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Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations
分子名称:	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, SODIUM ION
著者	Hajicek, N, Sondek, J.
登録日	2019-06-13
公開日	2020-01-08
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.46 Å)
主引用文献	Structural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated mutations. Elife, 8, 2019

Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
分子名称:	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
著者	Hajicek, N, Sondek, J.
登録日	2013-04-11
公開日	2013-06-26
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes. Biochemistry, 52, 2013

Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
分子名称:	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, short peptide
著者	Sondek, J, Hajicek, N.
登録日	2013-04-11
公開日	2013-06-26
最終更新日	2014-01-22
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Autoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes. Biochemistry, 52, 2013

Crystal structure of p115RhoGEF RGS domain in complex with G alpha 13
分子名称:	GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, Guanine nucleotide-binding protein subunit alpha-13, ...
著者	Kukimoto-Niino, M, Mishima, C, Shirouzu, M, Kozasa, T, Yokoyama, S.
登録日	2009-11-30
公開日	2010-12-29
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex. J.Biol.Chem., 286, 2011