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5E7J
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BU of 5e7j by Molmil
Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMP
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X
著者Floor, S.N, Condon, K.J, Doudna, J.A.
登録日2015-10-12
公開日2015-12-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.
J.Biol.Chem., 291, 2016
5E7M
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BU of 5e7m by Molmil
Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMPPNP
分子名称: ATP-dependent RNA helicase DDX3X, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Floor, S.N, Condon, K.J, Doudna, J.A.
登録日2015-10-12
公開日2015-12-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.
J.Biol.Chem., 291, 2016
5E7I
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BU of 5e7i by Molmil
Crystal structure of the active catalytic core of the human DEAD-box protein DDX3
分子名称: ATP-dependent RNA helicase DDX3X
著者Floor, S.N, Condon, K.J, Doudna, J.A.
登録日2015-10-12
公開日2015-12-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.
J.Biol.Chem., 291, 2016
4KG4
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BU of 4kg4 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain (E198Q mutation)
分子名称: mRNA-decapping enzyme subunit 2
著者Aglietti, R.A, Floor, S.N, Gross, J.D.
登録日2013-04-28
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4K6E
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BU of 4k6e by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg
分子名称: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
著者Aglietti, R.A, Floor, S.N, Gross, J.D.
登録日2013-04-15
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4KG3
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BU of 4kg3 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg (E153Q mutation)
分子名称: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
著者Aglietti, R.A, Floor, S.N, Gross, J.D.
登録日2013-04-28
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
8JHU
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BU of 8jhu by Molmil
Legionella effector protein SidI
分子名称: Legionella pneumophila effector protein SidI
著者Wang, L, Subramanian, A, Mukherjee, S, Walter, P.
登録日2023-05-25
公開日2023-08-30
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.
Nat.Cell Biol., 25, 2023
2JVB
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BU of 2jvb by Molmil
Solution Structure of Catalytic Domain of yDcp2
分子名称: mRNA-decapping enzyme subunit 2
著者Deshmukh, M, Gross, J.
登録日2007-09-16
公開日2008-03-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2.
Mol.Cell, 29, 2008
5ZC9
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BU of 5zc9 by Molmil
Crystal structure of the human eIF4A1-ATP analog-RocA-polypurine RNA complex
分子名称: (1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ...
著者Iwasaki, W, Takahashi, M, Sakamoto, A, Iwasaki, S, Ito, T.
登録日2018-02-16
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Mol. Cell, 73, 2019

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