6RNK
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![BU of 6rnk by Molmil](/molmil-images/mine/6rnk) | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist NF-56-EJ40. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[[3-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]carbonylamino]phenyl]ethanoic acid, GLYCEROL, ... | 著者 | Haffke, M, Jaakola, V.-P. | 登録日 | 2019-05-08 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural basis of species-selective antagonist binding to the succinate receptor. Nature, 574, 2019
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6IBB
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![BU of 6ibb by Molmil](/molmil-images/mine/6ibb) | Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a nanobody | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{S},5~{R})-hexane-2,5-diol, CHOLESTEROL, ... | 著者 | Haffke, M, Jaakola, V.-P. | 登録日 | 2018-11-29 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis of species-selective antagonist binding to the succinate receptor. Nature, 574, 2019
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3NHB
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![BU of 3nhb by Molmil](/molmil-images/mine/3nhb) | Nucleotide Binding Domain of Human ABCB6 (ADP bound structure) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, mitochondrial, ... | 著者 | Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W. | 登録日 | 2010-06-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides. Acta Crystallogr.,Sect.D, 66, 2010
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3NHA
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![BU of 3nha by Molmil](/molmil-images/mine/3nha) | Nucleotide Binding Domain of Human ABCB6 (ADP Mg bound structure) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 6, mitochondrial, ... | 著者 | Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W. | 登録日 | 2010-06-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides. Acta Crystallogr.,Sect.D, 66, 2010
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3NH6
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![BU of 3nh6 by Molmil](/molmil-images/mine/3nh6) | Nucleotide Binding Domain of human ABCB6 (apo structure) | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial, BETA-MERCAPTOETHANOL | 著者 | Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W. | 登録日 | 2010-06-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides. Acta Crystallogr.,Sect.D, 66, 2010
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3NH9
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![BU of 3nh9 by Molmil](/molmil-images/mine/3nh9) | Nucleotide Binding Domain of Human ABCB6 (ATP bound structure) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, mitochondrial, ... | 著者 | Haffke, M, Menzel, A, Carius, Y, Jahn, D, Heinz, D.W. | 登録日 | 2010-06-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides. Acta Crystallogr.,Sect.D, 66, 2010
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6F3T
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![BU of 6f3t by Molmil](/molmil-images/mine/6f3t) | Crystal structure of the human TAF5-TAF6-TAF9 complex | 分子名称: | CHLORIDE ION, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, ... | 著者 | Haffke, M, Berger, I. | 登録日 | 2017-11-28 | 公開日 | 2018-12-05 | 最終更新日 | 2018-12-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly. Nat. Struct. Mol. Biol., 25, 2018
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6Z10
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![BU of 6z10 by Molmil](/molmil-images/mine/6z10) | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[[3-[4-chloranyl-2-fluoranyl-5-[(3~{R})-piperidin-3-yl]oxy-phenyl]-2-fluoranyl-phenyl]carbonylamino]-5-fluoranyl-phenyl]ethanoic acid, CHLORIDE ION, ... | 著者 | Haffke, M, Villard, F. | 登録日 | 2020-05-11 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.269 Å) | 主引用文献 | Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. J.Med.Chem., 63, 2020
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5HM1
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![BU of 5hm1 by Molmil](/molmil-images/mine/5hm1) | |
3ONM
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![BU of 3onm by Molmil](/molmil-images/mine/3onm) | Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis | 分子名称: | Transcriptional regulator LrhA | 著者 | Quade, N, Diekmann, M, Haffke, M, Heroven, A.K, Dersch, P, Heinz, D.W. | 登録日 | 2010-08-30 | 公開日 | 2011-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis. Acta Crystallogr.,Sect.D, 67, 2011
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4WV6
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![BU of 4wv6 by Molmil](/molmil-images/mine/4wv6) | |
4WV4
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![BU of 4wv4 by Molmil](/molmil-images/mine/4wv4) | Heterodimer of TAF8/TAF10 | 分子名称: | CHLORIDE ION, GLYCEROL, Transcription initiation factor TFIID subunit 10, ... | 著者 | Trowitzsch, S. | 登録日 | 2014-11-04 | 公開日 | 2015-01-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.909 Å) | 主引用文献 | Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
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