1ZVI
 
 | | Rat Neuronal Nitric Oxide Synthase Oxygenase Domain | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric-oxide synthase, brain, ... | | 著者 | Matter, H, Kumar, H.S, Fedorov, R, Frey, A, Kotsonis, P, Hartmann, E, Frohlich, L.G, Reif, A, Pfleiderer, W, Scheurer, P, Ghosh, D.K, Schlichting, I, Schmidt, H.H. | | 登録日 | 2005-06-02 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
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1ZVL
 | | Rat Neuronal Nitric Oxide Synthase Oxygenase Domain complexed with natural substrate L-Arg. | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric-oxide synthase, ... | | 著者 | Matter, H, Kumar, H.S, Fedorov, R, Frey, A, Kotsonis, P, Hartmann, E, Frohlich, L.G, Reif, A, Pfleiderer, W, Scheurer, P, Ghosh, D.K, Schlichting, I, Schmidt, H.H. | | 登録日 | 2005-06-02 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases.
J.Med.Chem., 48, 2005
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9GBH
 | | CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND1 | | 分子名称: | 2-(3,4-dimethoxyphenyl)-3,5-bis(oxidanylidene)-4-[[3-(trifluoromethyl)phenyl]methyl]-1,2,4-triazine-6-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... | | 著者 | Schaefer, M, Fuerstner, C, Ackerstaff, J, Meier, H, Straub, A, Mittendorf, J, Schamberger, J, Boerngen, K, Joerissen, H, Zubow, D, Zimmermann, K, Tersteegen, A, Geiss, V, Hartmann, E, Albrecht-Kuepper, B, Dorleans-Juste, P, Lapointe, C, Vincent, L, Heitmeier, S, Tinel, H. | | 登録日 | 2024-07-31 | | 公開日 | 2024-11-27 | | 最終更新日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (2.375 Å) | | 主引用文献 | Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution.
J.Med.Chem., 68, 2025
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4HU4
 | | Crystal structure of EAL domain of the E. coli DosP - dimeric form | | 分子名称: | Oxygen sensor protein DosP | | 著者 | Tarnawski, M, Barends, T.R.M, Hartmann, E, Schlichting, I. | | 登録日 | 2012-11-02 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
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4HU3
 | | Crystal structure of EAL domain of the E. coli DosP - monomeric form | | 分子名称: | Oxygen sensor protein DosP | | 著者 | Tarnawski, M, Barends, T.R.M, Hartmann, E, Schlichting, I. | | 登録日 | 2012-11-02 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | | 主引用文献 | Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor.
Acta Crystallogr.,Sect.D, 69, 2013
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7AV4
 | | Dark state structure of the C432S mutant of Fatty Acid Photodecarboxylase (FAP) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid photodecarboxylase, chloroplastic, ... | | 著者 | Schlichting, I, Hartmann, E, Arnoux, P, Sorigue, D, Beisson, F. | | 登録日 | 2020-11-04 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.936 Å) | | 主引用文献 | Mechanism and dynamics of fatty acid photodecarboxylase.
Science, 372, 2021
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1RD5
 | | Crystal structure of Tryptophan synthase alpha chain homolog BX1: a member of the chemical plant defense system | | 分子名称: | MALONIC ACID, Tryptophan synthase alpha chain, chloroplast | | 著者 | Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I. | | 登録日 | 2003-11-05 | | 公開日 | 2004-12-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
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1QWC
 | | Rat neuronal nitric oxide synthase oxygenase domain in complex with W1400 inhibitor. | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, Nitric-oxide synthase, ... | | 著者 | Fedorov, R, Hartmann, E, Ghosh, D.K, Schlichting, I. | | 登録日 | 2003-09-02 | | 公開日 | 2003-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
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1QW4
 | | Crystal Structure of Murine Inducible Nitric Oxide Synthase Oxygenase Domain in complex with N-omega-propyl-L-arginine. | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, N-OMEGA-PROPYL-L-ARGININE, Nitric oxide synthase, ... | | 著者 | Fedorov, R, Hartmann, E, Ghosh, D.K, Schlichting, I. | | 登録日 | 2003-08-31 | | 公開日 | 2003-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
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1N9L
 | | Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in the dark state. | | 分子名称: | FLAVIN MONONUCLEOTIDE, SULFATE ION, putative blue light receptor | | 著者 | Fedorov, R, Schlichting, I, Hartmann, E, Domratcheva, T, Fuhrmann, M, Hegemann, P. | | 登録日 | 2002-11-25 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
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1N9O
 | | Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in illuminated state. Composite data set. | | 分子名称: | FLAVIN MONONUCLEOTIDE, SULFATE ION, putative blue light receptor | | 著者 | Fedorov, R, Schlichting, I, Hartmann, E, Domratcheva, T, Fuhrmann, M, Hegemann, P. | | 登録日 | 2002-11-25 | | 公開日 | 2003-06-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
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1N9N
 | | Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in illuminated state. Data set of a single crystal. | | 分子名称: | FLAVIN MONONUCLEOTIDE, putative blue light receptor | | 著者 | Fedorov, R, Schlichting, I, Hartmann, E, Domratcheva, T, Fuhrmann, M, Hegemann, P. | | 登録日 | 2002-11-25 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii.
Biophys.J., 84, 2003
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1QW5
 | | Murine inducible nitric oxide synthase oxygenase domain in complex with W1400 inhibitor. | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, Nitric oxide synthase, ... | | 著者 | Fedorov, R, Hartmann, E, Ghosh, D.K, Schlichting, I. | | 登録日 | 2003-08-31 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
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5M2A
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-10-12 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5M27
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-10-12 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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1RH5
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-13 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel
Nature, 427, 2004
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5MBD
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBJ
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBE
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBH
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBG
 | | Structure of a bacterial light-regulated adenylyl cyclase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, IODIDE ION | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBC
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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5MBB
 | | Structure of a bacterial light-regulated adenylyl cylcase | | 分子名称: | Beta subunit of photoactivated adenylyl cyclase, FLAVIN MONONUCLEOTIDE | | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase.
J. Mol. Biol., 429, 2017
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1TJR
 | | Crystal structure of wild-type BX1 complexed with a sulfate ion | | 分子名称: | BX1, SULFATE ION | | 著者 | Kulik, V, Hartmann, E, Weyand, M, Frey, M, Gierl, A, Niks, D, Dunn, M.F, Schlichting, I. | | 登録日 | 2004-06-07 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | On the structural basis of the catalytic mechanism and the regulation of the alpha subunit of tryptophan synthase from Salmonella typhimurium and BX1 from maize, two evolutionarily related enzymes.
J.Mol.Biol., 352, 2005
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1QW6
 | | Rat neuronal nitric oxide synthase oxygenase domain in complex with N-omega-propyl-L-Arg. | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, N-OMEGA-PROPYL-L-ARGININE, Nitric-oxide synthase, ... | | 著者 | Fedorov, R, Hartmann, E, Ghosh, D.K, Schlichting, I. | | 登録日 | 2003-09-01 | | 公開日 | 2003-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms.
J.Biol.Chem., 278, 2003
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