6NAN
| NMR structure determination of Ixolaris and Factor X interaction reveals a noncanonical mechanism of Kunitz inhibition | 分子名称: | Ixolaris | 著者 | De Paula, V.S, Sgourakis, N.G, Francischetti, I.M.B, Almeida, F.C.L, Monteiro, R.Q, Valente, A.P. | 登録日 | 2018-12-06 | 公開日 | 2019-06-12 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition. Blood, 134, 2019
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8ENU
| Structure of the C3bB proconvertase in complex with lufaxin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | 著者 | Andersen, J.F, Lei, H. | 登録日 | 2022-09-30 | 公開日 | 2023-08-09 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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8EO2
| Lufaxin a bifunctional inhibitor of complement and coagulation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | 著者 | Andersen, J.F, Strayer, E.C. | 登録日 | 2022-10-01 | 公開日 | 2023-08-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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8EOK
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7TVY
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7U1N
| Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-ETHOXYETHANOL, ... | 著者 | Alvarenga, P.H, Gittis, A.G, Garboczi, D.N, Andersen, J.F. | 登録日 | 2022-02-21 | 公開日 | 2022-05-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes. Insect Biochem.Mol.Biol., 146, 2022
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7TVC
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7TX8
| Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Long form D7 salivary protein, SEROTONIN | 著者 | Andersen, J.F, Alvarenga, P.H. | 登録日 | 2022-02-08 | 公開日 | 2022-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes. Insect Biochem.Mol.Biol., 146, 2022
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