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4GCA

Complex of Aldose Reductase with inhibitor IDD 1219

Summary for 4GCA
Entry DOI10.2210/pdb4gca/pdb
Related1US0
DescriptorAldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2,6-dimethyl-5-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]pyridin-3-yl}acetic acid, ... (4 entities in total)
Functional Keywordsoxidoreductase, tim barrel, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15121
Total number of polymer chains1
Total formula weight36876.91
Authors
Podjarny, A.D.,Van Zandt, M.,Geraci, L.S. (deposition date: 2012-07-30, release date: 2013-07-31, Last modification date: 2024-02-28)
Primary citationPodjarny, A.D.,Van Zandt, M.,Geraci, L.S.
Complex of Aldose Reductase with inhibitor IDD 1219
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (0.9 Å)
Structure validation

229183

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