6GLU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glu by Molmil](/molmil-images/mine/6glu) | Crystal structure of hMTH1 D120N in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | hMTH1 D120N in complex with LW14 To Be Published
|
|
6GLF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glf by Molmil](/molmil-images/mine/6glf) | |
6GLL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gll by Molmil](/molmil-images/mine/6gll) | Crystal structure of hMTH1 N33A in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.395 Å) | 主引用文献 | hMTH1 N33A in complex with LW14 To Be Published
|
|
6GLE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gle by Molmil](/molmil-images/mine/6gle) | Crystal structure of hMTH1 in complex with TH scaffold 1 in the presence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | 主引用文献 | hMTH1 in complex with TH scaffold 1 To Be Published
|
|
6GLK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glk by Molmil](/molmil-images/mine/6glk) | |
6GLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glr by Molmil](/molmil-images/mine/6glr) | Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the presence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 N33G in complex with TH scaffold 1 To Be Published
|
|
6GLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glg by Molmil](/molmil-images/mine/6glg) | Crystal structure of hMTH1 F27A in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.313 Å) | 主引用文献 | hMTH1 F27A in complex with LW14 To Be Published
|
|
6GLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glm by Molmil](/molmil-images/mine/6glm) | Crystal structure of hMTH1 N33A in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | hMTH1 N33A in complex with LW14 To Be Published
|
|
6GLS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gls by Molmil](/molmil-images/mine/6gls) | Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | hMTH1 N33G in complex with TH scaffold 1. To Be Published
|
|
6GLQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glq by Molmil](/molmil-images/mine/6glq) | Crystal structure of hMTH1 N33G in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 N33G in complex with LW14. To Be Published
|
|
6GLJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glj by Molmil](/molmil-images/mine/6glj) | Crystal structure of hMTH1 F27A in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.301 Å) | 主引用文献 | hMTH1 F27A in complex with TH scaffold 1. To Be Published
|
|
6GLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glo by Molmil](/molmil-images/mine/6glo) | |
6GLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glh by Molmil](/molmil-images/mine/6glh) | Crystal structure of hMTH1 F27A in complex with LW14 in the absence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | 主引用文献 | hMTH1 F27A in complex with LW14 To Be Published
|
|
6GLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glp by Molmil](/molmil-images/mine/6glp) | Crystal structure of hMTH1 N33G in complex with LW14 in the presence of acetate | 分子名称: | 1~{H}-imidazo[4,5-b]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | hMTH1 N33G in complex with LW14 To Be Published
|
|
6GLI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gli by Molmil](/molmil-images/mine/6gli) | |
6GLN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gln by Molmil](/molmil-images/mine/6gln) | Crystal structure of hMTH1 N33A in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | hMTH1 N33A in complex with TH scaffold 1 To Be Published
|
|
6GLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glv by Molmil](/molmil-images/mine/6glv) | Crystal structure of hMTH1 D120N in complex with TH scaffold 1 in the absence of acetate | 分子名称: | 4-phenylpyrimidin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION | 著者 | Eberle, S.A, Wiedmer, L, Sledz, P, Caflisch, A. | 登録日 | 2018-05-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | hMTH1 D120N in complex with TH scaffold 1 To Be Published
|
|
6GLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6glt by Molmil](/molmil-images/mine/6glt) | |
7B6W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b6w by Molmil](/molmil-images/mine/7b6w) | Crystal structure of the human alpha1B adrenergic receptor in complex with inverse agonist (+)-cyclazosin | 分子名称: | Alpha-1B adrenergic receptor,alpha1B adrenergic receptor,Alpha-1B adrenergic receptor,alpha1B adrenergic receptor,Alpha-1B adrenergic receptor,alpha1B adrenergic receptor,Alpha-1B adrenergic receptor,alpha1B adrenergic receptor, [(4~{a}~{R},8~{a}~{S})-4-(4-azanyl-6,7-dimethoxy-quinazolin-2-yl)-2,3,4~{a},5,6,7,8,8~{a}-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone | 著者 | Deluigi, M, Morstein, L, Hilge, M, Schuster, M, Merklinger, L, Klipp, A, Scott, D.J, Plueckthun, A. | 登録日 | 2020-12-08 | 公開日 | 2022-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.873 Å) | 主引用文献 | Crystal structure of the alpha 1B -adrenergic receptor reveals molecular determinants of selective ligand recognition. Nat Commun, 13, 2022
|
|
7SK6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk6 by Molmil](/molmil-images/mine/7sk6) | Cryo-EM structure of human ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ and an intracellular Fab | 分子名称: | Atypical chemokine receptor 3, CID24 Fab heavy chain, CID24 Fab light chain, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk4 by Molmil](/molmil-images/mine/7sk4) | Cryo-EM structure of ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ, an intracellular Fab, and an extracellular Fab | 分子名称: | Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk9 by Molmil](/molmil-images/mine/7sk9) | Cryo-EM structure of human ACKR3 in complex with a small molecule partial agonist CCX662, and an intracellular Fab | 分子名称: | (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk3 by Molmil](/molmil-images/mine/7sk3) | Cryo-EM structure of ACKR3 in complex with CXCL12, an intracellular Fab, and an extracellular Fab | 分子名称: | Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk8 by Molmil](/molmil-images/mine/7sk8) | Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, an extracellular Fab, and an intracellular Fab | 分子名称: | (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|
7SK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sk5 by Molmil](/molmil-images/mine/7sk5) | Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab | 分子名称: | Anti-Fab nanobody, Atypical chemokine receptor 3, CHOLESTEROL, ... | 著者 | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | 登録日 | 2021-10-19 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
|
|