4W61
 
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6TBB
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6TBC
 | | Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B | | 分子名称: | (2~{E},5~{R},10~{E},12~{E},15~{S},19~{R})-20-[[(2~{R},3~{R})-3-aminocarbonyloxy-2-methyl-butanoyl]amino]-3,5,15-trimethyl-7-methylidene-19-oxidanyl-17-oxidanylidene-icosa-2,10,12-trienoic acid, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Fage, C.D, Masschelein, J. | | 登録日 | 2019-11-01 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6TA8
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4TN0
 | | Crystal Structure of the C-terminal Periplasmic Domain of Phosphoethanolamine Transferase EptC from Campylobacter jejuni | | 分子名称: | UPF0141 protein yjdB, ZINC ION | | 著者 | Fage, C.D, Brown, D, Boll, J.M, Keatinge-Clay, A.T, Trent, M.S. | | 登録日 | 2014-06-02 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni.
Acta Crystallogr.,Sect.D, 70, 2014
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4PNE
 | | Crystal Structure of the [4+2]-Cyclase SpnF | | 分子名称: | MALONATE ION, Methyltransferase-like protein, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Fage, C.D, Isiorho, E.A, Liu, Y.-N, Liu, H.-W, Keatinge-Clay, A.T. | | 登録日 | 2014-05-23 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition.
Nat.Chem.Biol., 11, 2015
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8AW0
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8AVZ
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5JRK
 | | Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (SeMet-derived) | | 分子名称: | Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein, beta-D-glucopyranose | | 著者 | Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. | | 登録日 | 2016-05-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew.Chem.Int.Ed.Engl., 55, 2016
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5JRL
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5JQF
 | | Crystal structure of the lasso peptide Sphingopyxin I (SpI) | | 分子名称: | Sphingopyxin I | | 著者 | Fage, C.D, Hegemann, J.D, Harms, K, Bange, G, Marahiel, M.A. | | 登録日 | 2016-05-04 | | 公開日 | 2016-09-14 | | 最終更新日 | 2021-06-16 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew. Chem. Int. Ed. Engl., 55, 2016
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5D9E
 | | Crystal Structure of the Proline-rich Lasso Peptide Caulosegnin II | | 分子名称: | CHLORIDE ION, Caulosegnin II | | 著者 | Fage, C.D, Hegemann, J.D, Harms, K, Marahiel, M.A. | | 登録日 | 2015-08-18 | | 公開日 | 2016-02-17 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.859 Å) | | 主引用文献 | The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II.
Mol Biosyst, 12, 2016
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4OXI
 | | Crystal structure of Vibrio cholerae adenylation domain AlmE in complex with glycyl-adenosine-5'-phosphate | | 分子名称: | Enterobactin synthetase component F-related protein, GLYCYL-ADENOSINE-5'-PHOSPHATE | | 著者 | Fage, C.D, Henderson, J.C, Keatinge-Clay, A.T, Trent, M.S. | | 登録日 | 2014-02-05 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | | 主引用文献 | Antimicrobial peptide resistance of Vibrio cholerae results from an LPS modification pathway related to nonribosomal peptide synthetases.
Acs Chem.Biol., 9, 2014
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8AQR
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8AQQ
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5OQZ
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5DED
 | | Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to its product pppGpp | | 分子名称: | GTP pyrophosphokinase YjbM, MAGNESIUM ION, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | | 著者 | Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G. | | 登録日 | 2015-08-25 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.942 Å) | | 主引用文献 | Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5F2V
 | | Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to AMPCPP | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GTP pyrophosphokinase YjbM, MAGNESIUM ION | | 著者 | Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G. | | 登録日 | 2015-12-02 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5T3E
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5DEC
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4IMP
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5J8Q
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