disease target GilaA.01396.a
分子名称:	Uncharacterized protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2012-08-20
公開日	2012-09-12
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of an acylphosphatase from Giardia lamblia, the etiological agent responsible for giardiasis To be Published

2N6G

Solution structure of an MbtH-like protein from Mycobacterium avium, Seattle Structural Genomics Center for Infectious Disease target MyavA.01649.c
分子名称:	MbtH-like protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2015-08-20
公開日	2015-12-30
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of a MbtH-like protein from Mycobacterium avium. To be Published

2MU0

Solution structure of a putative arsenate reductase from Brucella melitensis. Seattle Structural Genomics Center for Infectious Disease target BrabA.00073.a
分子名称:	Arsenate reductase
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2014-09-02
公開日	2014-09-17
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution NMR structure of an arsenate reductase from Brucella melitensis. To be Published

2MYY

Solution structure of an MbtH-like protein from Mycobacterium marinum, Seattle Structural Genomics Center for Infectious Disease target MymaA.01649.c
分子名称:	Conserved hypothetical MbtH-like protein
著者	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日	2015-02-02
公開日	2015-04-01
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of an MbtH-like protein from Mycobacterium marinum, Seattle Structural Genomics Center for Infectious Disease target MymaA.01649.c To be Published

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