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1ITG
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BU of 1itg by Molmil
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HIV-1 INTEGRASE: SIMILARITY TO OTHER POLYNUCLEOTIDYL TRANSFERASES
分子名称: CACODYLATE ION, HIV-1 INTEGRASE
著者Dyda, F, Hickman, A.B, Jenkins, T.M, Engelman, A, Craigie, R, Davies, D.R.
登録日1994-11-21
公開日1995-05-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.
Science, 266, 1994
9AZ7
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BU of 9az7 by Molmil
Chloride Sites in Photoactive Yellow Protein
分子名称: 4'-HYDROXYCINNAMIC ACID, CHLORIDE ION, Photoactive yellow protein
著者Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
登録日2024-03-10
公開日2024-03-20
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
9AZ9
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BU of 9az9 by Molmil
Chloride Sites in Photoactive Yellow Protein (Chloride-Free Reference Structure)
分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
著者Dyda, F, Schotte, F, Anfinrud, P, Cho, H.S.
登録日2024-03-10
公開日2024-03-20
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Watching a signaling protein function: What has been learned over four decades of time-resolved studies of photoactive yellow protein.
Struct Dyn., 11, 2024
1PYD
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BU of 1pyd by Molmil
CATALYTIC CENTERS IN THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE AT 2.4 ANGSTROMS RESOLUTION
分子名称: MAGNESIUM ION, PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE
著者Furey, W, Dyda, F.
登録日1993-03-23
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution.
Biochemistry, 32, 1993
6DX0
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BU of 6dx0 by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA
分子名称: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
著者Dyda, F, Voth, A.R, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWW
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BU of 6dww by Molmil
Hermes transposase deletion dimer complex with (A/T) DNA and Mn2+
分子名称: DNA (25-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), ...
著者Dyda, F, Voth, A.R, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6DWY
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BU of 6dwy by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA and Ca2+
分子名称: CALCIUM ION, DNA (26-MER), DNA (5'-D(*AP*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
6OPM
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BU of 6opm by Molmil
Casposase bound to integration product
分子名称: CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ...
著者Dyda, F, Hickman, A.B, Kailasan, S.
登録日2019-04-25
公開日2020-02-12
最終更新日2020-08-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
6B67
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BU of 6b67 by Molmil
Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA)
分子名称: CALCIUM ION, Protein phosphatase 1A, cyclic peptide c(MpSIpYVA)
著者Dyda, F, Kosek, D.
登録日2017-10-01
公開日2018-04-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.
J. Biol. Chem., 293, 2018
6DWZ
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BU of 6dwz by Molmil
Hermes transposase deletion dimer complex with (C/G) DNA
分子名称: DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ...
著者Dyda, F, Hickman, A.B.
登録日2018-06-28
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
Nucleic Acids Res., 46, 2018
1UUT
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BU of 1uut by Molmil
The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
著者Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
登録日2004-01-10
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004
8T2J
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BU of 8t2j by Molmil
Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ...
著者Kumar, J.P, Kosek, D, Dyda, F.
登録日2023-06-06
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the catalytic domain of PPM1D/Wip1 serine/threonine phosphatase
To Be Published
1F1Z
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BU of 1f1z by Molmil
TNSA, a catalytic component of the TN7 transposition system
分子名称: CHLORIDE ION, MAGNESIUM ION, TNSA ENDONUCLEASE
著者Hickman, A.B, Li, Y, Mathew, S.V, May, E.W, Craig, N.L, Dyda, F.
登録日2000-05-21
公開日2000-06-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unexpected structural diversity in DNA recombination: the restriction endonuclease connection.
Mol.Cell, 5, 2000
1MVK
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BU of 1mvk by Molmil
X-ray structure of the tetrameric mutant of the B1 domain of streptococcal protein G
分子名称: Immunoglobulin G binding protein G, SULFATE ION
著者Frank, M.K, Dyda, F, Dobrodumov, A, Gronenborn, A.M.
登録日2002-09-25
公開日2002-10-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Core mutations switch monomeric protein GB1 into an intertwined tetramer.
Nat.Struct.Biol., 9, 2002
4ER8
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BU of 4er8 by Molmil
Structure of the REP associates tyrosine transposase bound to a REP hairpin
分子名称: DNA (32-MER), NICKEL (II) ION, TnpArep for protein
著者Messing, S.A.J, Ton-Hoang, B, Hickman, A.B, Ghirlando, R, Chandler, M, Dyda, F.
登録日2012-04-19
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease.
Nucleic Acids Res., 40, 2012
7TH0
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BU of 7th0 by Molmil
Escherichia coli RpnA-S
分子名称: Recombination-promoting nuclease RpnA
著者Zhong, A, Hickman, A.B, Storz, G, Dyda, F.
登録日2022-01-10
公開日2023-03-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Toxic antiphage defense proteins inhibited by intragenic antitoxin proteins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SJD
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BU of 8sjd by Molmil
Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon.
分子名称: DNA (46-MER), DNA (55-MER), DNA (8-MER), ...
著者Lannes, L, Dyda, F.
登録日2023-04-17
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
8EDG
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BU of 8edg by Molmil
Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon
分子名称: DNA (46-MER), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), DNA (55-MER), ...
著者Lannes, L, Dyda, F.
登録日2022-09-04
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (4.64 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
8EB5
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BU of 8eb5 by Molmil
Tandem of Hermes transposase BED domain in complex with the quasi palindrome of its transposon left-end
分子名称: Hermes transposase BED domain, Hermes transposon left-end subterminal repeats 1 and 2, ZINC ION
著者Lannes, L, Dyda, F.
登録日2022-08-30
公開日2023-08-02
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
6X68
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BU of 6x68 by Molmil
Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP)
分子名称: CALCIUM ION, Transposase, ZINC ION, ...
著者Chen, Q, Hickman, A.B, Dyda, F.
登録日2020-05-27
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
6XG8
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BU of 6xg8 by Molmil
ISCth4 transposase, pre-cleaved complex, PCC
分子名称: DNA (26-MER), Mutator family transposase
著者Kosek, D, Dyda, F.
登録日2020-06-17
公開日2020-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
6XGW
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BU of 6xgw by Molmil
ISCth4 transposase, pre-reaction complex, PRC
分子名称: DNA (32-MER), Mutator family transposase
著者Kosek, D, Dyda, F.
登録日2020-06-18
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
6X67
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BU of 6x67 by Molmil
Cryo-EM structure of piggyBac transposase strand transfer complex (STC)
分子名称: CALCIUM ION, DNA (37-MER), DNA (47-MER), ...
著者Chen, Q, Hickman, A.B, Dyda, F.
登録日2020-05-27
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
6XGX
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BU of 6xgx by Molmil
ISCth4 transposase, strand transfer complex 1, STC1
分子名称: DNA (21-MER), DNA (25-MER), DNA (47-MER), ...
著者Kosek, D, Dyda, F.
登録日2020-06-18
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
5LME
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BU of 5lme by Molmil
Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase
分子名称: ZINC ION, piggyBac transposase
著者Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E.
登録日2016-07-30
公開日2017-12-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018

 

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