2U2F
| SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN OF HU2AF65 | 分子名称: | PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT) | 著者 | Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 1999-05-26 | 公開日 | 1999-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)). EMBO J., 18, 1999
|
|
1JMT
| X-ray Structure of a Core U2AF65/U2AF35 Heterodimer | 分子名称: | HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT | 著者 | Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K. | 登録日 | 2001-07-19 | 公開日 | 2001-09-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. Cell(Cambridge,Mass.), 106, 2001
|
|
1T5I
| |
1U2F
| SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN OF HU2AF65 | 分子名称: | PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT) | 著者 | Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 1999-05-26 | 公開日 | 1999-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)). EMBO J., 18, 1999
|
|
4OZ0
| |
2G4B
| |
2YH1
| Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT | 著者 | Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M. | 登録日 | 2011-04-26 | 公開日 | 2011-07-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af Nature, 475, 2011
|
|
3VAG
| Structure of U2AF65 variant with BrU3C2 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAH
| Structure of U2AF65 variant with BrU3C4 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(P*UP*UP*(BRU)P*CP*UP*UP*U)-3', GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAL
| Structure of U2AF65 variant with BrU5C1 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ... | 著者 | Jenkins, J.L, Frato, K.H, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAK
| Structure of U2AF65 variant with BrU5 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2017-08-16 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAF
| Structure of U2AF65 variant with BrU3 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAM
| Structure of U2AF65 variant with BrU5C2 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAJ
| Structure of U2AF65 variant with BrU5C6 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*CP*U)-3'), GLYCEROL, ... | 著者 | Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
3VAI
| Structure of U2AF65 variant with BrU3C5 DNA | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', GLYCEROL, ... | 著者 | Jenkins, J.L, Frato, K.H, Kielkopf, C.L. | 登録日 | 2011-12-29 | 公開日 | 2013-02-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
|
|
5EV1
| Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2015-11-19 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.037 Å) | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
|
|
5EV2
| Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2015-11-19 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
|
|
5EV3
| |
5EV4
| |
8V4X
| Structure of MALT1 in complex with an allosteric inhibitor | 分子名称: | Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea | 著者 | Judge, R.A, Pappano, W.N. | 登録日 | 2023-11-29 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | 主引用文献 | Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma. Mol.Cancer Ther., 23, 2024
|
|
4FXW
| Structure of phosphorylated SF1 complex with U2AF65-UHM domain | 分子名称: | SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit | 著者 | Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L. | 登録日 | 2012-07-03 | 公開日 | 2013-01-16 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
|
|
4FXX
| Structure of SF1 coiled-coil domain | 分子名称: | IMIDAZOLE, MALONATE ION, Splicing factor 1 | 著者 | Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. | 登録日 | 2012-07-03 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4801 Å) | 主引用文献 | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
|
|
1BHI
| STRUCTURE OF TRANSACTIVATION DOMAIN OF CRE-BP1/ATF-2, NMR, 20 STRUCTURES | 分子名称: | CRE-BP1 | 著者 | Nagadoi, A, Nakazawa, K, Uda, H, Maekawa, T, Ishii, S, Nishimura, Y. | 登録日 | 1998-06-09 | 公開日 | 1999-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the transactivation domain of ATF-2 comprising a zinc finger-like subdomain and a flexible subdomain. J.Mol.Biol., 287, 1999
|
|
4OZ1
| |
1T6N
| |