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1Z3N
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BU of 1z3n by Molmil
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase, {3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID
著者Van Zandt, M.C, Jones, M.L, Gunn, D.E, Geraci, L.S, Jones, J.H, Sawicki, D.R, Sredy, J, Jacot, J.L, Dicioccio, A.T, Petrova, T, Mitschler, A, Podjarny, A.D.
登録日2005-03-14
公開日2006-03-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications
J.Med.Chem., 48, 2005
4GCA
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BU of 4gca by Molmil
Complex of Aldose Reductase with inhibitor IDD 1219
分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2,6-dimethyl-5-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]pyridin-3-yl}acetic acid
著者Podjarny, A.D, Van Zandt, M, Geraci, L.S.
登録日2012-07-30
公開日2013-07-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Complex of Aldose Reductase with inhibitor IDD 1219
TO BE PUBLISHED

227111

件を2024-11-06に公開中

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